Isoniazid Syrup (Isoniazid)

Name: Isoniazid Syrup
Brand: Generic
SKU: 7315
Availability: InStock

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Qty-Price (USD)

There is no brand product of Isoniazid Syrup.

Generic Equivalent of Isoniazid Syrup

Type

Product

Manufacturer

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Qty-Price (USD)

Type:

Product: Isoniazid

Manufacturer: Generic

Country: Canada

Dosage: 50 mg/5 ml/500 ml

Qty-Price (USD):

Isoniazid Syrup Information

Isonazid at CanadaPharmacyOnline.com

The manufacturer of Isoniazid Syrup (oral solution) varies by product and region. In Canada, it has traditionally been available under brand names like Isotamine or marketed by companies such as PDP-Isoniazid (distributed by Pendopharm) and PMS-Isoniazid (Pharmascience). In the United States, CMP Pharma is the only manufacturer of the FDA-approved isoniazid oral solution.

Generic isoniazid is produced by several manufacturers that meet strict regulatory standards for safety and quality. Generic isoniazid is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Isoniazid Syrup

Generic isoniazid contains the same active ingredient as brand-name Isoniazid Syrup. It must meet the same effectiveness and quality standards. This means it is designed to work like Isoniazid Syrup. Studies have shown that generic Isoniazid Syrup is bioequivalent to brand-name Isoniazid Syrup, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Isoniazid is available in the following common strengths:
• Syrup: 50 mg/5 mL in a 500 mL bottle

Dosage is determined by a doctor based on the patient's weight, age, and whether they are being treated for active or latent tuberculosis (TB). For children, the usual dose is 10 to 20 mg/kg body weight per day.

Usage:

Isoniazid is a specialized antibiotic used to treat and prevent tuberculosis (TB), a serious infection primarily affecting the lungs. It is considered a first-line treatment and is often used in combination with other medications, such as rifampin and pyrazinamide, to ensure that all bacteria are eliminated. For patients with active TB, it helps clear the infection. For those with latent TB (where bacteria are present but not causing symptoms), it prevents the infection from becoming active. It is important to note that isoniazid only treats bacterial infections; it will not work for viral illnesses like the common cold or flu. Completing the full course of treatment, which can last from 6 months to 2 years, is essential to prevent the bacteria from becoming resistant to antibiotics.

Mechanism of Action
Isoniazid is a prodrug, meaning it must be activated inside the body to exert its effects. Once it enters the Mycobacterium tuberculosis cells, it is activated by a bacterial enzyme called catalase-peroxidase (KatG). The activated drug then targets and inhibits the synthesis of mycolic acids, which are essential components of the bacterial cell wall. Without these acids, bacteria cannot maintain the integrity of their cell walls, leading to weakening and eventual death. This bactericidal (bacteria-killing) action is most effective against actively dividing and growing bacteria. By targeting a structural component unique to mycobacteria, isoniazid provides a powerful, selective treatment for tuberculosis.

Take isoniazid exactly as your doctor prescribes, following the instructions in the prescribing information. For best absorption, it should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Isoniazid Syrup, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Isoniazid Syrup (isoniazid). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Isoniazid Syrup; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Dizziness
• Loss of appetite
• Nausea or vomiting
• Stomach pain or diarrhea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Severe allergic reaction involving swelling of the face, tongue, or throat and difficulty breathing.
• Liver Problems: Yellowing of the eyes/skin (jaundice), dark urine, or severe upper stomach pain.
• Nerve Damage (Peripheral Neuropathy): Numbness, tingling, or burning pain in the hands or feet.
• Seizures: Especially in patients with a history of epilepsy.
• Vision Changes: Pain behind the eyes or blurred vision.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Isoniazid Syrup, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Isoniazid Syrup/Isoniazid if:
• Active Liver Disease: You have current hepatitis or severe liver issues.
• Allergies: You have a known hypersensitivity to isoniazid.
• History of Liver Injury: You previously experienced liver problems or severe side effects caused by isoniazid.

Tell your doctor about all of your medical conditions, past and present, before starting Isoniazid Syrup. This is crucial as certain conditions affect the drug's safety.
• Alcohol Use: Daily alcohol consumption significantly increases the risk of liver damage while taking this medicine.
• Diabetes: Isoniazid can affect blood sugar levels and may cause false results with some urine sugar tests.
• Kidney Disease: Your doctor may need to monitor your dosing schedule more closely.
• Recent Childbirth: Women who have recently given birth may be at a higher risk for liver problems during treatment.

Drug Interactions:

Before taking Isoniazid Syrup, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the prescribing information at https://pdf.hres.ca/dpd_pm/00058753.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Isoniazid Syrup. Isoniazid Syrup may interact with other medicines, including but not limited to:
• Acetaminophen (Tylenol): Taking these together increases the stress on your liver.
• Antacids: Products containing aluminum can block the absorption of isoniazid. Take isoniazid at least 1 hour before antacids.
• Foods to Avoid: High-tyramine or high-histamine foods (such as aged cheese, red wine, and certain fish like tuna) can trigger a reaction that leads to high blood pressure or a racing heart.
• Seizure Medications: Isoniazid can increase the levels of phenytoin (Dilantin) or carbamazepine in your blood.

Pregnancy and Breastfeeding:

Isoniazid is generally considered safe during pregnancy when the benefits outweigh the risks. However, pyridoxine (vitamin B6) supplementation is usually required to prevent nerve damage. Small amounts of this medication pass into breast milk, and nursing infants should also receive vitamin B6 supplementation while the mother is on this medication. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

Isoniazid is frequently used in pediatric patients. Pediatricians calculate the dose based on the child's weight to ensure effective treatment while minimizing the risk of side effects.

Frequently Asked Questions about Isoniazid Syrup at Canada Pharmacy Online

Why is Isoniazid Syrup more affordable in Canada than in the United States?

Prescription drug prices, including Isoniazid Syrup, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Isoniazid Syrup I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Isoniazid Syrup per prescription from your doctor.

Can I buy Isoniazid Syrup from you over the counter?

No, Isoniazid Syrup requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Isoniazid Syrup?

Yes, there is a generic alternative to Isoniazid Syrup: isoniazid.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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