Prestalia (Perindopril Arginine/Amlodipine Besvlate)

Name: Prestalia
Brand: Servier
SKU: 7045
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Prestalia

Manufacturer: Servier

Country: Canada

Dosage: 3.5 mg/2.5 mg

Qty-Price (USD):

Type:

Product: Prestalia

Manufacturer: Servier

Country: Canada

Dosage: 7 mg/5 mg

Qty-Price (USD):

Type:

Product: Prestalia

Manufacturer: Servier

Country: Canada

Dosage: 14 mg/10 mg

Qty-Price (USD):

Generic Equivalent of Prestalia

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Perindopril Arginine/Amlodipine Besvlate

Manufacturer: Generic

Country: Canada

Dosage: 3.5 mg/2.5 mg

Qty-Price (USD):

Type:

Product: Perindopril Arginine/Amlodipine Besvlate

Manufacturer: Generic

Country: Canada

Dosage: 7 mg/5 mg

Qty-Price (USD):

Type:

Product: Perindopril Arginine/Amlodipine Besvlate

Manufacturer: Generic

Country: Canada

Dosage: 14 mg/10 mg

Qty-Price (USD):

Prestalia Information

Prestalia at CanadaPharmacyOnline.com

The manufacturer of the brand-name Prestalia is Servier Canada Inc. Prestalia is marketed in Canada as Viacoram. Brand-name Prestalia is available at this pharmacy in all three strengths.

Generic perindopril arginine/amlodipine besylate is also available at this pharmacy in all three strengths, manufactured in Canada by various manufacturers that meet Health Canada’s strict quality and safety standards. The specific manufacturer of your dispensed medication may vary based on pharmacy inventory.

Important Information about Generic Perindopril Arginine/Amlodipine Besylate

Generic perindopril arginine/amlodipine besylate contains the same active ingredients as brand-name Prestalia. It must meet the same effectiveness and quality standards. This means it is designed to work like Prestalia. Studies have shown that the generic is bioequivalent to brand-name Prestalia, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Prestalia (perindopril arginine/amlodipine besylate) is available in the following oral strengths:
• Tablets: 3.5 mg/2.5 mg, 7 mg/5 mg, and 14 mg/10 mg.

The dose is one tablet taken once daily, with or without food, at the same time each day. Treatment is typically started at the lowest strength (3.5 mg/2.5 mg). If blood pressure remains uncontrolled after 4 weeks, the dose may be increased to 7 mg/5 mg and then, if needed, to the maximum dose of 14 mg/10 mg after a further 4 weeks. The dosage should be adjusted according to your doctor’s instructions. Do not switch between perindopril products without guidance from your doctor.

Usage:

Prestalia is a combination blood pressure medication indicated for the treatment of mild to moderate essential hypertension in adults between the ages of 18 and 65 for whom combination therapy is appropriate. Because clinical experience is limited in older populations, this medication is contraindicated for starting treatment in patients over 65 years of age. It contains two active ingredients: perindopril arginine, an ACE inhibitor, and amlodipine besylate, a calcium channel blocker. Unlike most combination blood pressure medications, the lowest strength (3.5 mg/2.5 mg) is approved for use as a first-line treatment for patients newly diagnosed with mild to moderate hypertension.

High blood pressure often causes no symptoms but can lead to serious complications such as a heart attack, stroke, and kidney disease if left untreated. Take Prestalia daily as directed by your doctor, even when you feel well.

Mechanism of Action
Perindopril works by blocking an enzyme (ACE) that the body uses to produce angiotensin II, a substance that causes blood vessels to tighten. By blocking this enzyme, perindopril helps blood vessels relax and lowers blood pressure. Amlodipine works by relaxing the smooth muscle in the walls of blood vessels, allowing blood to flow more easily. Together, these two actions lower blood pressure more effectively than either drug alone. A further benefit is that amlodipine-associated ankle swelling is reduced when it is combined with an ACE inhibitor such as perindopril.

