Diamox (Acetazolamide)

Name: Diamox
Brand: Brand
SKU: 0015
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Diamox

Manufacturer: Brand

Country: India

Dosage: 250 mg

Qty-Price (USD):

Generic Equivalent of Diamox

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Acetazolamide

Manufacturer: Generic

Country: Canada

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Acetazolamide

Manufacturer: Generic

Country: United Kingdom

Dosage: 250 mg

Qty-Price (USD):

Diamox Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on September 11, 2025.

Diamox and Acetazolamide at CanadaPharmacyOnline.com

The brand name Diamox, manufactured by Pfizer, is available in India.

Generic acetazolamide is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important information about Generic Acetazolamide:

Generic acetazolamide contains the same active ingredient as brand-name Diamox and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Diamox. Studies have shown that generic acetazolamide is bioequivalent to brand-name Diamox, meaning they have similar absorption rates and reach similar concentrations in the bloodstream. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts.

Dosage:

The brand Diamox and acetazolamide are commonly available in the strength of 250 mg oral tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Diamox (acetazolamide) is a versatile medication primarily used to lower high pressure within the eye, making it a key treatment for various forms of glaucoma. Beyond eye conditions, it also acts as a diuretic, helping your body eliminate excess fluid and salt, which can help manage edema (swelling), especially related to heart failure. For those traveling to high elevations, Diamox is often prescribed to prevent or reduce symptoms of altitude sickness, aiding in faster acclimatization. Additionally, it can serve as an add-on treatment for certain types of epilepsy (seizures) and to decrease elevated pressure around the brain in a condition called idiopathic intracranial hypertension.

Mechanism of Action:
Diamox (acetazolamide) mainly works by blocking the enzyme carbonic anhydrase, which exists in many tissues throughout the body. In the kidneys, this blockage causes less bicarbonate, sodium, and water reabsorption, leading to a diuretic effect and causing mild metabolic acidosis. In the eye, it decreases the production of aqueous humor in the ciliary body, which lowers intraocular pressure and helps in glaucoma. Additionally, increasing metabolic acidosis encourages breathing, helping acclimate to high altitudes. In the brain, it lowers cerebrospinal fluid production, aiding in reducing intracranial pressure in conditions like idiopathic intracranial hypertension, and its effect on neuronal excitability is believed to help with its anticonvulsant properties.

Take Diamox exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Diamox, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Diamox (acetazolamide). It is not an exhaustive list, and individual reactions can vary.

Common side effects – These are common side effects of Diamox, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Altered taste (especially metallic or bitter, or changes in how carbonated drinks taste)
• Dizziness
• Drowsiness
• Fatigue or tiredness
• Headache
• Increased urination
• Loss of appetite
• Nausea
• Numbness or tingling (paresthesias), especially in the fingers, toes, and around the mouth
• Ringing in the ears (tinnitus)
• Vomiting

Other Potential Side Effects (less common):
• Anemia (low red blood cell count)
• Confusion
• Depression
• Diarrhea
• Dry mouth
• Increased thirst
• Itchy skin rash or hives
• Muscle pain or cramps
• Sensitivity to sunlight (photosensitivity)
• Temporary shortsightedness (myopia)
• Weakness

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions (e.g., severe skin rashes like Stevens-Johnson syndrome or toxic epidermal necrolysis, blistering, peeling skin, fever, sore throat, swelling of face, lips, tongue, or throat, difficulty breathing, hives, itching)
• Blood disorders (e.g., aplastic anemia, agranulocytosis, thrombocytopenia, leading to unusual bleeding, bruising, frequent infections, pale skin)
• Electrolyte imbalances (e.g., severe metabolic acidosis, low potassium, low sodium, which can cause confusion, irregular heartbeat, muscle weakness)
• Kidney problems (e.g., kidney stones, impaired renal function, renal failure, blood in urine, painful urination, lower back pain)
• Liver problems (e.g., liver failure, hepatitis, symptoms like dark urine, pale stools, yellowing of skin or eyes, severe upper stomach pain, persistent nausea/vomiting)
• Seizures (if used for epilepsy, sudden discontinuation can worsen seizures)
• Suicidal thoughts or behaviors (rare, but possible with anti-epileptic agents)
• Vision problems (e.g., sudden decrease in vision, eye pain, choroidal effusion/detachment)

