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Azor (Olmesartan Medoxomil/Amlodipine Maleate)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Azor Tablet
Manufacturer: Organon
Country: Australia
Dosage: 20 mg/5 mg
Qty-Price (USD):
Type: drug type
Product: Azor Film Coated Tablet
Manufacturer: Daiichi Sankyo
Country: United Kingdom
Dosage: 20 mg/5 mg
Qty-Price (USD):
Type: drug type
Product: Azor Tablet
Manufacturer: Daiichi Sankyo
Country: Turkey
Dosage: 20 mg/5 mg
Qty-Price (USD):
Type: drug type
Product: Azor Tablet
Manufacturer: Daiichi Sankyo
Country: Turkey
Dosage: 20 mg/5 mg
Qty-Price (USD):
Type: drug type
Product: Azor Tablet
Manufacturer: Daiichi Sankyo
Country: Turkey
Dosage: 40 mg/10 mg
Qty-Price (USD):
Type: drug type
Product: Azor Tablet
Manufacturer: Daiichi Sankyo
Country: Turkey
Dosage: 40 mg/5 mg
Qty-Price (USD):

Generic Equivalent of Azor
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Olmesartan Medoxomil/Amlodipine Maleate Tablet (WinBP AM - Abbott)
Manufacturer: Generic
Country: India
Dosage: 20 mg/5 mg
Qty-Price (USD):
Type: drug type
Product: Olmesartan Medoxomil/Amlodipine Maleate Tablet (Olsar A - Unichem)
Manufacturer: Generic
Country: India
Dosage: 40 mg/5 mg
Qty-Price (USD):

Azor Information

portrait medically reviewed by Dr. HaVy Ngo, Pharmacist on April 23, 2025.

Azor and Olmesartan Medoxomil/Amlodipine Maleate at CanadaPharmacyOnline.com

The brand Azor was originally manufactured by Daiichi Sankyo. It is also marketed as another brand name, Sevikar, available in many countries, including the United Kingdom and Turkey. In Australia, Sevikar is marketed and supplied by Organon.

Generic olmesartan medoxomil/amlodipine maleate is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Olmesartan:

Generic olmesartan medoxomil/amlodipine maleate contains the same active ingredients as the brand-name Azor and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Azor. Studies have demonstrated bioequivalence between generic and brand-name Azor, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic olmesartan medoxomil/amlodipine maleate.

For more information about generic drug approval and bioequivalence, you can visit https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

The brand Azor is available in strengths of 20 mg/ 5 mg, 40 mg/ 5 mg, and 40 mg/ 10 mg oral tablets. Generic olmesartan medoxomil/amlodipine maleate is available in strengths of 20 mg/5 mg and 40 mg/5 mg oral tablets.

Your doctor will determine your safe and effective dosage based on your individual needs.

Usage:

Azor (olmesartan) is a prescription medication used to treat high blood pressure (hypertension) in adults. It may be used alone or in conjunction with other antihypertensive agents. (source: the product labeling information)

Mechanism of Action:
Azor's antihypertensive action stems from the combined mechanisms of amlodipine and olmesartan. Amlodipine, a calcium channel blocker, inhibits calcium influx into vascular smooth muscle cells, causing arterial vasodilation and reduced peripheral resistance. Olmesartan, an angiotensin II receptor blocker, blocks the binding of angiotensin II to AT1 receptors, preventing vasoconstriction and aldosterone release, leading to vasodilation and reduced fluid retention. This dual action, targeting both calcium-dependent vasoconstriction and the renin-angiotensin-aldosterone system, provides a synergistic and effective approach to lowering blood pressure.

It is crucial to take Azor exactly as your doctor prescribes and read the labeling information in the USA. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Azor, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Common side effects – These are some frequently reported side effects of Azor but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or if you experience any other concerning symptoms.
• Dizziness
• Swelling (edema), particularly in the ankles or feet
• Fatigue
• Headache
• Flushing (feeling of warmth and redness of the skin)
• Palpitations (feeling of rapid or irregular heartbeat)
• Nausea
• Indigestion (dyspepsia)

Serious Side Effects – Stop taking Azor and seek immediate medical attention if you experience any of the following:
• Severe allergic reactions: Symptoms may include rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing.
• Severe dizziness or lightheadedness: This could be a sign of excessively low blood pressure.
• Fainting (syncope)
• Chest pain or worsening (angina)
• Heart attack
• Kidney problems or changes in kidney function: Symptoms may include changes in urination.
• High potassium levels (hyperkalemia): Symptoms may include muscle weakness, irregular heartbeat.
• Sprue-enteropathy: Severe, chronic diarrhea with substantial weight loss.
• Jaundice: Yellowing of the skin or eyes (may indicate liver problems, although this is less commonly associated with these specific drugs).
• Severe low blood pressure (hypotension)

Individual reactions can vary. It is crucial to discuss potential side effects and risks with your doctor for a complete and up-to-date list.

