Lixiana (Edoxaban Tosylate)

Name: Lixiana
Brand: Generic
SKU: 7510
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no brand product of Lixiana.

Generic Equivalent of Lixiana

Type

Product

Manufacturer

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Type:

Product: Edoxaban Tosylate Tablet

Manufacturer: Generic

Country: Canada

Dosage: 15 mg

Qty-Price (USD):

Type:

Product: Edoxaban Tosylate Tablet

Manufacturer: Generic

Country: Canada

Dosage: 30 mg

Qty-Price (USD):

Type:

Product: Edoxaban Tosylate Tablet

Manufacturer: Generic

Country: Canada

Dosage: 60 mg

Qty-Price (USD):

Lixiana Information

Edoxaban tosylate at CanadaPharmacyOnline.com

The manufacturer of Lixiana (edoxaban) is relatively consistent globally, as the drug was developed by the Japanese pharmaceutical company Daiichi Sankyo. In Canada, the brand-name Lixiana is marketed and distributed by Servier Canada Inc. under license from Daiichi Sankyo. In the United Kingdom and much of Europe, it is marketed directly by Daiichi Sankyo Europe GmbH.

In the United States, edoxaban is sold under the brand name Savaysa and marketed by Daiichi Sankyo, Inc. While the brand names differ by region (Lixiana vs. Savaysa), they contain the same active ingredient. Generic edoxaban is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturers of your dispensed medication may vary.

The brand Lixiana is currently unavailable (at this pharmacy).

Important Information about Generic Edoxaban Tosylate

Generic edoxaban tosylate contains the same active ingredient as brand-name Lixiana. It must meet the same effectiveness and quality standards. This means it is designed to work in the same way as Lixiana. Studies have shown that generic edoxaban tosylate is bioequivalent to brand-name Lixiana, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Generic edoxaban tosylate is available in strengths of 15 mg, 30 mg, and 60 mg tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Lixiana is an anticoagulant (blood thinner) primarily used to prevent stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF) who have one or more risk factors. NVAF is a heart rhythm disorder in which the upper chambers of the heart beat irregularly and ineffectively. Because blood does not flow smoothly, it can pool inside the heart and form clots. These clots can travel to the brain or other organs, causing a stroke or systemic embolism. It is also used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE), and to prevent recurrence. DVT occurs when a blood clot forms in a deep vein, most commonly in the legs. PE is a potentially life-threatening condition that happens when a blood clot, often originating from a DVT, blocks an artery in the lungs.

Mechanism of Action
Lixiana is a direct factor Xa inhibitor. It works by blocking a key step in the body’s blood-clotting process. It targets a substance called factor Xa, which plays an essential role in the formation of thrombin, a protein needed to form blood clots.

By attaching to factor Xa, Lixiana stops thrombin from being produced. With less thrombin available, the body cannot form the fibrin strands that act like the “glue” holding a blood clot together. This helps prevent harmful clots from forming or growing.

Because Lixiana acts on a specific part of the clotting system, its effects are more predictable. As a result, most people taking it do not need frequent blood tests to adjust their dose, unlike older blood thinners such as warfarin.

Take Lixiana exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Lixiana, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Lixiana (edoxaban tosylate). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Lixiana; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Anemia
• Bleeding gums or unusual bruising
• Blood in urine
• Nosebleeds

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Swelling of the face or throat, hives, or extreme difficulty breathing.
• Severe bleeding: Any bleeding that will not stop, red or black tarry stools, or coughing up blood.
• Signs of stroke: Sudden numbness or weakness (especially on one side of the body), sudden confusion, or trouble speaking.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Lixiana, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Lixiana/edoxaban tosylate if:
• Active bleeding: You have clinically significant active bleeding (e.g., a stomach ulcer)
• Liver disease: You have liver disease associated with blood-clotting issues
• Other anticoagulants: You are already taking another blood thinner, unless you are in the process of switching medications
• Pregnancy and breastfeeding: Lixiana is contraindicated during pregnancy and while nursing.

Tell your doctor about all of your medical conditions, past and present, before starting Lixiana. This is crucial as certain conditions affect the drug’s safety.
• Body weight: Patients weighing 60 kg (132 lbs) or less may require a reduced dose.
• High blood pressure: Uncontrolled hypertension increases the risk of intracranial bleeding.
• Kidney problems: Edoxaban is cleared by the kidneys. A high or very low clearance rate may require a dose adjustment or make the drug unsuitable.

Drug Interactions:

Before taking Lixiana, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the practical guide from Daiichi-Sankyo at https://www.lixiana.com/en/-/media/www,-d-,lixiana,-d-,com/Documents/practical-guide.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Lixiana. Lixiana may interact with other medicines, including but not limited to:
• NSAIDs: Common pain relievers like aspirin, ibuprofen, or naproxen can significantly increase bleeding risk.
• P-gp Inhibitors: Medications like erythromycin, cyclosporine, or ketoconazole can increase Lixiana levels in the blood.
• SSRIs/SNRIs: Certain antidepressants can increase the risk of bleeding when taken with anticoagulants.

Pregnancy and Breastfeeding:

Lixiana (edoxaban tosylate) is strictly contraindicated during pregnancy. Use effective contraception to prevent pregnancy when taking Lixiana. The medicine passes into breast milk and is not advised when breastfeeding. Inform your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

Use in Children:

The safety and effectiveness of Lixian in children and adolescents under 18 years of age have not been established. The medication is strictly for use in adults.

Frequently Asked Questions about Lixiana at Canada Pharmacy Online

Why is Lixiana more affordable in Canada than in the United States?

Prescription drug prices, including Lixiana, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Lixiana I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Lixiana per prescription from your doctor.

Can I buy Lixiana over the counter from you?

No, Lixiana requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Lixiana?

Yes, there is a generic alternative to Lixiana: Edoxaban tosylate.

Blog Post:

A Silent but Rising Threat: Why More Young Adults Are Getting Blood Clots

Latest News:

Continuous anticoagulation may reduce thromboembolic events in patients with trauma (article published on December 30, 2025)

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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