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Duralith (Lithium Carbonate)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no brand product of Duralith.

Generic Equivalent of Duralith
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Lithium Carbonate Capsule
Manufacturer: Generic
Country: Canada
Dosage: 150 mg
Qty-Price (USD):
Type: drug type
Product: Lithium Carbonate Capsule (ON BACKORDER)
Manufacturer: Generic
Country: Canada
Dosage: 300 mg
Qty-Price (USD):
Type: drug type
Product: Lithium Carbonate Sustained-Release Tablets
Manufacturer: Generic
Country: Canada
Dosage: 300 mg
Qty-Price (USD):

Duralith Information

Duralith and Lithium carbonate at CanadaPharmacyOnline.com

The manufacturer of brand-name Duralith is Janssen Inc. (a pharmaceutical company of Johnson & Johnson). Duralith is a long-established medication used to stabilize mood. In Canada, Duralith is one of the primary brand names for controlled-release lithium carbonate. The brand Duralith is currently unavailable (at this pharmacy).

While the brand-name version is a frequent choice, generic lithium carbonate (controlled-release) is produced by several manufacturers that meet Health Canada's strict quality and safety standards. Common generic producers include Apotex (Apo-Lithium CL) and Euro-Pharm (Lithane). Generic lithium carbonate is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary based on current pharmacy stock.

Important Information about Generic Lithium Carbonate

Generic lithium carbonate contains the same active ingredient as brand-name Duralith. It must meet the same effectiveness and quality standards. This means it is designed to work like Duralith. Studies have shown that generic lithium carbonate is bioequivalent to brand-name Duralith, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Generic lithium carbonate is available in the following strengths and forms:
• Capsule: 150 mg and 300 mg
• Tablets: 300 mg sustained-release tablets

The dosage of Duralith is highly individualized and based on blood lithium levels and the patient's clinical response. A common starting dose for adults is 600 mg to 900 mg per day, divided into two or three doses. Your doctor will frequently monitor your blood to ensure the dose remains within a narrow "therapeutic window."

Usage:

Duralith is primarily used to treat and prevent episodes of mania in people with bipolar disorder (manic-depressive illness). At the correct levels, it helps reduce the intensity and frequency of manic episodes, which may involve symptoms like extreme excitement, rapid speech, decreased need for sleep, and poor judgment. It is also used as a maintenance therapy to prevent or lessen the intensity of future manic or depressive episodes. Duralith is intended for long-term use and should not be stopped without close medical supervision.

Mechanism of Action
Lithium carbonate, the active ingredient in Duralith, helps restore the balance of certain natural chemicals in the brain. It is an antimanic agent that alters how nerve cells respond to chemical messengers (neurotransmitters), such as serotonin and norepinephrine, which are involved in mood regulation. It may help strengthen nerve cell connections in brain regions that are involved in regulating emotions. By adjusting the "signaling" within brain cells, it helps prevent the overactivity that leads to manic states and the underactivity that leads to depressive states.

Take Duralith exactly as your doctor prescribes, following the product monograph. It is important to maintain a consistent intake of salt and water while taking this medication, as changes in your salt or fluid levels can cause lithium levels in your blood to rise to dangerous levels.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Duralith, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Duralith (lithium carbonate). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Duralith; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Increased thirst and frequent urination
• Mild hand tremors
• Nausea or diarrhea
• Weight gain or mild fatigue

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Confusion or seizures
• Extreme drowsiness or muscle weakness
• Hypothyroidism (with long-term use)
• Lack of coordination or significant "shaking" (tremors)
• Severe nausea, vomiting, or persistent diarrhea
• Slurred speech or blurred vision

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Duralith, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Duralith/lithium carbonate if:
• Allergies: You have a known hypersensitivity to lithium carbonate or other lithium salts.

Tell your doctor about all of your medical conditions, past and present, before starting Duralith. This is crucial as certain conditions affect the drug's safety.
• Heart Disease: Especially conditions that affect heart rhythm.
• Kidney Disease: Since the kidneys clear lithium, significant kidney impairment may make this drug unsafe.
• Severe Dehydration: Or conditions that cause low sodium levels.

Drug Interactions:

Before taking Duralith, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the consumer medicine information at https://www.medsafe.govt.nz/consumers/cmi/l/LithiumCarbonate.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Duralith. Duralith may interact with other medicines, including but not limited to:
• ACE Inhibitors: Certain blood pressure medications (e.g., ramipril, lisinopril).
• Diuretics: (Water pills) like hydrochlorothiazide.
• NSAIDs: Common pain relievers like ibuprofen (Advil/Motrin) or naproxen (Aleve).

Pregnancy and Breastfeeding:

Duralith is not recommended during pregnancy, as it can cause harm to a fetus, specifically heart defects (Ebstein's anomaly), if taken during the first trimester. Discuss the risks and benefits thoroughly with your doctor. Lithium passes into breast milk and can cause toxicity in the infant. Breastfeeding is generally not recommended while taking this medication.

Use in Children:

The safety and effectiveness of Duralith in children under 12 years of age have not been fully established. Use in adolescents must be closely monitored by a specialist.

Frequently Asked Questions about Duralith at Canada Pharmacy Online

Why is Duralith more affordable in Canada than in the United States?

Prescription drug prices, including Duralith, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Duralith tablets I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Duralith per prescription from your doctor.

Can I buy Duralith from you over the counter?

No, Duralith requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Duralith?

Yes, there is a generic alternative to Duralith: lithium carbonate.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
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