Bezalip (Bezafibrate)

Name: Bezalip
Brand: Aralez Pharma
SKU: 5547
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Bezalip SR Tablet

Manufacturer: Aralez Pharma

Country: Canada

Dosage: 400 mg

Qty-Price (USD):

Generic Equivalent of Bezalip

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Bezafibrate (ON BACKORDER)

Manufacturer: Generic

Country: United Kingdom

Dosage: 400 mg

Qty-Price (USD):

Type:

Product: Bezafibrate SR Tablet

Manufacturer: Generic

Country: Canada

Dosage: 400 mg

Qty-Price (USD):

Bezalip Information

Bezalip and Bezafibrate SR at CanadaPharmacyOnline.com

The manufacturer of brand-name Bezalip SR (bezafibrate) is Aralez Pharma. It is available in many countries worldwide, including Canada.

Generic bezafibrate is also available from different manufacturers in the United Kingdom and Canada. The specific manufacturer of the dispensed medication may vary depending on pharmacy inventory. Generic bezafibrate is sourced from manufacturers that meet applicable regulatory standards.

Important Information about Generic Bezafibrate SR

Generic bezafibrate sustained-release tablets contain the same active ingredient as brand-name Bezalip SR. It must meet the same effectiveness and quality standards. This means it is designed to work like Bezalip. Studies have shown that generic bezafibrate is bioequivalent to brand-name Bezalip, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information on generic drug approval and bioequivalence, please visit “Access to Generic Drugs in Canada | Canada.ca”.

Dosage:

Bezalip SR (bezafibrate) is available in the following oral strengths at this pharmacy:
• Tablets: 400 mg sustained-release oral tablets.

Dosage is individualized and based on tolerability.

Usage:

Bezalip SR (bezafibrate) is a fibric acid derivative (fibrate) indicated as adjunctive therapy to diet for the reduction of elevated triglyceride levels (hypertriglyceridemia) and the treatment of mixed dyslipidemia (elevated triglycerides combined with low HDL cholesterol and elevated LDL cholesterol), in patients who have not responded adequately to diet alone. Bezafibrate may also help to reduce LDL cholesterol (the "bad" cholesterol) and raise HDL cholesterol (the "good" cholesterol), particularly in patients with hypertriglyceridemia.

Mechanism of Action
Bezafibrate primarily activates peroxisome proliferator-activated receptor alpha (PPAR-α), a nuclear receptor that regulates fat metabolism. This increases the activity of natural enzymes that clear triglycerides and “bad” cholesterol from your blood. It also reduces the liver's production of VLDL and free fatty acids. Through these and related mechanisms, bezafibrate lowers triglycerides, modestly lowers LDL cholesterol, and raises HDL cholesterol. The sustained-release formulation releases bezafibrate gradually, reducing the risk of gastrointestinal side effects compared to immediate-release formulations.

Take Bezalip SR exactly as your doctor prescribes, following the instructions in the package leaflet. Take once daily in the evening with or after the evening meal. Swallow whole. Do not crush, chew, or break the sustained-release tablet. If you miss a dose, take it as soon as you remember with a meal. However, if it is almost time for your next scheduled dose, skip the missed dose entirely. Never take a double dose to make up for a forgotten one. Dosage should be adjusted according to your doctor's instructions.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Bezalip, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Bezalip SR (bezafibrate). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Bezalip; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning.
• Nausea, vomiting, or stomach upset.
• Skin rash or itching
• Stomach pain or bloating

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Gallstones: Report any right upper abdominal pain, nausea after fatty meals, or jaundice.
• Muscle Damage: Unexplained muscle pain, weakness, or tenderness, particularly if accompanied by dark urine.
• Severe Allergic Reaction: Hives, swelling of the face, lips, tongue, or throat, or difficulty breathing.
• Worsening Kidney Function

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Bezalip, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Bezalip/bezafibrate if:
• Allergies: Known hypersensitivity to bezafibrate or other fibrates, or any ingredient in the tablet.
• Gallbladder Disease: Pre-existing gallstones or gallbladder disease.
• Liver Disease: Severe hepatic impairment or pre-existing liver disease, except for fatty liver secondary to hyperlipidemia.
• Pregnancy or breastfeeding.
• Severe Renal Impairment: Creatinine clearance below 60 mL/min.

Tell your doctor about all of your medical conditions, past and present, before starting Bezalip. This is crucial as certain conditions affect the drug's safety.
• Diabetes
• Kidney or liver disease
• Thyroid problems

Drug Interactions:

Before taking Bezalip, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the product monograph at https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/BEZALIP_SR_PM_EN.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Bezalip. Bezalip may interact with other medicines, including but not limited to:
• Antidiabetic agents (insulin and oral hypoglycemics): Bezafibrate may enhance their blood sugar-lowering effects. Monitor blood glucose closely.
• Bile acid sequestrants (e.g., cholestyramine): May reduce bezafibrate absorption. Administer Bezalip SR at least 2 hours before or after cholestyramine.
• Immunosuppressants (e.g., cyclosporine): Concurrent use may increase the risk of kidney damage and myopathy. Monitor renal function and creatine kinase.
• Statins (e.g., simvastatin, atorvastatin, rosuvastatin): Combining bezafibrate with a statin significantly increases the risk of myopathy and rhabdomyolysis. If the combination is clinically necessary, use the lowest effective statin dose and monitor closely for muscle symptoms.
• Warfarin and other oral anticoagulants: Bezafibrate potentiates warfarin's effect, increasing bleeding risk. Monitor INR closely and reduce the warfarin dose as needed when starting Bezalip.

Pregnancy and Breastfeeding:

Bezalip SR is contraindicated during pregnancy, as fibrates may cause harm to the developing baby. Women of childbearing potential should use effective contraception while taking Bezalip. Stop taking Bezalip if you become pregnant and consult your doctor. Bezalip is also contraindicated during breastfeeding, as bezafibrate may pass into breast milk.

Use in Children and Seniors:

The safety and efficacy of Bezalip SR in patients under 18 years of age have not been established. Bezalip SR is not recommended for use in children. Additionally, Bezalip SR is not recommended for adults over 70 due to age-related declines in kidney function.

Frequently Asked Questions about Bezalip at Canada Pharmacy Online

Why is Bezalip more affordable in Canada than in the United States?

Prescription drug prices, including Bezalip, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Bezalip I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of Bezalip per your doctor's prescription.

Can I buy Bezalip from you over the counter?

No, Bezalip requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Bezalip?

Yes, generic bezafibrate is available.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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