Ozempic (Semaglutide Injection)

Name: Ozempic
Brand: Novo Nordisk
SKU: 7625
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Ozempic (Local Pickup Only)

Manufacturer: Novo Nordisk

Country: Canada

Dosage: 2mg Multi-Use Pre-Filled Pen

Qty-Price (USD):

Type:

Product: Ozempic (Local Pickup Only)

Manufacturer: Novo Nordisk

Country: Canada

Dosage: 4mg Multi-Use Pre-Filled Pen

Qty-Price (USD):

Generic Equivalent of Ozempic

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Semaglutide Injection (Available by Late 2026)

Manufacturer: Generic

Country: Canada

Dosage: 2mg Multi-Use Pre-Filled Pen

Qty-Price (USD):

Type:

Product: Semaglutide Injection (Available by Late 2026)

Manufacturer: Generic

Country: Canada

Dosage: 4mg Multi-Use Pre-Filled Pen

Qty-Price (USD):

Ozempic Information

medically reviewed by Carol Hou (BSc. Pharm) on August 1, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Ozempic and Semaglutide Injection at CanadaPharmacyOnline.com

The brand-name Ozempic (semaglutide injection), manufactured by Novo Nordisk, is available in many countries worldwide, including Canada.

The generic version is currently unavailable.

Dosage:

The brand Ozempic is available in multi-use pre-filled pens designed to deliver weekly doses of 0.25 mg, 0.5 mg, 1 mg, and 2 mg.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Ozempic (semaglutide injection) is primarily used is to lower blood sugar and A1C in adults with type 2 diabetes when used in conjunction with diet and exercise. It is also approved to reduce the risk of major cardiovascular events like heart attack, stroke, or death in adults with type 2 diabetes and existing cardiovascular disease. Furthermore, based on the positive results of the FLOW trial, Ozempic has demonstrated a significant reduction in the risk of kidney disease progression, kidney failure, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease. Ozempic (semaglutide at doses up to 2 mg weekly) is not approved in Canada specifically for chronic weight management. However, semaglutide at a higher dose (up to 2.4 mg weekly) is approved in Canada for chronic weight management under the brand name Wegovy for individuals with obesity or overweight with at least one weight-related comorbidity.

Mechanism of Action:
Ozempic (semaglutide) is a GLP-1 receptor agonist that mimics the body's natural GLP-1 hormone to regulate blood sugar and appetite. It works by stimulating glucose-dependent insulin secretion from the pancreas, lowering glucagon secretion from the liver, and slowing gastric emptying to prevent post-meal blood sugar spikes. Additionally, Ozempic acts on brain receptors to reduce appetite and promote satiety, contributing to weight loss.

Take Ozempic exactly as your doctor prescribes, following the instructions in the Ozempic product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Ozempic, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with Ozempic (semaglutide injection). It is not an exhaustive list, and individual reactions can vary.

Common side effects - These are some common side effects of Ozempic, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Dizziness
• Fatigue
• Gastrointestinal issues (abdominal pain, bloating, burping, constipation, diarrhea, gas, heartburn, loss of appetite, nausea (very common), upset stomach, and vomiting)
• Headache
• Low blood sugar (hypoglycemia), especially in people with type 2 diabetes who are also taking insulin or sulfonylureas.
• Runny nose or sore throat

