Vibramycin (Doxycycline Hyclate)

Name: Vibramycin
Brand: Generic
SKU: 0409
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no brand product of Vibramycin.

Generic Equivalent of Vibramycin

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Doxycycline Hyclate Capsule

Manufacturer: Generic

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Doxycycline Hyclate Tablet

Manufacturer: Generic

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Vibramycin Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on July 18, 2025.

Doxycycline at CanadaPharmacyOnline.com

The brand name Vibramycin is currently not available (at this pharmacy).

Generic Doxycycline is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Doxycycline:

Generic doxycycline contains the same active ingredient as brand-name Vibramycin and is required to meet the same safety, effectiveness, and quality standards as the brand-name product. This means it is designed to work in the same way as Vibramycin. Studies have demonstrated bioequivalence between generic and brand-name doxycycline, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic doxycycline.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage

Vibramycin is commonly available in 100 mg oral capsules and tablets at this pharmacy.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage

Vibramycin (doxycycline) is a broad-spectrum antibiotic used to treat a wide variety of bacterial infections. It belongs to the tetracycline class of antibiotics. Common uses include:
• Bacterial infections: Respiratory tract infections (e.g., pneumonia, bronchitis), urinary tract infections, skin infections (e.g., acne, rosacea, cellulitis), intestinal infections, eye infections, and sexually transmitted infections (e.g., chlamydia, syphilis).
• Other infections: Lyme disease, cholera, typhus, Rocky Mountain spotted fever, anthrax, leptospirosis, malaria.
• Prophylaxis: To prevent malaria, Scrub typhus, or traveller’s Diarrhea when travelling to specific regions or to prevent serious illness post-exposure to anthrax.

Mechanism of Action
Vibramycin (doxycycline) is a bacteriostatic antibiotic, meaning it inhibits the growth and reproduction of bacteria rather than directly killing them. It works by binding to the 30S ribosomal subunit of susceptible bacteria. This binding interferes with the binding of transfer RNA (tRNA) to messenger RNA (mRNA) at the ribosomal subunit, thereby preventing the addition of new amino acids to polypeptide chains. This inhibition of bacterial protein synthesis stops bacterial growth, allowing the body's immune system to clear the infection.

Take Vibramycin exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Vibramycin, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Vibramycin, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects - The following are some common side effects of Vibramycin; other side effects may occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abdominal pain
• Changes in skin colour (hyperpigmentation)
• Diarrhea
• Difficulty swallowing
• Dyspepsia (indigestion)
• Esophageal irritation or ulceration (painful swallowing, heartburn)
• Headache
• Increased sensitivity to sunlight (photosensitivity), leading to severe sunburn
• Lightheadedness
• Nausea
• Skin rash
• Vomiting

Serious Side Effects - These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions: Rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising.
• Clostridioides difficile-associated diarrhea (CDAD): Severe or prolonged diarrhea, abdominal cramps, fever, or blood/mucus in stool.
• Esophagitis or esophageal ulceration: Severe chest pain, difficulty, or pain when swallowing.
• Hepatotoxicity (liver damage): Symptoms include yellowing of the skin or eyes (jaundice), dark urine, and persistent nausea/vomiting.
• Intracranial hypertension (pseudotumor cerebri): Increased pressure inside the skull. Symptoms include severe headache, blurred vision, double vision, temporary or permanent vision loss, dizziness, or nausea. More common in overweight women of childbearing age.
• Severe skin reactions: Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS syndrome), with symptoms like rash, fever, blistering, peeling skin.
• Superinfection: Development of new infections, including fungal infections (e.g., oral or vaginal thrush) or resistant bacterial infections.
• Tooth discoloration: Permanent discoloration of teeth (yellow-gray-brown) in children, especially those under 8 years of age.

Long-Term Side Effects - Long-term or repeated use of Vibramycin may lead to:
• Increased risk of Clostridioides difficile-associated diarrhea (CDAD).
• Intracranial hypertension (can occur in short-term or with long-term use)
• Liver damage (rare).
• Permanent tooth discoloration in children under 8 years of age.
• Photosensitivity.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Vibramycin, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Vibramycin should not be used if you:
• Are allergic to doxycycline or any other tetracycline antibiotic (e.g., minocycline, tetracycline) or any of Vibramycin's ingredients.
• Are breastfeeding, as doxycycline passes into breast milk.
• Are pregnant or trying to become pregnant
• Are in the second or third trimester of pregnancy (when the risk of permanent tooth discoloration and inhibition of bone growth in the fetus is highest)
• Are taking isotretinoin (Accutane) due to an increased risk of intracranial hypertension.

