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Home > Cholesterol Medications > Lipitor or Equivalent

Lipitor (Atorvastatin)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Lipitor
Manufacturer: Pfizer
Country: Turkey
Dosage: 10 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Viatris
Country: Canada
Dosage: 10 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor (ON BACKORDER)
Manufacturer: Pfizer
Country: United Kingdom
Dosage: 20 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Viatris
Country: Canada
Dosage: 20 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Viatris
Country: Turkey
Dosage: 20 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor (ON BACKORDER)
Manufacturer: Pfizer
Country: United Kingdom
Dosage: 40 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Viatris
Country: Canada
Dosage: 40 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Viatris
Country: Turkey
Dosage: 40 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Pfizer
Country: Turkey
Dosage: 80 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor (ON BACKORDER)
Manufacturer: Pfizer
Country: United Kingdom
Dosage: 80 mg
Qty-Price (USD):
Type: drug type
Product: Lipitor
Manufacturer: Viatris
Country: Canada
Dosage: 80 mg
Qty-Price (USD):
Generic Equivalent of Lipitor
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Atorvastatin
Manufacturer: Generic
Country: Canada
Dosage: 10 mg
Qty-Price (USD):
Type: drug type
Product: Atorvastatin
Manufacturer: Generic
Country: Canada
Dosage: 20 mg
Qty-Price (USD):
Type: drug type
Product: Atorvastatin
Manufacturer: Generic
Country: Canada
Dosage: 40 mg
Qty-Price (USD):
Type: drug type
Product: Atorvastatin
Manufacturer: Generic
Country: Canada
Dosage: 80 mg
Qty-Price (USD):
Lipitor online Canadian Pharmacy

Lipitor Information

portrait medically reviewed by Carol Hou (BSc. Pharm) on June 25, 2025.
A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Lipitor and Atorvastatin at CanadaPharmacyOnline.com

The brand Lipitor was initially developed and manufactured by Pfizer and is distributed in several countries globally, including Turkey and the United Kingdom. While Pfizer may still market it in some regions, Viatris currently holds the rights to market the brand-name Lipitor in Canada following the expiration of Pfizer's original patents.

Generic atorvastatin is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Atorvastatin:

Generic atorvastatin contains the same active ingredient as brand-name Lipitor and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Lipitor. Studies have demonstrated bioequivalence between generic and brand-name atorvastatin, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic atorvastatin.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage: Brand Lipitor and generic atorvastatin are commonly available in oral tablets of 10 mg, 20 mg, 40 mg, and 80 mg.

Your doctor will determine the appropriate dose based on your needs and medical conditions.

Usage:

Lipitor (atorvastatin) is a prescription medication used alongside dietary modifications to manage various lipid disorders and reduce cardiovascular risk.

Primary Hyperlipidemia (Heterozygous Familial and Nonfamilial): Lipitor is indicated as an adjunct to diet to reduce elevated levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo-B), and triglycerides (TG). Atorvastatin effectively lowers LDL-C, Apo-B, and TC in primary hyperlipidemia. Its triglyceride-lowering effect is less pronounced and can vary in magnitude depending on the individual and the dose. HDL-C increases are typically modest.

Heterozygous Familial Hypercholesterolemia (HeFH) in patients 6 years and older: Lipitor is used alongside dietary changes to lower LDL-C, total cholesterol, and Apo-B in pediatric and adult patients with HeFH.

Homozygous Familial Hypercholesterolemia (HoFH) in adults and children 6 years and older: In individuals with the more severe genetic condition of HoFH, Lipitor is used as an adjunct to other lipid-lowering treatments further to reduce LDL-C, total cholesterol, and Apo-B. Its effectiveness as a standalone therapy is limited in this population.

Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia) in adults: When combined with dietary management, Lipitor helps to lower elevated levels of total cholesterol and triglycerides in adults with this specific lipid disorder.

Hypertriglyceridemia (Type IV Hyperlipoproteinemia) in adults: Lipitor (atorvastatin), like other statins, is crucial for lowering elevated LDL ('bad') cholesterol and significantly reducing cardiovascular risk. While lifestyle modifications are the first line for high triglycerides, and fibrates are often preferred for very high levels (especially when LDL-C isn't the primary concern), Lipitor can also effectively lower moderately elevated triglycerides, particularly when high LDL-C is present. Ultimately, the optimal medication choice is determined by the individual's complete lipid profile and overall cardiovascular risk.

Cardiovascular Risk Reduction: Lipitor is also prescribed to reduce the risk of major cardiovascular events, including myocardial infarction (heart attack), stroke, angina procedures, and cardiovascular death. This includes: • Adults without established coronary heart disease but with multiple risk factors for developing it (such as high blood pressure, low HDL-C, smoking, or a family history of early heart disease). • Adults with type 2 diabetes who have other coronary heart disease risk factors but no clinically evident heart disease.