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Changes in vision (diabetic retinopathy complications): Especially in people with pre-existing diabetic eye disease, rapid improvement in blood sugar control can temporarily worsen retinopathy.
• Gallbladder problems (e.g., gallstones, cholecystitis): Symptoms can include sudden, severe abdominal pain, nausea, vomiting, fever, chills, light-colored stools, and yellowing of the skin or eyes (jaundice).
• Gastroparesis-like symptoms or slowed gastrointestinal motility: Ozempic significantly slows gastric emptying, which can lead to symptoms such as bloating, stomach cramps, nausea, and vomiting. In some rare instances, there have been reports of severe, persistent gastroparesis or intestinal blockage, though a definitive causal link to long-term gastroparesis directly caused by Ozempic is still under investigation, especially considering that diabetes itself is a risk factor for gastroparesis.
• Hypoglycemia (very low blood sugar): If taking Ozempic with other medications that lower blood sugar (like insulin or sulfonylureas), the risk of severe hypoglycemia is higher. Symptoms include dizziness, weakness, confusion, irritability, anxiety, excessive sweating, trembling, rapid heartbeat, and hunger.
• Kidney problems (acute kidney injury): Severe vomiting and diarrhea can lead to dehydration, which can worsen kidney function, particularly in those with existing kidney issues.
• Pancreatitis (inflammation of the pancreas): Symptoms include severe, persistent stomach pain that may spread to your back, with or without vomiting.
• Pulmonary aspiration: Due to Ozempic's effect of slowing gastric emptying, there is a theoretical or potential increased risk of pulmonary aspiration (food or liquid entering the lungs) during surgery or procedures requiring anesthesia or deep sedation. Healthcare providers may advise specific precautions, such as temporarily withholding Ozempic prior to elective procedures, to mitigate this potential risk.
• Severe allergic reactions: Symptoms can include hives, itching, rash, swelling of your face, lips, tongue, or throat, difficulty breathing or swallowing, dizziness, or a very rapid heartbeat.
• Thyroid tumors, including cancer: Ozempic carries a boxed warning from the FDA due to studies in rodents showing an increased risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC). It's unknown if this risk applies to humans. You should not use Ozempic if you or a family member has a history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Ozempic, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Ozempic should not be used if you:
• Are allergic to semaglutide or any of its ingredients.
• Are breastfeeding: It's not known if Ozempic passes into breast milk.
• Are pregnant or planning to become pregnant: It's not known if Ozempic will harm an unborn baby. It's recommended to discontinue Ozempic at least two months before a planned pregnancy.
• Have multiple endocrine neoplasia syndrome type 2 (MEN 2): This is a rare genetic condition that increases the risk of developing MTC. • Have a personal or family history of medullary thyroid carcinoma (MTC): Ozempic has a boxed warning due to the risk of thyroid C-cell tumors, including MTC, observed in rodent studies.
• Have Type 1 diabetes: Ozempic is not indicated for use in people with type 1 diabetes or for the treatment of diabetic ketoacidosis.

Tell your doctor about all of your medical conditions, past and present, before starting Ozempic. This is crucial because certain conditions can affect whether Ozempic is right for you. These conditions may include, but are not limited to:
• Concomitant use with insulin or sulfonylureas: Using Ozempic with these medications can increase the risk of low blood sugar (hypoglycemia). Doses of insulin or sulfonylureas may need to be adjusted.
• Diabetic retinopathy: Some patients with a history of diabetic retinopathy may experience a temporary worsening of vision when starting Ozempic.
• Gallbladder problems (cholelithiasis or cholecystitis): Acute events of gallbladder disease have been reported with GLP-1 receptor agonists.
• History of pancreatitis: While not an absolute contraindication, Ozempic has not been studied in patients with a history of pancreatitis, and acute pancreatitis has been reported with GLP-1 receptor agonists.
• History of suicidal ideation or attempts: While the association between GLP-1 receptor agonists and suicidal ideation or behavior is still under ongoing evaluation by regulatory bodies and a definitive causal link has not been fully established for Ozempic for its approved indications, caution is advised in patients with a history of suicidal ideation or attempts. Patients should be monitored for any changes in mood, behavior, thoughts, or feelings of depression and promptly report such symptoms to their doctor, especially since some weight management medications in other classes have been associated with these reports.
• Severe gastroparesis (stomach paralysis): Because Ozempic slows gastric emptying, it's generally not recommended for individuals with severe gastroparesis.
• Severe kidney problems/end-stage renal disease: Ozempic can cause acute kidney injury, especially if you experience severe gastrointestinal side effects like nausea, vomiting, or diarrhea leading to dehydration.

Drug Interactions:

Before taking Ozempic, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Ozempic product monograph: https://www.novonordisk.ca/content/dam/nncorp/ca/en/products/ozempic-product-monograph.pdf

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also important to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Ozempic. Ozempic may interact with other medicines but is not limited to:

Medications that lower blood sugar (Increased risk of hypoglycemia):
• Glinides: (e.g., repaglinide, nateglinide) Similar to sulfonylureas, glinides also promote insulin release and can increase the risk of hypoglycemia when combined with Ozempic.
• Insulin: Both Ozempic and insulin lower blood sugar. Combining them significantly increases the risk of hypoglycemia (low blood sugar), which can be severe. Your doctor will likely adjust your insulin dose when starting Ozempic.
• Other diabetes medications: Any medication that lowers blood glucose can increase the risk of hypoglycemia when combined with Ozempic. While some other medications (e.g., certain antimalarials like chloroquine/hydroxychloroquine and some antibiotics like clarithromycin) can affect blood glucose levels, their interaction with Ozempic for an increased risk of hypoglycemia is generally less direct or significant than with insulin or sulfonylureas. Blood sugar monitoring is always important when combining diabetes medications or drugs that can impact glucose.
• Sulfonylureas: (e.g., glipizide, glimepiride, glyburide) These oral diabetes medications stimulate insulin production. Like insulin, using them with Ozempic can lead to dangerously low blood sugar. While some other medications (e.g., certain antimalarials like chloroquine/hydroxychloroquine and some antibiotics like clarithromycin) can affect blood glucose levels, their interaction with Ozempic for an increased risk of hypoglycemia is generally less direct or significant than with insulin or sulfonylureas. Blood sugar monitoring is always important when combining diabetes medications or drugs that can impact glucose.

Oral Medications (Decreased effectiveness of oral medications):
Ozempic slows down gastric emptying (how quickly food leaves your stomach). This can affect the absorption of oral medications, potentially making them less effective. This is particularly important for medications where precise absorption is crucial, such as:
• Birth control pills: While Ozempic slows gastric emptying, clinical studies have not shown a significant impact on the absorption or effectiveness of oral contraceptives. However, if you experience severe gastrointestinal symptoms such as vomiting or diarrhea, this could potentially affect the absorption of any oral medication, including birth control. Discuss your contraception with your doctor if you have concerns or experience such symptoms.
• Digoxin (Lanoxin): A heart failure medication.
• Levothyroxine (Synthroid): Thyroid hormone replacement. Due to slowed gastric emptying, Ozempic may alter the absorption of levothyroxine, potentially requiring dose adjustments and careful monitoring of thyroid hormone levels.
• Phenytoin (Dilantin): An antiseizure medication.
• Warfarin (Jantoven): A blood thinner.

Other potential interactions:
• Antidepressants: Some antidepressants, particularly SSRIs and SNRIs, can also cause gastrointestinal side effects such as nausea or diarrhea. Co-administration with Ozempic may intensify these symptoms. While some antidepressants can affect blood sugar levels, there is no strong evidence to suggest they directly impact Ozempic's primary effectiveness in a clinically significant way beyond potential additive side effects.
• Certain blood pressure medications (beta-blockers): (e.g., atenolol, propranolol, metoprolol) Beta-blockers can mask the symptoms of low blood sugar (like tremors and rapid heart rate), making it harder to recognize hypoglycemia if it occurs.
• Other diabetes medications: Concomitant use of Ozempic with other glucose-lowering medications, particularly those that directly stimulate insulin secretion or provide exogenous insulin (e.g., insulin, sulfonylureas, glinides), significantly increases the risk of hypoglycemia, necessitating dose adjustments and careful monitoring. While certain other medications (e.g., specific antimalarials or antibiotics) may indirectly affect blood glucose levels, their interaction with Ozempic for an increased risk of hypoglycemia is generally less direct compared to insulin or insulin secretagogues. Nonetheless, close blood sugar monitoring is always recommended when combining Ozempic with any medication that can impact glucose metabolism.

Alcohol
While there's no direct interaction, alcohol can significantly affect blood sugar levels, either raising or lowering them, which can interfere with Ozempic's effectiveness and increase the risk of hypoglycemia.

Herbal Supplements
Several herbal supplements are known to lower blood sugar and can increase the risk of hypoglycemia when taken with Ozempic. These include aloe vera, banaba, berberine, bitter melon, chromium, gymnema, prickly pear cactus, white mulberry.

Frequently Asked Questions about Ozempic at Canada Pharmacy Online:

Why is Ozempic more affordable in Canada than in the United States?

Prescription drug prices, including Ozempic, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many pens I am allowed to order at one time?

CanadaP.harmacyOnline.com can only dispense a maximum of a three-month supply of Ozempic at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Ozempic requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

How is Ozempic administered?

Ozempic is injected under the skin (subcutaneously) once a week on the same day each week, at any time of the day, with or without meals. Common injection sites are the stomach (abdomen), thigh, or upper arm. It's important to rotate injection sites.

What if I miss a dose of Ozempic?

If you miss a dose, take it as soon as possible, within 5 days of the missed dose. If more than 5 days have passed since the missed dose, skip it and take the next dose on your regularly scheduled day. For extended periods of missed doses (e.g., more than two consecutive weeks), it is advisable to consult your doctor before restarting.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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