Tell your doctor about all of your medical conditions, past and present, before starting Vibramycin. This is crucial because certain conditions affect whether Vibramycin is right for you. These conditions may include, but are not limited to:
• History of esophageal irritation or ulceration: Doxycycline should be taken with plenty of water and while upright to prevent this.
• History of yeast infections or fungal infections: Doxycycline may increase the incidence of vaginal candidiasis or other fungal overgrowth.
• Impaired liver function.
• Intracranial hypertension (pseudotumor cerebri) is prevalent in overweight women.
• Myasthenia gravis: Doxycycline may worsen symptoms.
• Porphyria.
• Systemic lupus erythematosus (SLE): Doxycycline may exacerbate SLE.

Drug Interactions

Before taking Vibramycin, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the product labeling information | Pfizer website at https://labeling.pfizer.com/ShowLabeling.aspx?id=15256.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Vibramycin. Vibramycin may interact with other medicines, but is not limited to:
• Antacids (containing aluminum, calcium, magnesium): Take doxycycline 2 hours before or 6 hours after.
• Anticoagulants (blood thinners, e.g., warfarin): Doxycycline may potentiate the effect of anticoagulants, increasing the risk of bleeding. Close monitoring of INR is advised.
• Barbiturates (e.g., phenobarbital): Can decrease doxycycline effectiveness.
• Bismuth subsalicylate (e.g., Pepto Bismol): Take doxycycline 2 hours before or 6 hours after.
• Carbamazepine: Can decrease doxycycline effectiveness.
• Iron supplements: Take doxycycline 2 hours before or 6 hours after.
• Isotretinoin (Accutane): Concurrent use is contraindicated due to the increased risk of intracranial hypertension.
• Methotrexate: Doxycycline may increase methotrexate levels, leading to increased toxicity.
• Oral Contraceptives (birth control pills): The effect of doxycycline on the efficacy of oral contraceptives has been shown in current evidence to have no consistent or significant reduction in contraceptive efficacy. Some healthcare providers may still recommend using an alternative or additional form of birth control during and for a short period after treatment. Talk to your doctor or pharmacist.
• Penicillin antibiotics: Doxycycline, being bacteriostatic, may interfere with the bactericidal action of penicillin. In most clinical situations, this interaction is not considered to be clinically significant. Consult your doctor or pharmacist to discuss your specific situation.
• Phenytoin (Dilantin): Can decrease doxycycline effectiveness.
• Retinoids (oral): Increased risk of intracranial hypertension.

Alcohol
It is generally best to avoid or limit alcohol consumption while taking Vibramycin. Heavy or chronic alcohol use may decrease the effectiveness of doxycycline. Additionally, both alcohol and doxycycline can be metabolized by the liver, and combining them could potentially increase liver strain or side effects like nausea and vomiting.

Pregnancy and Breastfeeding

Vibramycin is contraindicated during pregnancy, particularly in the second and third trimesters, due to the risk of permanent tooth discoloration (yellow-gray-brown) and inhibition of bone growth in the fetus. If you become pregnant while taking Vibramycin, contact your doctor immediately. Doxycycline passes into breast milk. Therefore, breastfeeding is not recommended during treatment with Vibramycin due to the potential for serious adverse effects on the nursing infant, including tooth discoloration and inhibition of bone growth.

Use in Children

Vibramycin is generally contraindicated in children under 8 years of age due to the risk of permanent tooth discoloration and enamel hypoplasia. However, in cases of severe or life-threatening infections (e.g., anthrax, Rocky Mountain spotted fever), the benefits of doxycycline may outweigh this risk, and it may be used in younger children under strict medical supervision.

Use in the Elderly

Elderly patients on Vibramycin must be closely monitored by their healthcare provider. Older adults may be more susceptible to specific side effects, particularly gastrointestinal issues like esophageal irritation. They may also have an increased risk of superinfections due to their overall health status.

Frequently Asked Questions about Vibramycin at Canada Pharmacy Online:

Why is Vibramycin more affordable in Canada than in the United States?

Prescription drug prices, including Vibramycin, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Vibramycin at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Vibramycin requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to take doxycycline?

Doxycycline should be taken with a full glass of water to reduce the risk of esophageal irritation. It's generally recommended to remain upright for at least 30 minutes (or even an hour) after taking the medication. While it can be taken with or without food, taking it with food or milk may help reduce stomach upset. Avoid taking it immediately before lying down, especially at bedtime. Your doctor will advise on the best dosing schedule for your specific infection or condition.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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