Amitiza (Lubiprostone)

Name: Amitiza
Brand: Takeda
SKU: 6552
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Amitiza Capsule

Manufacturer: Takeda

Country: United States

Dosage: 24 mcg

Qty-Price (USD):

Generic Equivalent of Amitiza

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Lubiprostone (Lubowel - Sun PHarma) Soft Gelatin Capsule

Manufacturer: Generic

Country: India

Dosage: 24 mcg

Qty-Price (USD):

Amitiza Information

medically reviewed by Carol Hou (BSc. Pharm) on May 20, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Amitiza and Lubiprostone at CanadaPharmacyOnline.com

Brand Amitiza (lubiprostone), manufactured by Takeda, is available in many countries worldwide, including the United States.

Generic lubiprostone is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Lubiprostone:

Generic lubiprostone contains the same active ingredient as brand-name Amitiza and is required to meet the same safety, effectiveness, and quality standards.

This means it is designed to work in the same way as Amitiza. Studies have demonstrated bioequivalence between generic and brand-name lubiprostone, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic lubiprostone, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

The brand Amitiza is available in 24 mcg oral capsules. The generic lubiprostone is available in oral soft gelatin capsules.

Your doctor will determine the appropriate dosage based on the individual needs and medical conditions.

Usage:

Amitiza (lubiprostone) is a prescription medication used to treat certain types of constipation, such as chronic idiopathic constipation (CIC) and opioid-induced constipation (OIC). CIC is long-lasting constipation with no known cause, while OIC is constipation caused by taking opioid pain medications. Amitiza may also be used to treat irritable bowel syndrome with constipation (IBS-C) in women (refer to the product labeling information).

Mechanism of Action:
Lubiprostone is a chloride channel activator. It activates chloride channels in the cells lining the intestines. This helps to bring more water into the bowel, which then helps to create softer stools and to make the bowel move those stools along.

Take Amitiza exactly as your doctor prescribes, following the instructions in the Highlights of Prescribing Information - Takeda. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Amitiza, it is essential to discuss all potential side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Amitiza, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects – These are examples of some common side effects of Amitiza, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Abdominal pain
• Bloating
• Diarrhea
• Dizziness
• Gas
• Headache
• Nausea

Serious or rare side effects – Stop taking Amitiza and seek immediate medical attention right away if you experience any of the following:
• Allergic reactions, including angioedema, hives, and trouble breathing
• Gastrointestinal upset, including severe diarrhea, severe abdominal pain, and persistent nausea
• Low blood pressure, including dizziness, fainting, and difficulty concentrating
• Shortness of breath

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Amitiza.

Amitiza should not be used if:
• Are allergic to lubiprostone or any of the inactive ingredients in Amitiza
• You have a gastrointestinal obstruction
• You have severe diarrhea

Tell your doctor about all of your medical conditions, past and present, before starting Amitiza. This is crucial because certain conditions can affect whether Amitiza is right for you. These conditions may include, but are not limited to:
• Liver disease
• Kidney disease

Dizziness and Fainting:
Amitiza may cause dizziness or fainting. Avoid getting up too fast from a sitting or lying position. Otherwise, you may feel dizzy. Avoid driving, operating machinery, or engaging in activities that require alertness until you understand how it affects you.

Dyspnea (shortness of breath):
Some patients have reported experiencing dyspnea, chest tightness, and throat constriction, generally within an hour of the first dose. This side effect should go away within 3 hours, but it may occur again when you take your next dose. Consult your doctor if this side effect becomes bothersome.

Nausea:
Amitiza may cause nausea. Taking the medicine with food may reduce the symptoms of nausea.

Drug Interactions:

Before taking Amitiza, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, consult the Drug Label Information | DailyMed, and discuss any concerns with your healthcare provider.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Amitiza can interact with other medicines but is not limited to methadone, furosemide, loperamide, and diphenhydramine.

Pregnancy and Breastfeeding:

If you are pregnant or become pregnant, tell your doctor before using Amitiza. It is unknown if lubiprostone will harm an unborn baby. It is crucial to discuss the risks and benefits of using Amitiza with your doctor before taking it. If you are breastfeeding or plan to breastfeed, inform your doctor. It is unknown if lubiprostone is excreted in human breast milk. Tell your doctor if you notice diarrhea in your nursing baby. It is crucial to discuss the risks and benefits of using Amitiza with your doctor before taking it.

Frequently Asked Questions about Amitiza at Canada Pharmacy Online

Why is Amitiza more affordable in Canada than in the United States?

Prescription drug prices, including Amitiza, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I cut or split an Amitiza capsule?

It is generally not recommended to cut, split, or chew Amitiza tablets. Crushing, chewing, opening, or breaking the capsule could potentially affect how the medication is released or absorbed.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Amitiza capsules I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Amitiza at one time, as per your doctor's prescription.

Can I buy Amitiza over the counter from you?

No, Amitiza requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

How to take Amitiza?

Take this medicine twice daily with food and water. Your dose will depend on your medical condition and what you are treating.

Blog Posts:

IBS: Not Just A Grumpy Gut
The Most Prevalent Gut Disorder Actually A Gut-Brain Disorder

Latest News:

The Efficacy of Lubiprostone in Patients of Constipation: An Updated Systematic Review and Meta‐Analysis (study published on January 15, 2025)

Similar Drugs in the category of Bowel Cleansing:

Bi-Peglyte Prep Kit

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers