Advicor (Niacin/Lovastatin)

Name: Advicor
Brand: Generic
SKU: 6016
Availability: InStock

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There is no brand product of Advicor.

Generic Equivalent of Advicor

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Type:

Product: Niacin/Lovastatin Two Separate Pills

Manufacturer: Generic

Country: Canada

Dosage: 500 mg/20 mg

Qty-Price (USD):

Advicor Information

Niacin/Lovastatin at CanadaPharmacyOnline.com

The manufacturer of brand-name Advicor (lovastatin/niacin extended-release) is Abbott Laboratories. Brand-name Advicor extended-release combination tablets have been discontinued in Canada and are unavailable.

Generic niacin/lovastatin is available as two separate pills (generic niacin and generic lovastatin) taken together to achieve the same therapeutic outcome. The specific manufacturer of the dispensed medication may vary depending on pharmacy inventory. Generic niacin/lovastatin is sourced from manufacturers that meet applicable regulatory standards.

Important Information about Generic Niacin/lovastatin

Generic niacin/lovastatin contains the same active ingredient as brand-name Advicor. It must meet the same effectiveness and quality standards. This means it is designed to work like Advicor. Studies have shown that generic niacin/lovastatin is bioequivalent to brand-name Advicor, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

Dosage:

Generic niacin/lovastatin is available in the following oral strengths at this pharmacy:

Tablets: 500 mg niacin extended-release tablets and 20 mg lovastatin tablets (dispensed as separate pills).

Dosage is individualized and based on tolerability.

Usage:

Generic niacin and lovastatin are a combination of two lipid-lowering agents: lovastatin, an HMG-CoA reductase inhibitor (statin), and niacin extended-release (extended-release nicotinic acid), indicated as adjunctive therapy to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides, and to increase HDL cholesterol in patients with primary hyperlipidemia or mixed dyslipidemia.

Mechanism of Action
This therapy combines two different cholesterol-lowering therapies that attack plaque-building fats from two distinct angles. Lovastatin works directly inside your liver to block the specific enzyme responsible for producing cholesterol. This encourages your liver cells to clear existing "bad" cholesterol (LDL) from your bloodstream. Niacin reduces the liver's ability to produce the fatty transport vehicles (VLDL), lowering total triglycerides while slowing the clearance of "good" cholesterol (HDL), so it stays in your blood longer.

Take both pills exactly as your doctor prescribes, following the instructions in the product monograph. Typically, generic lovastatin is taken once daily with your evening meal, while generic niacin extended-release is taken at bedtime with a low-fat snack. Swallow both types of tablets whole. Do not crush, chew, or break them. To reduce niacin-related flushing, your doctor may approve taking a regular-strength aspirin 30 minutes before your bedtime niacin dose.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting generic niacin/lovastatin, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of generic lovastatin and niacin ER. It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of niacin/lovastatin; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning.
• Flushing (warmth, redness, tingling, or itching of the skin, usually of the face, neck, and chest)
• Headache
• Nausea or stomach upset.
• Pruritus (itching)

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• High Blood Sugar (Hyperglycemia) and Worsening Diabetes: Niacin can raise blood glucose levels. Monitor blood glucose closely in patients with diabetes or pre-diabetes.
• Liver Toxicity (Hepatotoxicity): Jaundice, dark urine, severe fatigue, or upper abdominal pain. Cases of severe hepatic toxicity have been reported with niacin ER, particularly at higher doses. Liver function tests are monitored before and during treatment.
• Myopathy or Rhabdomyolysis (Muscle Damage): Unexplained muscle pain, weakness, or tenderness, particularly if accompanied by dark urine (myoglobinuria).

The risk of myopathy with lovastatin is increased when combined with certain drugs (see Drug Interactions). Contact your doctor immediately if you develop unexplained muscle symptoms.
• Severe Allergic Reaction: Hives, swelling of the face, lips, tongue, or throat, or difficulty breathing.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting niacin/lovastatin, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take lovastatin/niacin ER if:
• Active liver disease or unexplained persistent elevations in liver enzymes.
• Allergies: Known hypersensitivity to lovastatin, niacin, or any ingredient in either tablet.
• Arterial Bleeding (Active).
• Pregnancy or Breastfeeding: Statins are contraindicated during pregnancy and breastfeeding.
• Strong CYP3A4 inhibitors (e.g., itraconazole, ketoconazole, HIV protease inhibitors, clarithromycin, erythromycin, nefazodone): These increase lovastatin levels and the risk of myopathy.

Tell your doctor about all of your medical conditions, past and present, before starting generic niacin/lovastatin. This is crucial as certain conditions affect the drug's safety.
• Diabetes
• Gout
• Kidney disease
• Peptic ulcer disease

Drug Interactions:

Before taking these medications, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the product monograph at https://pdf.hres.ca/dpd_pm/00011748.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with niacin/lovastatin. Generic niacin or lovastatin may interact with other medicines, including but not limited to:
• Antidiabetic agents: Niacin may raise blood glucose, reducing the efficacy of antidiabetic medications. Monitor blood glucose closely.
• Antihypertensive drugs: Niacin may potentiate the effects of ganglionic-blocking agents and vasoactive antihypertensives, leading to postural hypotension.
• Aspirin: Taking aspirin 30 minutes before generic niacin/lovastatin can reduce flushing. Discuss with your doctor before adding aspirin.
• Bile acid sequestrants (e.g., cholestyramine, colestipol): May bind niacin and reduce its absorption. Administer niacin/lovastatin at least 4 to 6 hours apart from these drugs.
• CYP3A4 inhibitors (e.g., itraconazole, clarithromycin, cyclosporine): Contraindicated or to be avoided as they raise lovastatin levels markedly, increasing myopathy risk.

Pregnancy and Breastfeeding:

These medications are contraindicated during pregnancy. Statins, including lovastatin, can harm the developing fetus. Stop niacin/lovastatin immediately if you become pregnant and contact your doctor. These medications are also contraindicated during breastfeeding, as both lovastatin and niacin may pass into breast milk.

Use in Children:

Generic niacin/lovastatin is not established for use in pediatric patients. It is not recommended for use in children.

Frequently Asked Questions about Advicor at Canada Pharmacy Online

Why is Advicor more affordable in Canada than in the United States?

Prescription drug prices, including Advicor, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Advicor I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of generic niacin/lovastatin per your doctor's prescription.

Can I buy Advicor from you over the counter?

No, generic niacin/lovastatin requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Advicor?

The generic niacin/lovastatin is available as two separate pills.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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