Calan (Verapamil)

Name: Calan
Brand: BGP Pharma
SKU: 6924
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Calan Tablet

Manufacturer: BGP Pharma

Country: New Zealand

Dosage: 40 mg

Qty-Price (USD):

Type:

Product: Calan Tablet

Manufacturer: BGP Pharma

Country: New Zealand

Dosage: 80 mg

Qty-Price (USD):

Generic Equivalent of Calan

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Verapamil Tablet

Manufacturer: Generic

Country: Canada

Dosage: 80 mg

Qty-Price (USD):

Type:

Product: Verapamil Tablet

Manufacturer: Generic

Country: Canada

Dosage: 120 mg

Qty-Price (USD):

Calan Information

Calan and Verapamil at CanadaPharmacyOnline.com

The manufacturer of brand-name Calan (verapamil) available at this pharmacy is BGP Pharma (New Zealand). Calan is also associated with the Isoptin brand distributed by Abbott and its successor companies. Knoll Pharmaceuticals originally developed the drug. BGP Pharma is a Viatris-associated entity.

Generic verapamil is also available and is produced by several reputable pharmaceutical companies that meet the rigorous standards of Health Canada and the FDA. Generic verapamil is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary based on current pharmacy stock.

Important Information about Generic Verapamil:

Generic verapamil hydrochloride tablets contain the same active ingredient as brand-name Calan. They must meet the same effectiveness and quality standards set by Health Canada. Studies have shown that generic verapamil is bioequivalent to brand-name Calan, meaning it has similar absorption and achieves plasma concentrations comparable to those of brand-name Calan. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Calan (verapamil hydrochloride) tablets are available in the following oral strengths and forms:
• Tablets: 40 mg, 80 mg, and 120 mg oral tablets

Dosage is individualized and depends on the condition being treated, the patient's response, and individual factors such as age and liver function. Take the tablets with food or milk if gastrointestinal upset occurs. Doses should be taken at evenly spaced intervals throughout the day.

Usage:

Calan (verapamil hydrochloride) immediate-release tablets are a phenylalkylamine-class calcium channel blocker indicated for three categories of cardiovascular conditions, including angina, arrhythmias, and high blood pressure. It is used to manage chronic stable angina and angina at rest. It is also used to slow down a dangerously racing pulse during rest or exercise in patients with chronic atrial fibrillation or atrial flutter. Calan effectively lowers blood pressure and can be used on its own or in combination with other blood pressure-lowering medications.

Mechanism of Action: Verapamil is a non-dihydropyridine calcium channel blocker belonging to the phenylalkylamine class. It is widely considered the most pharmacologically complex drug in its family. While other calcium channel blockers (like amlodipine) only target your outer blood vessels, verapamil works deeply in two distinct areas: the smooth muscle walls of your blood vessels and the physical tissues and electrical paths of your heart. It does this by blocking tiny cellular gateways called voltage-gated L-type calcium channels, preventing calcium from signaling these muscles to squeeze. Because it targets both areas, verapamil is highly effective in treating three distinct cardiovascular conditions, including chest pain, irregular rhythms, and hypertension.

Take Calan exactly as your doctor prescribes, following the instructions in the product monograph.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Calan, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Calan (verapamil hydrochloride). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Calan; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Bradycardia
• Constipation
• Dizziness
• Edema of the lower limbs
• Fatigue
• Flushing
• Headache
• Nausea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Blistering Skin Conditions: Seek emergency help immediately for rare, severe skin reactions like Stevens-Johnson syndrome or erythema multiforme.
• Liver Damage (Hepatotoxicity): Yellowing of your skin or eyes (jaundice), dark urine, severe pain in your upper right abdomen, a general feeling of being unwell (malaise), or an unexplained fever.
• Overgrowth of the Gums (Gingival Hyperplasia): This is a rare but known side effect of calcium channel blockers, where your gum tissue begins to swell or grow over your teeth.
• Severe Heart Electrical Blocks (AV Block or Asystole): Abnormally slow pulse, severe dizziness, light-headedness, or fainting.
• Severe Low Blood Pressure (Hypotension): Dizziness, feeling like you are about to pass out, lethargy, or profound weakness.
• Severe Swelling (Angioedema): Hives, a sudden rash, or immediate emergency signs like swelling of your face, lips, tongue, or throat, which can constrict your airways and make breathing or swallowing difficult.
• Worsening Heart Failure or Fluid in the Lungs (Pulmonary Edema): Sudden weight gain, increasing shortness of breath (especially when exerting yourself or trying to lie flat in bed), or worsening swelling in your ankles and legs.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Calan, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Calan/verapamil hydrochloride if you have:
• A recent heart attack that is complicated by a very slow heart rate, low blood pressure, or heart failure.
• Allergies: You have a known allergy or hypersensitivity to verapamil hydrochloride or to any of the inactive ingredients in the drug.
• Cardiogenic shock: A medical emergency where your heart muscle is suddenly too weak to pump enough blood to meet your body's basic needs.
• Severe low heart rate
• Second- or Third-Degree AV Block: You have a severe breakdown in your heart's internal electrical communication, except if you have a functioning pacemaker implanted.
• Severe low blood pressure
• Sick Sinus Syndrome: You have a pre-existing disorder in your heart's natural pacemaker cells, except if you have an implanted and functioning pacemaker.

