Danuglipron (Danuglipron)

Name: Danuglipron
Brand: Pfizer
SKU: 7808
Availability: InStock

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Type:

Product: Danuglipron (UNAVAILABLE)

Manufacturer: Pfizer

Country: Canada

Dosage:

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Generic Equivalent of Danuglipron

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There is no generic product of Danuglipron.

Danuglipron Information

Danuglipron at CanadaPharmacyOnline.com

Danuglipron (PF-06882961) is an experimental medication whose development was discontinued by Pfizer Inc. in April 2025 due to safety concerns (including potential liver injury) and tolerability issues. This drug is NOT approved, manufactured, or available for sale anywhere in the world, including Canada. Generic danuglipron is currently unavailable (at this pharmacy).

Usage:

Danuglipron (danuglipron) was an investigational medicine that has not yet been approved by the U.S. Food and Drug Administration (FDA) or any other significant health authority for sale or use. The information below is based on data from clinical trials and characteristics typical of its drug class. Danuglipron was investigated primarily for the treatment of Type 2 Diabetes Mellitus (T2D) and Obesity (weight management). Type 2 diabetes is a long-term condition where the body struggles to use insulin properly or doesn't make enough of it, causing high blood sugar levels. Obesity happens when the body has too much fat, which can lead to serious health issues. Danuglipron is an oral medication being developed to help people lower their blood sugar and lose weight.

Mechanism of Action:
Danuglipron (danuglipron) is an agonist for the Glucagon-like peptide-1 (GLP-1) receptor. GLP-1 is a natural hormone that controls both appetite and blood sugar. By targeting this receptor, Danuglipron can help the pancreas release more insulin when blood sugar is high and reduce the production of glucagon, a hormone that raises blood sugar. It also slows down digestion, allowing food to be absorbed more gradually. This makes you feel fuller, helps you eat less, and supports weight loss.

As this medication was never approved, a final Product Monograph (Prescribing Information) was never issued. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Danuglipron, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with Danuglipron (danuglipron). It is not an exhaustive list, and individual reactions can vary. This information is for educational purposes and should not replace professional medical advice. Before starting Danuglipron, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - The following are some common side effects of Danuglipron; others may occur. Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms.
• Abdominal pain;
• Constipation;
• Diarrhea;
• Nausea;
• Vomiting

Serious or rare side effects- Seek immediate medical attention or call emergency services if you experience any of the following:
• Acute Pancreatitis: Symptoms can include severe, persistent abdominal pain that may radiate to the back, with or without vomiting. Discontinue use of the drug if pancreatitis is suspected.
• Hypoglycemia (Low Blood Sugar): The risk is increased when Danuglipron is used in combination with other anti-diabetic medications that lower blood sugar, such as sulfonylureas or insulin.
• Severe Dehydration and Acute Kidney Injury: Severe gastrointestinal side effects, such as persistent vomiting and diarrhea, can lead to fluid loss and dehydration. In severe cases, this can lead to worsening kidney function or acute kidney injury.
• Hypersensitivity Reactions: Severe allergic reactions, such as anaphylaxis and angioedema.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Danuglipron, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Danuglipron should not be used if:
• You have a known allergy to danuglipron or any of the ingredients in the medication.
• You have a history of pancreatitis.
• You have type 1 diabetes or diabetic ketoacidosis.

Tell your doctor about all of your medical conditions, past and present, before starting Danuglipron. This is crucial because certain conditions can affect whether Danuglipron is right for you. These conditions may include, but are not limited to:
• A history of allergic reactions to other medications.
• A personal or family history of thyroid C-cell tumors or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Drug Interactions:

Before taking Danuglipron, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Patient Information.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Danuglipron. Because Danuglipron was discontinued before final approval, official drug interaction guidance is limited. Danuglipron may interact with other medicines, but is not limited to:
• Drugs that slow digestion or affect absorption – Medications such as certain antacids, proton pump inhibitors, or other drugs that affect gastric emptying could alter how Danuglipron is absorbed.
• Oral medications sensitive to blood sugar changes – Some drugs, like certain antibiotics or heart medications, may have altered effects if blood sugar levels change significantly.
• Other diabetes medications – Drugs like insulin, sulfonylureas, or other GLP-1 receptor agonists could increase the risk of low blood sugar (hypoglycemia) when used with Danuglipron.

Pregnancy and Breastfeeding:
Danuglipron is an investigational drug, and there are no adequate and well-controlled studies in pregnant women. Based on the mechanism of action and animal reproduction studies of similar medications, Danuglipron is expected to cause fetal harm when administered during pregnancy. It should only be used if the potential benefit justifies the potential risk to the fetus. Women of reproductive potential should discuss effective contraception with their healthcare provider. It is currently unknown whether Danuglipron is excreted in human breast milk or what effects it might have on a breastfed infant. Due to the potential for severe adverse reactions in the infant, discuss whether to discontinue nursing or discontinue the drug with your doctor.

Hydration:
Drink plenty of fluids if you experience nausea, vomiting, or diarrhea, to prevent dehydration and potential kidney complications.

Frequently Asked Questions about Danuglipron at Canada Pharmacy Online:

Why is Danuglipron more affordable in Canada than in the United States?

Prescription drug prices, including Danuglipron, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is committed to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Danuglipron at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Danuglipron requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It typically takes 7-18 business days to receive your order from our pharmacy.

Is Danuglipron currently approved and available for purchase?

No. Danuglipron is an abandoned investigational drug (PF-06882961). Pfizer discontinued all development of this drug. It is not approved, manufactured, or available for commercial sale.

When is Danuglipron expected to be available?

Danuglipron will not be commercially available. Pfizer has officially discontinued its development. There is no expected timeline for approval or launch.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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