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Merrem (Meropenem)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no brand product of Merrem.

Generic Equivalent of Merrem
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Meropenem 10 Vials of Powder for Solution
Manufacturer: Generic
Country: Canada
Dosage: 500 mg/1 vial
Qty-Price (USD):
Type: drug type
Product: Meropenem 10 Vials of Powder for Solution
Manufacturer: Generic
Country: Canada
Dosage: 1000 mg/1 vial
Qty-Price (USD):

Merrem Information

Meropenem at CanadaPharmacyOnline.com

The manufacturer of Merrem is Pfizer Canada ULC. Originally developed by AstraZeneca, the brand is a prominent carbapenem antibiotic used in hospital settings across Canada and globally. The brand Merrem is currently unavailable (at this pharmacy).

Generic meropenem is produced by several pharmaceutical companies that meet Health Canada's strict regulatory standards for safety and quality. Common generic manufacturers include Sandoz Canada, Teva Canada, and Apotex. The specific manufacturer of the dispensed medication may vary based on current pharmacy stock and regional distribution.

Important Information about Generic Meropenem

Generic meropenem contains the same active ingredient as brand-name Merrem. It must meet the same effectiveness and quality standards. This means it is designed to work like Merrem. Studies have shown that generic meropenem is bioequivalent to brand-name Merrem, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Merrem (meropenem) is an injectable antibiotic available in the following strengths:
• Powder for reconstitution: 500 mg/vial and 1000 mg/vial

Your doctor will determine the dosage and frequency based on the type and severity of the infection, as well as the patient's age and kidney function. It is typically administered every 8 hours via intravenous (I.V.) infusion.

Usage:

Merrem is a potent, broad-spectrum antibiotic reserved for serious or complicated bacterial infections. It is primarily used to treat complicated intra-abdominal infections, severe skin and soft tissue infections, and bacterial meningitis in both adults and children. Additionally, it is a critical treatment for complicated urinary tract infections and healthcare-associated pneumonia. Because it belongs to the carbapenem class, it is often used when other antibiotics have failed or when "superbugs" (multidrug-resistant bacteria) are suspected. It is effective only against bacterial infections and does not affect viral illnesses such as the flu or the common cold.

Mechanism of Action
Meropenem works by disrupting the synthesis of the bacterial cell wall, which is essential for bacterial survival. It penetrates the bacterial cell and binds to specific penicillin-binding proteins (PBPs). These proteins are responsible for building the peptidoglycan layer. That is, the structural "skeleton" of the cell wall. By blocking these proteins, meropenem prevents bacteria from completing their cell wall synthesis, leading to cell wall collapse and eventual rupture (lysis). Meropenem is particularly effective because it is highly resistant to many of the enzymes (beta-lactamases) that bacteria produce to destroy other antibiotics like penicillins and cephalosporins. This allows it to remain powerful even against highly resistant bacterial strains.

A doctor or nurse administers Merrem in a clinical or hospital setting. If you are receiving this medication as part of home-infusion therapy, follow all instructions provided in the product monograph.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Merrem, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Merrem (meropenem). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Merrem; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Diarrhea
• Headache
• Inflammation or pain at the injection site
• Nausea or vomiting
• Skin rash or itching

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Severe allergic reaction involving hives, swelling of the face or throat, and difficulty breathing.
• C. diff-associated Diarrhea: Severe, watery, or bloody diarrhea with stomach cramps and fever.
• Seizures: Especially in patients with existing central nervous system disorders or kidney issues.
• Severe Skin Reactions: Blistering or peeling skin (e.g., Stevens-Johnson Syndrome).

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Merrem, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not receive Merrem/meropenem if:
• Allergies: You have a known hypersensitivity to meropenem or other carbapenems.
• Severe Penicillin or Cephalosporin Allergy: Use with extreme caution if you have had an anaphylactic reaction to penicillins, as cross-reactivity can occur.

Tell your doctor about all of your medical conditions, past and present, before starting Merrem. This is crucial as certain conditions affect the drug's safety.
• Central Nervous System Disorders: Tell your doctor if you have a history of seizures or brain lesions, as the risk of seizures may increase.
• Kidney Disease: The dosage must be adjusted based on your kidney function to avoid toxic buildup.

Drug Interactions:

Before taking Merrem, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the highlights of prescribing information at https://labeling.pfizer.com/ShowLabeling.aspx?id=9318.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Merrem. Meropenem may interact with other medicines, including but not limited to:
• Oral Anticoagulants: Like many antibiotics, meropenem may increase the blood-thinning effects of warfarin.
• Probenecid: This can slow the elimination of meropenem from your body, leading to higher meropenem levels in your bloodstream.
• Valproic Acid/Sodium Valproate: Meropenem can significantly lower the levels of this seizure medication in your blood, increasing the risk of breakthrough seizures.

Pregnancy and Breastfeeding:

Merrem should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Small amounts of meropenem pass into human milk. Monitor your nursing infant for diarrhea or thrush. Inform your doctor if you are breastfeeding, planning to become pregnant, or breastfeeding.

Use in Children:

Merrem is approved for use in pediatric patients (aged 3 months and older). For children, the medical team carefully calculates the dose based on the child's weight and the specific infection being treated.

Frequently Asked Questions about Merrem at Canada Pharmacy Online

Why is Merrem more affordable in Canada than in the United States?

Prescription drug prices, including Merrem, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Merrem I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Merrem per prescription from your doctor.

Can I buy Merrem from you over the counter?

No, Merrem requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Merrem?

Yes, there is a generic alternative to Merrem: meropenem.

Blog Post:

Top 10 Things You Can Do to Improve Your Microbiome

Latest News:

WHO warns of widespread resistance to common antibiotics worldwide (article published on October 13, 2025)

Similar Drugs in the category of Anti-Infective/Antibiotic Medications:

   Xifaxan    Amoxil    Zithromax    Oracea    Augmentin

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
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