Tell your doctor about all of your medical conditions, past and present, before starting Calan. Certain conditions require extra monitoring or dose adjustment.
• Digitalis toxicity
• First-degree AV Block
• Hypertrophic cardiomyopathy
• Kidney impairment
• Liver impairment
• Neuromuscular diseases, such as myasthenia gravis, Lambert-Eaton, and Duchenne Muscular Dystrophy

Drug Interactions:

Before taking Calan, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please refer to the product monograph at https://pdf.hres.ca/dpd_pm/00053488.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Calan. Calan may interact with other medicines, including but not limited to:
• Beta-Blockers: Combining oral verapamil with beta-blockers is generally not recommended. Using these medicines together increases the risk of severe slow heart rate (bradycardia), life-threatening heart block, and acute heart failure.
• Cyclosporine and Tacrolimus: Verapamil heavily blocks the specific systems (CYP3A4 and P-gp) used to clear these anti-rejection drugs. This causes their blood levels to spike, heavily increasing the risk of severe kidney damage.
• CYP3A4 Inducers (e.g., Rifampin, Phenobarbital, Phenytoin, Carbamazepine, St. John's Wort): act like an accelerator, forcing your liver to destroy verapamil much faster than normal. This causes the drug levels in your blood to plummet, making your blood pressure or heart rhythm control ineffective.
• CYP3A4 Inhibitors (e.g., Clarithromycin, Erythromycin, Itraconazole, Ketoconazole, Ritonavir, Cobicistat): shut down the liver pathway that clears verapamil, causing it to build to unsafe levels and increasing your risk of severe side effects.
• CYP3A4-Metabolized Statins (Simvastatin, Atorvastatin, Lovastatin): Verapamil blocks the breakdown of these specific statins, causing them to accumulate in your body.
• Digoxin: Verapamil reduces your body's ability to clear digoxin, causing it to build up to toxic levels (which can cause nausea, vision changes, and dangerous heart rhythms).
• Disopyramide: Do not take it within 48 hours before or 24 hours after taking verapamil. Combining them causes severe, dangerous depression of the heart muscle.
• Dofetilide: Verapamil spikes dofetilide levels in your blood, heavily increasing your risk of life-threatening ventricular heart rhythms.
• Grapefruit and Grapefruit Juice: contain natural compounds that temporarily shut down the CYP3A4 enzymes in your gut. This allows your body to absorb dangerous amounts of verapamil, which can trigger a severe drop in blood pressure accompanied by a dangerously slow heart rate.
• Other Antiarrhythmics (Amiodarone, Flecainide, Quinidine): These medications create an additive, depressive effect on your heart's pacing nodes and muscle strength.
• Other Antihypertensive Drugs & Vasodilators: Taking other blood pressure pills alongside Calan creates an additive effect that can drive your blood pressure down too low. Your doctor may need to adjust your dosages and closely monitor your blood pressure readings to ensure safety.

Pregnancy and Breastfeeding:

Calan is generally not recommended for use in pregnant women unless a specialist determines that the medical benefits to the mother clearly outweigh the potential risks to the fetus. If you are taking Calan and find out you are pregnant, or are planning to become pregnant, contact your doctor right away. Do not stop your medication abruptly, but work with them to see if you should transition to an alternative blood pressure medication with a more established pregnancy safety profile.

Verapamil is excreted into human breast milk in very low amounts. While it is generally considered compatible with nursing, you should consult your healthcare provider to weigh the risks and benefits for your specific situation. If you breastfeed while taking Calan, closely monitor your infant for excessive sleepiness, poor feeding, or a slow heart rate.

Use in Children:

The safety and effectiveness of oral Calan have not been established in children below 18 years of age.

Frequently Asked Questions about Calan at Canada Pharmacy Online

Why is Calan more affordable in Canada than in the United States?

Prescription drug prices, including Calan, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Calan I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Calan per prescription from your doctor.

Can I buy Calan from you over the counter?

No, Calan requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Calan?

Yes, generic verapamil tablets are available at this pharmacy.

Blog Post:

Natural Ways to Lower Your Blood Pressure

Latest News:

New obesity medications offer a potent tool for combating hypertension (study published May 15, 2026)

Similar Drugs in the category of Blood Pressure Medications (Calcium & Beta Blockers):

Bystolic Norvasc Inderal Tenormin Toprol XL

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers