Cozaar (Losartan)

Name: Cozaar
Brand: Organon
SKU: 0287
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Cozaar

Manufacturer: Organon

Country: Canada

Dosage: 25 mg

Qty-Price (USD):

Type:

Product: Cozaar

Manufacturer: Merck

Country: Turkey

Dosage: 50 mg

Qty-Price (USD):

Type:

Product: Cozaar

Manufacturer: Organon

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Cozaar

Manufacturer: Merck

Country: Turkey

Dosage: 100 mg

Qty-Price (USD):

Generic Equivalent of Cozaar

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Losartan

Manufacturer: Generic

Country: Canada

Dosage: 25 mg

Qty-Price (USD):

Type:

Product: Losartan

Manufacturer: Generic

Country: United Kingdom

Dosage: 25 mg

Qty-Price (USD):

Type:

Product: Losartan

Manufacturer: Generic

Country: Canada

Dosage: 50 mg

Qty-Price (USD):

Type:

Product: Losartan

Manufacturer: Generic

Country: United Kingdom

Dosage: 50 mg

Qty-Price (USD):

Type:

Product: Losartan

Manufacturer: Generic

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Losartan

Manufacturer: Generic

Country: United Kingdom

Dosage: 100 mg

Qty-Price (USD):

Cozaar Information

medically reviewed by Carol Hou (BSc. Pharm) on August 15, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Cozaar and Losartan at CanadaPharmacyOnline.com

The brand name Cozaar is manufactured by Organon in Canada and Merck in Turkey.

Generic Losartan is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Losartan:

Generic losartan contains the same active ingredient as brand-name Cozaar and must meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Cozaar. Studies have shown that generic losartan is bioequivalent to brand-name Cozaar, meaning they have similar absorption rates and reach similar concentrations in the bloodstream. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts

Dosage:

The brand Cozaar and generic losartan are commonly available in 25mg, 50mg, and 100mg oral tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Cozaar (losartan) is a prescription medication often used to help manage high blood pressure, which can reduce your risk of serious issues like stroke and heart attack. It belongs to a group of medicines that relax and widen your blood vessels, making it easier for your heart to pump blood throughout your body. Beyond high blood pressure, Cozaar is also prescribed to protect your kidneys if you have type 2 diabetes with kidney disease and high blood pressure, and to reduce the risk of stroke in people with high blood pressure and an enlarged heart.

Mechanism of Action:
Cozaar (losartan) exerts its therapeutic effects by specifically blocking the binding of angiotensin II to the angiotensin II type 1 (AT1) receptor. Angiotensin II, a potent vasoconstrictor produced by the renin-angiotensin-aldosterone system (RAAS), normally stimulates AT1 receptors to cause blood vessel constriction, increase aldosterone release (leading to sodium and water retention), and promote cardiac and vascular remodeling. By competitively inhibiting this binding, losartan prevents these detrimental actions, resulting in vasodilation, reduced systemic vascular resistance, decreased sodium and water reabsorption, and ultimately, reduced blood pressure. Its selectivity for the AT1 receptor, rather than the AT2 receptor, is crucial to its mechanism, allowing for adequate blood pressure control with a lower incidence of specific side effects than other RAAS-modulating agents.

Take Cozaar exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use. Consult your doctor for personalized guidance and safe use.

The information below summarizes, but does not list all, potential side effects, risks, and interactions. Before taking Cozaar, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side effects:

The information below outlines potential side effects of Cozaar (losartan). It is not an exhaustive list, and individual reactions can vary.

Common side effects – These are some common side effects of Cozaar, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Back pain
• Cough (less common than with ACE inhibitors)
• Diarrhea
• Dizziness (especially when standing up quickly)
• Fatigue or tiredness
• Headache
• Nasal congestion (stuffy nose)
• Upper respiratory infection (e.g., common cold symptoms)

Other Potential Side Effects (less common):
• Anemia.
• Depression.
• Edema (swelling).
• Impotence or decreased libido.
• Joint pain.
• Muscle pain or cramps.
• Ringing in the ears (tinnitus).
• Sleepiness.

