Xiidra (Lifitegrast)

Name: Xiidra
Brand: Bausch & Lomb
SKU: 7507
Availability: InStock

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Qty-Price (USD)

Type:

Product: Xiidra 60 Single dose vials

Manufacturer: Bausch & Lomb

Country: Canada

Dosage: 5 %/0.2 ml

Qty-Price (USD):

Generic Equivalent of Xiidra

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There is no generic product of Xiidra.

Xiidra Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on August 22, 2025.

Xiidra and Lifitegrast at CanadaPharmacyOnline

The brand name Xiidra, manufactured by Bausch + Lomb, is available in Canada.

Generic lifitergrast is currently unavailable (at this pharmacy).

Dosage:

Xiidra is a 5% ophthalmic solution (eye drop) provided in a carton containing a total of 60 single-use containers. Each preservative-free container holds 0.2 mL of the solution and is typically packaged in 12 foil pouches with five containers per pouch. This arrangement provides a 30-day supply, with a recommended dosage of one drop in each eye, twice daily.

Your doctor will determine the appropriate dose based on your individual needs.

Usage:

Xiidra, also known as lifitegrast, is a prescription eye drop specifically designed to treat the signs and symptoms of dry eye disease (DED). By using one drop in each eye, twice a day, you can help relieve discomfort, blurred vision, and irritation associated with dry eyes.

Mechanism of Action:
Xiidra (lifitegrast) works to relieve dry eye disease by targeting the underlying inflammation that causes it. It achieves this by acting as an antagonist of lymphocyte function-associated antigen-1 (LFA-1). Lifitegrast binds to the LFA-1 protein on the surface of T-cells, blocking its interaction with intercellular adhesion molecule-1 (ICAM-1). This action prevents the activation and migration of T-cells to the ocular surface, thereby breaking the inflammatory cycle and reducing the signs and symptoms of dry eye disease. This mechanism helps to soothe the eye and provide relief from the irritation and discomfort associated with dry eyes.

Take Xiidra exactly as prescribed by your doctor, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Xiidra, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Xiidra (lifitegrast). It is not an exhaustive list, and individual reactions can vary.

Common side effects – The following are some common side effects of Xiidra; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Blurred vision (right after application)
• Eye irritation or discomfort (right after application
• Unusual or bad taste in the mouth (dysgeusia)

Other Potential Side Effects (less common):
• Headache
• Sinusitis (sinus infection)

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any signs of an allergic reaction, such as
• Difficulty breathing
• Hives
• Swelling of the face, tongue, or throat

Contraindications:

The following is not an exhaustive list of contraindications. Before taking Xiidra, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Xiidra should not be used if:
• You have a known hypersensitivity or allergy to lifitegrast or any of the other ingredients in Xiidra.

Tell your doctor about all of your medical conditions, past and present, before starting Xiidra. This is crucial because conditions can affect whether Xiidra is right for you. These conditions may include, but are not limited to:
• Any active eye infections or inflammation: It's generally best to treat these conditions before starting Xiidra.
• A history of ocular surgery: Your doctor will need to take this into account before prescribing the medication.

Contact Lenses:
• As a reminder, please remove your contact lenses before applying Xiidra and wait at least 15 minutes before reinserting them.

Drug Interactions:

Before taking Xiidra, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the Xiidra prescribing information | Bausch and Lomb at https://pi.bausch.com/globalassets/pdf/packageinserts/pharma/xiidra-prescribing-information.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Xiidra may interact with other medicines, especially other eye drops. It's generally recommended to separate the administration of each medication by at least 15 minutes. This helps ensure that one eye drop doesn't wash out the other, allowing each drug to be absorbed effectively. Always follow your doctor's instructions regarding the use of multiple eye drops.

Pregnant and Breastfeeding:

There are no specific, human-based studies on the use of Xiidra (lifitegrast) during pregnancy or breastfeeding, so the safety of the medication in these situations is not definitively known. Because the medication is an eye drop, the amount that enters the bloodstream is considered low. Suppose you are pregnant or breastfeeding, or plan to be. In that case, you should have a thorough discussion with your doctor about whether the potential benefits of treating your dry eye disease with Xiidra outweigh any potential, though unknown, risks to the baby.

Frequently Asked Questions about Xiidra at Canada Pharmacy Online:

Why is Xiidra more affordable in Canada than in the United States?

Prescription drug prices, including Xiidra, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

How much does Xiidra cost in Canada?

At our pharmacy, the cost of Xiidra 5%/0.2 mL starts at $349.99 for 60 single-dose vials.

Can I buy Xiidra over the counter from you?

No, Xiidra requires a prescription from your doctor. We are unable to sell this product without a valid prescription from your doctor.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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