Nevanac (Nepafenac)

Name: Nevanac
Brand: Novartis
SKU: 6597
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Nevanac Opht. Suspension

Manufacturer: Novartis

Country: Canada

Dosage: 0.1 %/5 ml

Qty-Price (USD):

Type:

Product: Nevanac Opht. Suspension

Manufacturer: Alcon

Country: India

Dosage: 0.1 %/5 ml

Qty-Price (USD):

Generic Equivalent of Nevanac

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Nepafenac Opht. Suspension (Nepalact Z - Sun Pharma)

Manufacturer: Generic

Country: India

Dosage: 0.1 %/5 ml

Qty-Price (USD):

Nevanac Information

medically reviewed by Carol Hou (BSc. Pharm) on August 25, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Nevanac and Nepafenac at CanadaPharmacyOnline.com

The brand name Nevanac, manufactured by Novartis in Canada, is also manufactured by Alcon in India.

Generic Nepafenac is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturers of your dispensed medication may vary.

Important Information about Generic Nepafenac

Generic nepafenac contains the same active ingredient as brand-name Nevanac and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Nevanac. Studies have shown that generic nepafenac is bioequivalent to the brand-name Nevanac, meaning it has similar absorption rates and reaches identical concentrations in the bloodstream. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts.

Dosage:

The brand Nevanac and the generic nepafenac are ophthalmic suspensions (eye drops) commonly available in a strength of 0.1%, typically in a 5 mL bottle (at this pharmacy).

Like all pharmaceutical products, it contains not only the active ingredient (nepafenac) but also various inactive ingredients necessary for its formulation.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Nevanac (nepafenac) is a nonsteroidal anti-inflammatory drug (NSAID) in an ophthalmic suspension used to manage eye pain and inflammation after cataract surgery. It's also prescribed for diabetic patients to lower their risk of developing macular edema, a type of swelling in the back of the eye, following the procedure.

Mechanism of Action:
Nevanac works by first being absorbed into the eye as an inactive form called nepafenac. Once inside the eye, it quickly changes into its active form, amfenac. This active form then blocks certain enzymes (called COX enzymes) that are responsible for creating substances called prostaglandins. Prostaglandins are key chemicals that cause pain, swelling, and inflammation in the eye. By stopping the production of these prostaglandins, Nevanac effectively reduces the pain and inflammation often experienced after cataract surgery, and also helps prevent related complications, such as macular edema.

Take Nevanac exactly as prescribed by your doctor, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Nevanac, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Nevanac (nepafenac). It is not an exhaustive list, and individual reactions can vary.

Common side effects – The following are some common side effects of Nevanac; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Blurred vision
• Capsular opacity
• Decreased vision
• Foreign body sensation in the eyes
• Headache
• Increased intraocular pressure
• Nausea
• Sticky sensation

Other Potential Side Effects (less common):
• Conjunctival edema
• Corneal edema
• Corneal epithelial defect
• Crusty eyelids
• Dry eye
• Dizziness
• Eye discomfort
• Eye pain
• Itching of the eye
• Lid margin crusting
• Ocular hyperemia (redness)
• Ocular pruritus (itchy eye)
• Photophobia (sensitivity to light)
• Tearing
• Vomiting

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions (e.g., swelling of the face, lips, tongue, throat, severe rash, hives, difficulty breathing)
• Bleeding in the front of the eye (hyphema)
• Changes in vision (significant blurriness, sudden vision loss, tunnel vision, seeing halos around lights)
• Corneal complications (e.g., corneal erosion, thinning, ulceration, perforation, impaired healing, corneal scar, corneal opacity)
• Eye discharge or crusting
• Eye pain (severe or worsening)
• Eye swelling
• Fever
• Increased blood pressure
• Inflammation of the iris (iritis)
• Inflammation of the surface of the eye (keratitis)
• Swollen eyelids

Contraindications:

The following is not an exhaustive list of contraindications. Before taking Nevanac, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do NOT use Nevanac if you are allergic to:
• A known allergy to the eye drops or any of its components.
• An allergic reaction to other NSAIDs, such as a severe asthma attack, hives, or a rash after taking aspirin, ibuprofen (Advil), or naproxen (Aleve).