The effectiveness of Lipitor in managing lipid disorders and reducing cardiovascular risk is significantly enhanced when integrated with comprehensive lifestyle adjustments. These include:
• A heart-healthy diet: Emphasizing fruits, vegetables, whole grains, lean proteins, and limiting saturated and trans fats, cholesterol, and sodium.
• Weight management: Achieving and maintaining a healthy body weight.
• Regular physical activity: As healthcare professionals recommend, engage in consistent aerobic exercise.

By combining medication like Lipitor with these lifestyle modifications, individuals can better control their lipid levels and significantly reduce their risk of cardiovascular disease.

Mechanism of Action:
Lipitor (atorvastatin) works primarily by inhibiting the enzyme HMG-CoA reductase in the liver, a crucial step in cholesterol synthesis. By blocking this enzyme, Lipitor disrupts the liver's ability to produce cholesterol. This decrease in intracellular liver cholesterol triggers a compensatory increase in the number of LDL receptors on the surface of liver cells. These receptors bind to and remove LDL cholesterol from the bloodstream, lowering circulating levels of this "bad cholesterol." Consequently, Lipitor's dual action of reducing cholesterol synthesis and enhancing LDL removal effectively lowers LDL cholesterol levels, playing a vital role in preventing and managing cardiovascular diseases.

Take Lipitor exactly as your doctor prescribes, following the instructions in the product monograph in Canada accompanying the medication. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Lipitor, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with Lipitor(atorvastatin). It is not an exhaustive list, and individual reactions can vary.

Common side effects - These are some common side effects of Lipitor, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Diarrhea
• Headache
• Infections, Such as the common cold or urinary tract infection (UTI)
• Joint pain (arthralgia)
• Nasal passage inflammation: Swelling and inflammation in the nasal passages and the back of the throat (nasopharyngitis)
• Nausea
• Nosebleeds (epistaxis)
• Pain in the arms or legs
• Sore throat (pharyngolaryngeal pain)
• Upset stomach (dyspepsia)

Less Common Side Effects: These side effects are not as frequent but can still occur:
• Back pain
• Belching or excessive gas (flatulence)
• Blurred vision
• Constipation
• Depression
• Dizziness
• General feeling of discomfort or illness (malaise)
• Heartburn, indigestion, or stomach discomfort
• Increased blood sugar (hyperglycemia) and an increased risk of developing diabetes have been reported as potential side effects, particularly in individuals with existing risk factors. The absolute increase in risk is relatively small and should be considered in the context of cardiovascular benefits. Symptoms of increased blood sugar may include increased thirst and urination, unusual weakness, and blurry vision.
• Increased creatine phosphokinase (CPK) levels in the blood (an enzyme that can indicate muscle damage)
• Lack or loss of strength (asthenia)
• Muscle spasms or pain (myalgia)
• Ringing in the ears (tinnitus)
• Shivering
• Sweating
• Trouble sleeping (insomnia)
• Vomiting

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions - Symptoms can range from mild (rash, itching, hives) to severe (swelling of the face, lips, tongue, or throat, difficulty breathing).
• Immune-mediated necrotizing myopathy (IMNM) is a rare condition in which the immune system attacks muscle cells, causing muscle weakness close to the body's center, difficulty lifting arms, and tiredness.
• Memory loss or confusion - These are rare and may reverse when the medication is stopped.
• Liver problems - Symptoms can include yellowing of the skin or eyes (jaundice), dark urine, pale stools, upper abdominal pain, loss of appetite, and unusual fatigue or weakness.
• Lung disease - Symptoms may include cough, shortness of breath, and weight loss.
• Myasthenia gravis—Rare reports exist of pre-existing myasthenia gravis worsening or new-onset myasthenia gravis with statin use, including Lipitor (atorvastatin). However, a definitive causal link has not been established. Patients with myasthenia gravis should discuss the potential risks and benefits with their neurologist and cardiologist, and diligent monitoring for any symptom changes is essential.
• Rhabdomyolysis - Severe muscle breakdown that can lead to kidney failure. Symptoms include severe muscle pain and weakness, and dark (reddish-brown or tea-colored) urine.
• Unexplained muscle pain, tenderness, or weakness - This could be a sign of myopathy or rhabdomyolysis, a serious condition involving muscle breakdown that can lead to kidney damage and even death. Symptoms may include dark-colored urine, fever, and unusual tiredness.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Lipitor, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Lipitor should not be used if:
• You are allergic to atorvastatin or any of the inactive ingredients in the medication; • You have active liver disease, including conditions like acute liver failure or decompensated cirrhosis. Lipitor can worsen liver function.

