Lupron Depot (Leuprolide Acetate)

Name: Lupron Depot
Brand: Abbvie
SKU: 1643
Availability: InStock

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Qty-Price (USD)

Type:

Product: Lupron Depot

Manufacturer: Abbvie

Country: Canada

Dosage: 3.75 mg

Qty-Price (USD):

Type:

Product: Lupron Depot

Manufacturer: Abbvie

Country: Canada

Dosage: 7.5 mg

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Type:

Product: Lupron Depot

Manufacturer: Abbvie

Country: Canada

Dosage: 11.25 mg

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Product: Lupron Depot

Manufacturer: Abbvie

Country: Canada

Dosage: 22.5 mg

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Type:

Product: Lupron Depot

Manufacturer: Abbvie

Country: Canada

Dosage: 30 mg

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Generic Equivalent of Lupron Depot

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There is no generic product of Lupron Depot.

Lupron Depot Information

medically reviewed by Carol Hou (BSc. Pharm) on April 25, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Lupron Depot at CanadaPharmacyOnline.com

Lupron Depot (leuprolide Acetate) is manufactured by AbbVie and is available in Canada and Turkey.

There might be a generic version is available in the market. But currently it is NOT in stock in this pharmacy.

Dosage:

Brand Lupron Depot is available as an injection suspension, in strengths of 3.75 mg, 7.5 mg, 11.25 mg, 22.5 mg, and 30 mg.

Your doctor will determine your safe and effective dosage based on your individual needs.

Usage:

Lupron Depot is a prescription medication that is used to treat a variety of hormone-sensitive conditions. For advanced prostate cancer, it lowers testosterone to slow cancer growth and ease symptoms. In endometriosis, it reduces pain and the growth of abnormal tissue by lowering estrogen, often used for a limited time or with “add-back” therapy to minimize bone loss and hot flashes. It can also help improve anemia before surgery for uterine fibroids by reducing bleeding. (source: product monograph in Canada)

Mechanism of Action:
Lupron Depot (leuprolide acetate) functions by causing a brief increase in hormones like testosterone or estrogen. However, with continuous use, it tricks the body into significantly reducing the production of these hormones. This long-term lowering of hormones is how Lupron Depot helps manage conditions like prostate cancer by slowing cancer growth, endometriosis and fibroids by reducing tissue growth and pain, and early puberty by delaying its progression. This effect is reversible once the medication is stopped.

It is crucial to take Lupron Depot exactly as your doctor prescribes and read the product labeling information. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below summarizes potential side effects, risks and interactions. Before taking Lupron Depot (leuprolide acetate), it is essential to discuss all potential side effects, risks, and interactions with your doctor or pharmacist.

Common side effects – These are some frequently reported side effects of Lupron Depot (leuprolide acetate), but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or if you experience any other concerning symptoms.
• Hot flashes
• Injection site reactions
• Headache
• Mood Changes
• Decreased libido
• Vaginal Dryness
• Breast tenderness or swelling
• Muscle or joint pain
• Nausea
• Weight gain
• Dizziness
• Fatigue and Insomnia
• Hair Loss

Serious side effects – Stop taking Lupron Depot and seek immediate medical attention if you experience any of the following:
• Skin Rash
• Allergic reactions: Severe allergic reactions, including anaphylaxis, are possible. Seek immediate medical attention if you experience hives, swelling, difficulty breathing or throat tightness.
• Depression: Lupron can worsen existing depression or lead to new-onset depression. Report any changes in mood or thought to your doctor immediately.
• Bone loss: Long-term use of Lupron depot can lead to bone loss, increasing the risk of osteoporosis. Regular bone density scans are recommended during long-term use.
• Heart problems: In rare cases, Lupron Depot can affect the electrical activity of the heart, potentially leading to serious heart problems.
• Seizures: Seizures have been reported in some patients taking Lupron Depot.
• Changes in Blood sugar levels
• Increased Cholesterol levels

Individual reactions can vary. It is crucial to discuss potential side effects and risks with your doctor for a complete and up-to-date list.

Contraindications:

The following information is not an exhaustive list of contraindications. It is crucial to discuss all of your medical conditions past and present, and all the medications you are taking with your doctor or pharmacist before taking Lupron Depot (leuprolide acetate).

Lupron Depot (leuprolide acetate) is CONTRAINDICATED in the following situations and should not be used if:
Hypersensitivity: If you have a known allergy or hypersensitivity to leuprolide acetate, any of the components in Lupron Depot formulation, or similar medications (GnRH agonists), you should not take Lupron Depot.

Undiagnosed Abnormal Vaginal Bleeding: Lupron Depot should not be used in women with undiagnosed abnormal bleeding, as it may mask or complicate the diagnosis of underlying conditions.

Tell your doctor about all your medical conditions, past and present, before starting Lupron Depot. This is crucial because certain conditions can affect whether Lupron Depot is right for you. These conditions may include but are not limited to:
• A history of severe or uncontrolled mental health disorders (depression, psychosis), which requires careful evaluation by your doctor.
• History of seizures
• Certain heart conditions
• Osteoporosis or risk factors for bone loss

Drug Interactions:

Before taking Lupron Depot, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, please consult the official Lupron Depot product monograph:
https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/LUPRON_DEPOT_PM_EN.pdf
• Drugs that prolong QT interval: Lupron Depot can prolong the QT interval, a measure of the heart’s electrical activity. Taking Lupron with other drugs that also prolong the QT interval can increase the risk of serious heart rhythm problems, such as torsades de pointes. Examples of such drugs include antiarrhythmics, antipsychotics, and antibiotics.
• Drugs affecting pituitary function: Since Lupron Depot works by affecting the pituitary gland, which regulates hormone production, it can interact with other drugs that also affect pituitary function. This can lead to unpredictable hormonal effects.
• Antidiabetic medications: Lupron Depot can affect blood sugar levels, potentially interfering with the effectiveness of antidiabetic medications. People with diabetes should closely monitor their blood sugar levels while taking Lupron Depot and adjust their diabetes medication as needed under the guidance of their doctor.
• Anticoagulants (blood thinners): Lupron Depot may increase the risk of bleeding when taken with anticoagulants such as warfarin. Close monitoring of blood clotting factors may be necessary.

Pregnancy and Breastfeeding:

Lupron Depot is contraindicated during pregnancy and breastfeeding. It’s crucial to discuss your medical history and all medications you take with your doctor or pharmacist before starting Lupron Depot, as there are important contraindications.

Frequently Asked Questions about Lupron Depot at Canada Pharmacy Online:

What is Lupron Depot used for in dogs?

Lupron is a depot injection which contains, leuprolide, a hormone that inhibits the release of certain reproductive hormones. Lupron depot pet is mainly used in male dogs as a temporary chemical castration or as a treatment for advanced prostate cancer. This is reviewed by Dr Pippa Elliott, BVMS MRCVS.

Why is Lupron Depot more affordable from Canada than the United States?

Prescription drug prices, including Lupron Depot, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high-quality products.

How to use Lupron Depot?

It is given as an injection into a muscle (intramuscularly), once every month or once every 3 to 6 months. It should be given by a health care professional or taken as directed by your doctor.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Lupron Depot tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Lupron Depot at one time, as per your doctor's prescription.

Can I buy Lupron Depot over the counter from you?

No, Lupron Depot requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Can Lupron Depot be used on animals?

It can be used primarily on captive animals to suppress testosterone and sperm production.

Blog Posts:

Lupron Depot: Treating Adrenal Disease in Ferrets

Latest News

Assessment of a Polygenic Risk Score in Screening for Prostate Cancer (article published on April 9, 2025)

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This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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