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions (swelling of face, lips, tongue, throat; difficulty breathing).
• High Potassium levels (hyperkalemia).
• Hypotension (severely low blood pressure).
• Kidney problems.
• Liver problems.
• Seizures.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Cozaar, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Cozaar should not be used if you:
• Are allergic to losartan or any of its ingredients.
• Have diabetes and are also taking aliskiren.

Drug Interactions:

Before taking Cozaar, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the official Cozaar product monograph: https://www.organon.com/canada-en/wp-content/uploads/sites/5/2022/06/06/COZAAR-CI_E.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, or significant dietary changes, as these could interact with Cozaar. Cozaar may interact with other medicines, but is not limited to:
• ACE Inhibitors (e.g., benazepril, enalapril, lisinopril): Combining Cozaar with ACE inhibitors can increase the risk of serious side effects such as low blood pressure, high potassium levels (hyperkalemia), and kidney problems.
• Aliskiren: Co-administration with aliskiren is generally contraindicated, especially in patients with diabetes or kidney impairment, as it significantly increases the risk of hypotension, hyperkalemia, and renal dysfunction.
• Diuretics (Water Pills): Certain diuretics, especially potassium-sparing diuretics (e.g., amiloride, spironolactone, triamterene), can increase the risk of hyperkalemia when taken with Cozaar. Other diuretics may increase the risk of low blood pressure.
• Lithium: Cozaar can increase the levels of lithium in the blood, leading to a higher risk of lithium toxicity. Close monitoring of lithium levels is recommended.
• NSAIDs (Nonsteroidal Anti-Inflammatory Drugs), including COX-2 inhibitors (e.g., aspirin, ibuprofen, naproxen, celecoxib): NSAIDs can reduce the blood pressure-lowering effect of Cozaar and increase the risk of kidney problems, especially in elderly, dehydrated, or already renally impaired individuals.
• Potassium-containing supplements or salt substitutes: Since Cozaar can increase potassium levels, taking it with potassium supplements or salt substitutes containing potassium can lead to dangerously high potassium levels (hyperkalemia).

Pregnancy and Breastfeeding:

It's essential to know that Cozaar (losartan) should not be used if you are pregnant or plan to become pregnant, or if you are breastfeeding. Taking Cozaar during the second or third trimesters of pregnancy can cause severe harm or even be fatal to the developing baby, as it can significantly affect their kidney development. If you become pregnant while on Cozaar, it's crucial to stop the medication right away and contact your doctor for advice on safe alternatives. Similarly, it's generally recommended to avoid Cozaar while breastfeeding because it's uncertain if the medication passes into breast milk and could potentially affect your baby. Your healthcare provider can discuss safer options for managing your condition during this time.

Use in Children:

Cozaar (losartan) can be prescribed to children aged 6 years and older to treat high blood pressure, but it is not typically recommended for younger children. The dose for children is carefully determined by their doctor based on their weight to ensure it's safe and effective. It's important to note that Cozaar's use for conditions other than high blood pressure is generally for adults, and it may not be suitable for children with severe kidney or liver issues. Always speak with your child's doctor or a specialist to confirm if Cozaar is the proper medication for your child and to understand all specific instructions.

Frequently Asked Questions about Cozaar at Canada Pharmacy Online:

Why is Cozaar more affordable in Canada than in the United States?

Prescription drug prices, including Cozaar, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Does Losartan affect your body’s potassium levels?

Losartan can increase your potassium levels, which may affect your heart rhythm or reduce your mobility (source).

What is the best time of the day to take Losartan?

Losartan should be taken at about the same time each day to have the best effect; it does not matter whether you take it before or after food.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Cozaar tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Cozaar at once, as per your doctor's prescription.

Can I buy Losartan over the counter from you?

No, Losartan requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the difference between Cozaar 50 mg and 100 mg? The difference in dosage represents the amount of active ingredient(s) present in the drug.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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