Diovan HCT / Valsartan/HCTZ (Valsartan/HCTZ)

Name: Diovan HCT
Brand: Brand
SKU: 2404
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Diovan HCT

Manufacturer: Brand

Country: Turkey

Dosage: 80 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Novartis

Country: Canada

Dosage: 80 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Brand

Country: Turkey

Dosage: 160 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Novartis

Country: Canada

Dosage: 160 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Novartis

Country: Canada

Dosage: 160 mg/25 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Novartis

Country: Canada

Dosage: 320 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Novartis

Country: Canada

Dosage: 320 mg/25 mg

Qty-Price (USD):

Type:

Product: Diovan HCT

Manufacturer: Novartis

Country: Australia

Dosage: 320 mg/25 mg

Qty-Price (USD):

Generic Equivalent of Diovan HCT / Valsartan/HCTZ

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Valsartan/HCTZ

Manufacturer: Generic

Country: Canada

Dosage: 80 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Valsartan/HCTZ

Manufacturer: Generic

Country: Canada

Dosage: 160 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Valsartan/HCTZ

Manufacturer: Generic

Country: Canada

Dosage: 160 mg/25 mg

Qty-Price (USD):

Type:

Product: Valsartan/HCTZ

Manufacturer: Generic

Country: Canada

Dosage: 320 mg/12.5 mg

Qty-Price (USD):

Type:

Product: Valsartan/HCTZ

Manufacturer: Generic

Country: Canada

Dosage: 320 mg/25 mg

Qty-Price (USD):

Diovan HCT / Valsartan/HCTZ Information

Diovan HCT and Valsartan/HCTZ at CanadaPharmacyOnline.com

The manufacturer of brand-name Diovan HCT (valsartan/hydrochlorothiazide) available at this pharmacy is Novartis Pharmaceuticals Canada Inc. (Dorval, Québec). A Turkey-manufactured brand version of Diovan HCT is also available at this pharmacy.

Generic valsartan/hydrochlorothiazide tablets are also available. They are produced by several reputable pharmaceutical companies that meet the rigorous standards of Health Canada and the FDA. Generic valsartan/hydrochlorothiazide is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary based on current pharmacy stock.

Important Information about Generic Valsartan/Hydrochlorothiazide:

Generic valsartan/hydrochlorothiazide tablets contain the same active ingredients as brand-name Diovan HCT. They must meet the same effectiveness and quality standards set by Health Canada. Studies have shown that generic valsartan/hydrochlorothiazide is bioequivalent to brand-name Diovan HCT, meaning it has similar absorption and achieves plasma concentrations comparable to those of the brand-name product. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Diovan HCT (valsartan/hydrochlorothiazide) is available in the following oral strengths:
• Tablets: 80 mg/12.5 mg, 160 mg/12.5 mg, 160 mg/25 mg, 320 mg/12.5 mg, and 320 mg/25 mg film-coated tablets.

Because everyone's cardiovascular system responds differently, your exact dose must be individualized. The absolute maximum recommended daily dose for this medication is valsartan 320 mg combined with hydrochlorothiazide 25 mg once per day. Take your tablet exactly once a day, and always try to take it at the same time each day to maintain steady levels of the medication in your bloodstream. Diovan HCT can be taken with or without food, as food does not significantly affect its absorption.

Usage:

Diovan HCT is a combination prescription tablet used to treat mild-to-moderate high blood pressure. It pairs valsartan, an angiotensin II receptor blocker (ARB), with hydrochlorothiazide, a thiazide diuretic ("water pill"). This medicine is prescribed for patients who require two different medications to control their blood pressure. Diovan HCT is not intended to be your first blood pressure treatment. Your doctor must first establish you on the correct, individualized doses of valsartan and hydrochlorothiazide separately before transitioning you to this single, combined pill for your convenience. Valsartan delivers steady, consistent blood pressure control across a full 24-hour window with just a single daily dose. Additionally, it has no known acute "rebound effect," meaning that if you miss a dose, your blood pressure will not suddenly and immediately spike to a dangerous level within hours. However, valsartan has a specific therapeutic window, and skipping doses intentionally will steadily destabilize overall blood pressure management.

Mechanism of Action
Diovan HCT combines two different blood pressure-lowering medications that work together through a highly effective, complementary process. By attacking high blood pressure from two separate angles, these drugs achieve a combined result that is more powerful than either medication could achieve on its own. Valsartan belongs to a class of drugs called Angiotensin II Receptor Blockers (ARBs). It acts as a shield to block a specific hormonal pathway that normally raises your blood pressure. Hydrochlorothiazide (HCTZ) is a thiazide diuretic, commonly known as a "water pill." It targets kidney function to relieve fluid pressure in your cardiovascular system. With consistent, long-term use, hydrochlorothiazide also directly relaxes and widens your smaller peripheral blood vessels, providing a secondary, sustained layer of blood pressure control for as long as the medication is taken daily.

Take Diovan HCT exactly as your doctor prescribes, following the instructions in the product monograph. Diovan HCT may be taken with or without food, once daily.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Diovan HCT, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Diovan HCT (valsartan/hydrochlorothiazide). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Diovan HCT; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Diarrhea
• Dizziness or light-headedness
• Fatigue or tiredness
• Headache
• Increased sensitivity to sunlight
• Increased urination
• Muscle cramps
• Nausea
• Skin reactions, including rash or itching

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• High Potassium Levels (Hyperkalemia) / Low Potassium Levels (Hypokalemia): Because valsartan can cause your body to retain potassium while hydrochlorothiazide causes you to flush it out, your doctor will require routine blood draws to monitor your electrolyte balance. Muscle cramps, muscle weakness, constipation, an abnormal heart rhythm, or excessive thirst can all be signs of a shift. Severe drops in potassium or increases in calcium can cause dangerous heart rhythms, especially if you also take a heart medication called digoxin.
• Increased Risk of Skin Cancer: If you take hydrochlorothiazide long-term (typically 3 years or more), it can increase your risk of developing non-melanoma skin cancers, like basal cell or squamous cell carcinoma.
• Kidney Failure: Sudden, noticeable decrease in urine output or significant swelling in your legs and ankles.
• Lupus Flare-ups
• Severe Allergic and Skin Reactions: Hives, a severe rash, or trouble breathing. This includes rare, widespread skin blistering reactions such as Stevens-Johnson syndrome.
• Severe Low Blood Pressure (Hypotension): Severe dizziness, feeling like you are about to pass out, or actual fainting.
• Severe Swelling (Angioedema): Sudden swelling of your face, lips, tongue, or throat, or sudden difficulty breathing or swallowing.
• Sudden Eye Problems (Acute Glaucoma or Sudden Nearsightedness): Watch for sudden blurred vision, severe eye pain, or a rapid increase in eye pressure.

This is a medical emergency that requires you to stop taking Diovan HCT immediately to prevent permanent vision loss.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Diovan HCT, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Diovan HCT/valsartan/hydrochlorothiazide if:
• Active gout
• Aliskiren (Rasilez): If you have diabetes (Type 1 or Type 2) or moderate-to-severe kidney disease, you must never combine Diovan HCT with aliskiren.
• Allergies: You are allergic to valsartan, hydrochlorothiazide, or any of the inactive ingredients in the tablet.
• Angioedema: Severe swelling of the face, lips, tongue, or throat while taking valsartan or any other ARB blood pressure medication.
• Anuria: Your kidneys are completely unable to produce or pass urine.
• Breastfeeding
• Hypercalcemia
• Low blood sodium
• Pregnancy
• Severe potassium loss
• Severe, Worsening Kidney Disease: You have advanced kidney failure where waste products are actively building up in your blood (progressive azotemia). • Sulfa Allergies (Sulfonamide Hypersensitivity): You have a known allergy to sulfa-based drugs.