Tell your doctor about your medical conditions, past and present, before starting Lipitor. This is crucial because certain conditions can affect whether Lipitor is right for you. These conditions may include, but are not limited to:
• A history of muscle problems during treatment with other statins.
• A history of hemorrhagic stroke, particularly a recent one. While generally not initiated in the acute phase, the decision to start or continue statin therapy after a hemorrhagic stroke requires careful evaluation of individual risk factors, the cause of the stroke, and potential benefits by your doctor, especially considering prior statin use and the presence of atherosclerotic disease.
• Diabetes - Lipitor may increase blood sugar levels, potentially worsening diabetes control.
• Heavy alcohol use - This can increase the risk of liver damage.
• Kidney problems - You may have a higher risk of muscle problems (myopathy, rhabdomyolysis).
• Myasthenia gravis—While a definitive causal link is not established, Lipitor has been associated with worsening of pre-existing myasthenia gravis and the new onset of the condition in rare cases. Patients with myasthenia gravis should carefully discuss the potential risks and benefits with their neurologist and cardiologist. Monitoring for any changes in myasthenia gravis symptoms after starting a statin is essential.
• Untreated hypothyroidism (underactive thyroid) - This can increase the risk of myopathy.

Drug Interactions:

Before taking Lipitor, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Lipitor prescribing information.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also important to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Lipitor. Lipitor may interact with other medicines, but is not limited to:
• Certain antibiotics (clarithromycin, erythromycin): These are CYP3A4 inhibitors. CYP3A4 metabolizes Atorvastatin, so these antibiotics can increase atorvastatin levels, raising the risk of muscle problems (myopathy, rhabdomyolysis).
• Certain antifungal medications (itraconazole, ketoconazole, posaconazole, voriconazole, and to a lesser extent, fluconazole): These are CYP3A4 inhibitors and can increase atorvastatin levels, increasing the risk of side effects. Fluconazole has a weaker inhibitory effect on CYP3A4 compared to the others.
• Certain antiviral medications (especially for HIV and Hepatitis C) - lopinavir/ritonavir, elbasvir/grazoprevir, ledipasvir/sofosbuvir, many other protease inhibitors and direct-acting antivirals.
• Certain calcium channel blockers such as amlodipine, diltiazem, and verapamil.
• Digoxin (Lanoxin)—Lipitor can increase digoxin levels in the blood, potentially increasing the risk of digoxin side effects.
• Drugs that can increase the risk of Lipitor's side effects (fibrates, niacin, red yeast rice): Fibrates (like gemfibrozil and fenofibrate) can independently cause muscle problems, and their combination with statins increases this risk significantly. High doses of niacin and red yeast rice (which contains natural statins) can have additive effects, increasing the risk of myopathy and rhabdomyolysis.
• Drugs that can decrease Lipitor's effectiveness (rifampin, certain seizure medications like carbamazepine, oxcarbazepine, St. John’s Wort): These are CYP3A4 inducers, meaning they increase the activity of the enzyme that metabolizes atorvastatin, leading to lower atorvastatin blood levels and potentially reduced effectiveness.
• Immunosuppressants such as cyclosporine (should be avoided).
• Oral contraceptives - Atorvastatin may slightly elevate levels of some oral contraceptives. While this interaction is generally considered clinically minor and routine monitoring for increased side effects isn't typically recommended, patients should always discuss all their medications, including oral contraceptives, with their doctor or pharmacist.
• Other medications such as colchicine, nefazodone, leflunomide, and certain cancer drugs called kinase inhibitors.
• Warfarin - Lipitor may slightly increase the anticoagulant effects of warfarin, potentially increasing the risk of bleeding.

Alcohol:
Heavy alcohol consumption may increase the risk of liver problems, and since Lipitor can also affect the liver, it's generally advisable to limit alcohol intake while on this medication.

Grapefruit:
Consuming grapefruit or grapefruit juice can significantly increase the levels of Lipitor in your blood by inhibiting its metabolism, potentially increasing the risk of side effects, particularly muscle problems. Limiting or avoiding grapefruit and juice consumption while taking Lipitor and discussing this with your doctor or pharmacist is generally recommended.

Pregnancy and Breastfeeding

Statins, including atorvastatin, are contraindicated in pregnancy. The potential risks to the developing fetus outweigh any potential benefits for the mother in most cases of hyperlipidemia during pregnancy. Women of childbearing potential should use effective contraception while taking atorvastatin. Breastfeeding is also generally not recommended due to the potential risk to the infant.

Frequently Asked Questions about Lipitor at Canada Pharmacy Online:

Why is Lipitor more affordable in Canada than in the United States?

Prescription drug prices, including Lipitor, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

What is the difference between Lipitor 20 mg and 40 mg?

The difference in dosage represents the different amount of the same active ingredient (atorvastatin) present in each tablet.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Lipitor at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Lipitor requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for Lipitor?

Yes, there is a generic alternative for this product called atorvastatin.

What if I miss a dose of Lipitor?

If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. In that case, skip the missed dose and take your next dose at the regular time. Do not double your dose to make up for a missed one.

When is the best time to take Lipitor?

You can take Lipitor at any time of the day. However, to help you remember, try to take it at the same time each day. Some doctors recommend taking it in the evening, as cholesterol production is often higher overnight.

Can I stop taking Lipitor if my cholesterol levels go down?

Do not stop taking Lipitor without talking to your doctor. Lowering your cholesterol is a long-term process, and stopping the medication may cause your cholesterol levels to rise again, increasing your risk of heart problems and stroke.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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