Tell your doctor about all of your medical conditions, past and present, before starting Nevanac. This is crucial because conditions can affect whether Nevanac is right for you. These conditions may include, but are not limited to:
• A history of bleeding problems or are receiving other medications that may prolong bleeding time (e.g., blood thinners like warfarin, antiplatelet medications), as Nevanac may increase ocular bleeding.
• A history of complicated ocular surgeries, corneal denervation, corneal epithelial defects, diabetes mellitus, ocular surface diseases (e.g., dry eye syndrome), rheumatoid arthritis, or have had repeated ocular surgeries within a short period, as these may increase the risk of corneal adverse events (e.g., keratitis, corneal thinning, ulceration, perforation).
• An acute ocular infection, as Nevanac may mask the signs of disease.
• Wearing contact lenses, as Nevanac contains benzalkonium chloride, which can be absorbed by soft contact lenses and cause eye irritation. Contact lenses should be removed before application and reinserted at least 15 minutes later.
• Using other topical eye medications, especially corticosteroids, as concomitant use of topical NSAIDs and topical steroids may increase the potential for healing problems.

Drug Interactions:

Before taking Nevanac, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the official Nevanac product monograph | Novartis.com: https://www.novartis.com/ca-en/sites/novartis_ca/files/nevanac_scrip_e.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, or significant dietary changes, as these could interact with Nevanac. Nevanac may interact with other medicines, but is not limited to:
• Anticoagulants and Antiplatelet Medications: Nevanac, as an NSAID, can interfere with blood clotting. Using it concurrently with "blood thinners" (e.g., warfarin) or antiplatelet medications (e.g., clopidogrel, aspirin) may increase the risk of bleeding in or around the eye (including hyphema) or other areas of the body. Your doctor will need to monitor you closely if you use these medications together.
• Other NSAIDs: There's a potential for cross-sensitivity between nepafenac and other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, aspirin, or diclofenac. Using multiple NSAIDs, even topically, may increase the risk of side effects.
• Prostaglandin Analogues: While there's limited data, concomitant use of Nevanac with prostaglandin analogues (another class of eye drops often used for glaucoma, such as bimatoprost or latanoprost) is generally not recommended due to potential interactions related to their mechanisms of action.
• Topical Corticosteroids (Steroid Eye Drops): Concomitant use of topical NSAIDs like Nevanac and topical corticosteroids (e.g., prednisolone ophthalmic, dexamethasone ophthalmic) may increase the potential for healing problems in the eye, particularly the cornea.

Pregnancy and Breastfeeding:

Nevanac use during pregnancy and breastfeeding requires careful consideration. While systemic absorption from eye drops is low, it's generally not recommended in pregnancy, especially late in term, due to potential risks to the developing baby's heart.

There is no conclusive data on whether Nevanac (nepafenac) is excreted in human milk. Although studies in lactating rats have shown its presence in their milk, the clinical significance for humans is unknown. Therefore, a discussion with a healthcare professional is recommended to weigh the potential risks to the infant against the therapeutic benefits for the mother before breastfeeding while using this medication.

Frequently Asked Questions about Nevanac at Canada Pharmacy Online:

Why is Nevanac more affordable in Canada than in the United States?

Prescription drug prices, including Nevanac, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Can Nevanac be used on a dog?

Nevanac is a nonsteroidal anti-inflammatory (NSAID) eye drop that can reduce pain and swelling in the eye. It is typically used after cataract surgery, but it can be prescribed for pet use. Consult your veterinarian to determine if using Nevanac is suitable for your dog.

I have another eye drop medication I use. Can I use it while taking Nevanac?

Yes, but wait at least 10 minutes after administering Nevanac to use any other eye drops.

Can I take Nevanac while wearing my contact lenses?

No, you should not use Nevanac while wearing contact lenses. It may contain a preservative that could discolor the lenses. Wait at least 15 minutes after using the medicine before putting in your contacts.

My bottle of Nevanac has changed color. What should I do?

If your prescription has changed color or contains particles, return it to your pharmacy and request that it be replaced.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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