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Diamox, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Diamox should not be used if you have any of the following conditions:
• Adrenal gland failure (Addison's disease).
• Cirrhosis of the liver or severe liver disease, as it may precipitate hepatic encephalopathy.
• A known hypersensitivity to acetazolamide, other sulfonamides, or any medication components.
• Significant kidney disease or severe renal dysfunction (e.g., severe impaired creatinine clearance), as it can worsen acidosis.
• Low sodium levels in your blood (hyponatremia).
• Low potassium levels in your blood (hypokalemia).
• Long-term (chronic non-congestive) angle-closure glaucoma, as it could lead to further vision loss due to angle closure.
• Marked emphysema or chronic obstructive pulmonary disease (COPD) with respiratory acidosis.
• Severe metabolic acidosis.

Drug Interactions:

Before taking Diamox, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the official Diamox product monograph: https://www.aapharma.ca/downloads/en/PIL/2021/Acetazolamide_PM_EN.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, or significant dietary changes, as these could potentially interact with Diamox. Diamox may interact with other medicines, but is not limited to:
• Amphetamines: Diamox can increase the pH of urine, which reduces the excretion of amphetamines (and other basic drugs). This can lead to increased levels and effects of amphetamines in the body.
• Aspirin and other Salicylates (including high-dose aspirin): This is a significant interaction. Concomitant use with Diamox, especially high-dose aspirin, can lead to increased levels of both drugs due to competition for renal excretion. This can result in serious side effects like severe metabolic acidosis, central nervous system toxicity (e.g., lethargy, coma), anorexia, and rapid breathing. This combination is generally avoided or used with extreme caution and close monitoring.
• Carbonic Anhydrase Inhibitors (other): Using Diamox with other carbonic anhydrase inhibitors (e.g., methazolamide, dorzolamide, brinzolamide) is generally not recommended due to the potential for additive effects and increased risk of side effects.
• Cyclosporine: Diamox may increase the blood levels of cyclosporine, a medication used to suppress the immune system. This could lead to increased side effects from cyclosporine.
• Diuretics (other): When used with other diuretics, Diamox can have additive effects on fluid and electrolyte balance, potentially increasing the risk of dehydration, low potassium (hypokalemia), or low sodium (hyponatremia).
• Drugs that cause potassium loss: Medications such as corticosteroids or certain laxatives, when used with Diamox, can increase the risk of developing low potassium levels.
• Lithium: Diamox can increase lithium excretion, which may lead to decreased lithium levels and reduced effectiveness of lithium. Monitoring of lithium levels is often necessary.
• Memantine: Diamox can affect the elimination of memantine from the body, potentially altering its effects.
• Methenamine: Diamox's effect of alkalinizing the urine can prevent methenamine from working effectively as a urinary antiseptic, as methenamine requires an acidic urine environment to be active.
• Phenytoin, Primidone, and Quinidine: Diamox can decrease the excretion of these medications, potentially leading to increased blood levels and a higher risk of toxicity or side effects. Close monitoring may be required.
• Sodium Bicarbonate: Concurrent use with sodium bicarbonate can increase the risk of kidney stone formation.
• Topiramate and Zonisamide: These are other carbonic anhydrase inhibitors, and combining them with Diamox can increase the risk of metabolic acidosis and other side effects due to additive effects.

Pregnancy and Breastfeeding:

It's essential to be aware that Diamox (acetazolamide) is generally not recommended if you are pregnant or breastfeeding. For pregnancy, particularly during the first trimester, there's a concern about potential risks based on animal studies, so it should only be considered if the benefits outweigh the potential harm to the baby. If you become pregnant while taking Diamox, you should inform your doctor right away. While acetazolamide does pass into breast milk in small amounts, it's typically advised to avoid using it during breastfeeding due to the potential for side effects in the infant. Your healthcare provider can discuss the risks and help you decide on the safest approach for your situation.

Frequently Asked Questions about Diamox at Canada Pharmacy Online:

Why is Diamox more affordable in Canada than in the United States?

Prescription drug prices, including Diamox, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Diamox tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of three months of Diamox at once, as per your doctor's prescription.

Can I buy Diamox over the counter from you?

No, Diamox requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for Diamox?

Yes, there is a generic alternative for this product, called Acetazolamide.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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