Contraindications:

The following is not an exhaustive list of contraindications. It is crucial to discuss all of your medical conditions, past and present, and all the medications you are taking with your doctor or pharmacist before taking Azor (olmesartan)

Azor (olmesartan) should not be used in the following situations and should not be used if:
• Hypersensitivity: Azor is contraindicated in patients with known hypersensitivity to amlodipine besylate, olmesartan medoxomil, or any of the inactive ingredients in the formulation. Allergic reactions can range from mild to severe.
• Severe Hypotension: Azor should not be used in patients with severe hypotension (very low blood pressure) as it can further decrease blood pressure and lead to adverse outcomes.
• Shock (including cardiogenic shock): Patients in shock, including cardiogenic shock (where the heart is unable to pump enough blood to meet the body’s needs), should not take Azor.
• Obstruction of outflow tract of the left ventricle (e.g, severe aortic stenosis): Amlodipine can cause vasodilation, which may be poorly tolerated in patients with significant obstruction of the left ventricular outflow tract.

Drug Interactions:

Before taking Azor, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, consult the official Azor product monograph: https://azor.com/documents/41294/0/Azor.pdf

The following is a list of potential drug interactions:
• Other drugs that affect the Renin-Angiotensin System (RAS):
o Other Angiotensin II Receptor Blockers (ARBs): Co-administration is generally not recommended due to the potential for increased hypotension, hyperkalemia, and renal impairment.
o Angiotensin-Converting Enzyme Inhibitors (ACEIs): Similar to combining ARBs, using olmesartan with ACE inhibitors can increase the risk of hypotension, hyperkalemia, and renal impairment.
o Aliskiren: The combination of olmesartan with aliskiren, especially in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min), is contraindicated due to an increased risk of adverse cardiovascular and renal outcomes.
• Potassium-sparing diuretics (e.g., spironolactone, eplerenone), potassium supplements, or salt substitutes containing potassium: These can increase serum potassium levels, potentially leading to hyperkalemia, especially in patients with renal impairment.
• Nonsteroidal Anti-inflammatory Drugs (NSAIDs), including selective COX-2 inhibitors: NSAIDs can reduce the antihypertensive effect of ARBs and may increase the risk of renal impairment, particularly in elderly patients, volume-depleted patients, or those with compromised renal function.
• Lithium: Co-administration of lithium with ARBs may increase serum lithium concentrations and the risk of lithium toxicity. Monitoring of lithium levels is recommended.
• Colesevelam: Bile acid sequestrants like colesevelam can reduce the systemic exposure of olmesartan. Olmesartan should be administered at least 4 hours prior to colesevelam to minimize this interaction.

Interactions involving Amlodipine (Calcium Channel Blocker component):
• CYP3A4 Inhibitors: Amlodipine is metabolized by CYP3A4. Strong or moderate CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin, erythromycin, diltiazem, verapamil, grapefruit juice in large quantities) can significantly increase amlodipine exposure, potentially leading to increased hypotension and peripheral edema. Dose adjustment of amlodipine may be necessary.
• CYP3A4 Inducers: CYP3A4 inducers (e.g., rifampin, phenytoin, carbamazepine, St. John's Wort) can decrease amlodipine plasma concentrations, potentially reducing its antihypertensive effect. Caution is advised during co-administration.
• Simvastatin and Lovastatin: Co-administration of amlodipine with simvastatin or lovastatin can increase the systemic exposure of the statin, increasing the risk of myopathy and rhabdomyolysis. Lower starting and maintenance doses of the statin may be necessary.
• Digoxin: Amlodipine can increase digoxin levels. Monitoring of digoxin levels is recommended when starting, adjusting, or discontinuing amlodipine.
• Beta-blockers: Concomitant use may increase the risk of hypotension and bradycardia (slow heart rate). Caution and close monitoring are advised.
• Anaesthetics: Increased hypotensive effects may occur when calcium channel blockers are used with general anaesthetics.
• Alcohol: Excessive alcohol consumption can potentiate the hypotensive effects of amlodipine.

Interactions involving both components:
• Drugs that lower blood pressure: The antihypertensive effects of Azor can be additive with other blood pressure-lowering medications, increasing the risk of hypotension.

General Considerations:
• Patients with Renal Impairment: Caution is advised when using Azor with drugs that can affect renal function, as the risk of renal impairment may be increased.

Pregnancy or Breastfeeding:

If you are pregnant or planning to become pregnant, you should not take Azor. This medication contains olmesartan, which can seriously harm or even cause death to your unborn baby, especially during the second and third trimesters of pregnancy. If you find out you are pregnant while taking Azor, it’s important to stop taking it right away and talk to your doctor about other blood pressure medications that are safe to use during pregnancy.

The elderly:

Elderly individuals may be more likely to experience side effects like dizziness and low blood pressure, and their kidneys might not work as well. Doctors will usually start with a lower dose and check blood pressure and kidney function regularly. If you are an older adult taking Azor, be sure to tell your doctor about all your other medications and any side effects you experience, as they will want to ensure the medication is safe and effective for you.

Frequently Asked Questions about Azor at Canada Pharmacy Online:

Why is Azor more affordable in Canada than in the United States?

Prescription drug prices, including Azor, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations and differing market dynamics. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Azor tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Azor at one time, as per your doctor’s prescription.

Can I buy Azor over the counter from you?

No, Azor requires a prescription from your doctor. We are unable to sell this product without a valid prescription from your doctor.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Azor?

Yes, there is a generic alternative for this product called olmesartan medoxomil/amlodipine maleate.

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The generic alternative is not manufactured by the company that makes the brand product.

Similar Drugs in the category of Blood Pressure Medications (Calcium & Beta Blockers):

   Bystolic    Norvasc    Inderal    Tenormin    Toprol XL

This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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