Tell your doctor about all of your medical conditions, past and present, before starting Diovan HCT.
• Diabetes mellitus
• Gout or hyperuricemia
• Heart failure
• Lupus erythematosus
• Personal or family history of skin cancer, light skin, or immunosuppressive therapy
• Post-myocardial infarction or cerebrovascular disease
• Renal artery stenosis
• Renal impairment
• Volume or salt depletion

Drug Interactions:

Before taking Diovan HCT, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please refer to the patient information at https://www.novartis.com/ca-en/sites/novartis_ca/files/diovan%20hct_scrip_e.pdf

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Diovan HCT. Diovan HCT may interact with other medicines, including but not limited to:
• ACE Inhibitors (e.g., Ramipril, Enalapril, Perindopril): Combining an ACE inhibitor with Diovan HCT is generally not recommended. Double-blocking this hormonal pathway increases your risk of severe low blood pressure, dangerous potassium buildup, and sudden kidney failure without providing any extra heart benefits.
• Alcohol: Drinking alcohol can heavily amplify the blood-pressure-lowering effects of Diovan HCT. This significantly increases your risk of severe dizziness, light-headedness, and fainting, especially when standing up quickly.
• Aliskiren (Rasilez): Completely restricted (contraindicated) if you have diabetes or kidney disease.
• Bile Acid Resins (Cholestyramine and Colestipol): These cholesterol-lowering medications can trap hydrochlorothiazide in your digestive tract, preventing your body from absorbing it. Always take your Diovan HCT at least 4 hours before or as long as possible after taking these resins.
• Digoxin: The hydrochlorothiazide (HCTZ) component in Diovan HCT can lower your potassium levels and raise your calcium levels.
• Lithium: Thiazide diuretics stop your kidneys from properly clearing out lithium. This can cause lithium to rapidly build up to toxic, dangerous levels in your bloodstream.
• NSAIDs (e.g., Ibuprofen, Naproxen, Indomethacin, and COX-2 Inhibitors): Regular use of common pain relievers can reduce the effectiveness of Diovan HCT by blocking the chemicals that help your blood vessels widen.
• Other Antihypertensives (Calcium Channel Blockers, Beta-Blockers, Alpha-Blockers, Nitrates): These drugs have an additive effect, meaning they will drop your blood pressure even further. Your doctor will closely monitor your numbers to ensure they do not drop too low.
• Potassium-Lowering Drugs (e.g., Loop Diuretics, Corticosteroids, Amphotericin B, ACTH): When combined with the HCTZ component of Diovan HCT, these medications can cause your body to flush out too much potassium, driving your levels dangerously low.
• Potassium-Raising Substances: Taking potassium supplements, potassium-sparing diuretics (like spironolactone), specific antibiotics (like trimethoprim), blood thinners (like heparin), or even salt substitutes containing potassium alongside the valsartan component can raise your potassium levels to dangerously high levels.
• Warfarin and Anticoagulants: Because the diuretic component removes fluid from your blood, it can alter the concentration of your blood thinners, potentially decreasing the effectiveness of warfarin and requiring more frequent clotting time (INR) checks.

Pregnancy and Breastfeeding:

Diovan HCT is contraindicated during pregnancy. Using Angiotensin II Receptor Blockers (ARBs) like valsartan during your second and third trimesters is known to cause severe injury or death to a developing baby. Hydrochlorothiazide crosses right through the placenta into the baby's bloodstream. It has been linked to fetal jaundice and dangerously low blood platelet count in newborns. Do not breastfeed when taking Diovan HCT. Hydrochlorothiazide passes directly into human breast milk. If you are a nursing mother, you and your doctor must make a clear decision to either completely stop breastfeeding or discontinue Diovan HCT.

Use in Children:

The safety and efficacy of Diovan HCT (valsartan/hydrochlorothiazide) in children and adolescents below 18 years of age have not been established, and use in this age group is not recommended.

Frequently Asked Questions about Diovan HCT / Valsartan/HCTZ at Canada Pharmacy Online

Why is Diovan HCT more affordable in Canada than in the United States?

Prescription drug prices, including Diovan HCT, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Diovan HCT I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Diovan HCT per prescription from your doctor.

Can I buy Diovan HCT from you over the counter?

No, Diovan HCT requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Diovan HCT?

Yes, generic valsartan/hydrochlorothiazide tablets are available at this pharmacy.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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