Take Prestalia exactly as your doctor prescribes, as directed in the product monograph. Be sure to drink enough water and stay hydrated, especially during hot weather, exercise, or after vomiting or diarrhea, as dehydration can cause your blood pressure to drop too low.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Prestalia, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Prestalia (perindopril arginine/amlodipine besylate). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Prestalia; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Dizziness
• Dry, persistent cough
• Edema
• Fatigue
• Flushing
• Headache
• Nausea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• High Potassium (Hyperkalemia): Muscle weakness or an abnormal heartbeat.
• Hypotension: Severe dizziness or fainting.
• Liver Problems: Yellowing of the skin or eyes, dark urine, or severe stomach pain.
• Severe Allergic Reaction: Swelling of the face, lips, tongue, or throat, or sudden difficulty breathing or swallowing. This is a medical emergency, and Prestalia should be stopped immediately.
• Worsening Chest Pain or Heart Attack
• Worsening Kidney Function: Decreased urine output or rapid weight gain with swelling. Seek immediate medical attention.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Prestalia, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Prestalia/perindopril arginine/amlodipine besylate if:
• Allergies: You have a known hypersensitivity to perindopril, amlodipine, any other ACE inhibitor, or any of the ingredients in the tablet.
• Congestive Heart Failure: Patients with heart failure were excluded from clinical trials; Prestalia is contraindicated for this condition.
• Diabetes with Aliskiren: ACE inhibitors must not be combined with aliskiren in patients with diabetes.
• History of Angioedema: You have a history of swelling of the face or throat related to previous ACE inhibitor treatment, or hereditary or unexplained angioedema.
• Lactose Intolerance: Do not take this medication if you have rare hereditary conditions such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption, as the tablets contain lactose.
• Moderate to Severe Renal Impairment: Prestalia is strictly contraindicated if your kidney function is impaired, specifically if your creatinine clearance is less than 60 mL/min.
• Sacubitril/Valsartan (Entresto): Do not take Prestalia within 36 hours of switching to or from sacubitril/valsartan.
• Severe Aortic Stenosis or Mitral Valve Stenosis (narrowing of the heart valves).

Tell your doctor about all of your medical conditions, past and present, before starting Prestalia. This is crucial as certain conditions affect the drug’s safety.
• A recent heart attack
• Diabetes
• High potassium levels
• Kidney disease (Prestalia is not recommended for any degree of kidney disease and is strictly banned if your kidney function drops below a certain level)
• Liver disease
• Low-salt diet

Drug Interactions:

Before taking Prestalia, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please refer to the product monograph at https://pdf.hres.ca/dpd_pm/00075585.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Prestalia. Prestalia may interact with other medicines, including but not limited to:
• Aliskiren: Increases the risk of low blood pressure, high potassium, and kidney failure.
• Diuretics (water pills): May result in an excessive drop in blood pressure, especially after the first dose.
• Grapefruit and grapefruit juice can significantly increase the amlodipine levels in your blood; avoid consuming them while taking this medication.
• Lithium: Perindopril can raise lithium levels in the blood to potentially harmful levels.
• NSAIDs (e.g., ibuprofen, naproxen): May reduce the blood pressure-lowering effect of Prestalia and can worsen kidney function.
• Other antihypertensive drugs: Additive blood pressure-lowering effects. Dose adjustments may be required.
• Potassium supplements or potassium-sparing diuretics (e.g., spironolactone)
• Salt substitutes containing potassium can raise potassium levels.

Pregnancy and Breastfeeding:

Prestalia can cause serious harm or death to an unborn baby, especially if you take it during the second or third trimester of pregnancy. Stop taking Prestalia as soon as you know you are pregnant and contact your doctor immediately. Women of childbearing potential should use effective contraception while taking Prestalia. If you are planning to become pregnant, speak to your doctor before continuing treatment. It is unknown if perindopril passes into human breast milk. Discuss the risks and benefits with your doctor.

Use in Children:

The safety and efficacy of Prestalia in children under 18 years of age have not been established.

Frequently Asked Questions about Prestalia at Canada Pharmacy Online

Why is Prestalia more affordable in Canada than in the United States?

Prescription drug prices, including Prestalia, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Prestalia I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of Prestalia per your doctor's prescription.

Can I buy Prestalia from you over the counter?

No, Prestalia requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Prestalia?

Yes, generic perindopril arginine/amlodipine besylate is available at this pharmacy.

Blog Post:

Natural Ways to Lower Your Blood Pressure

Latest News:

Effectiveness of an amlodipine and perindopril arginine-based strategy for hypertension management – Pan African Medical Journal (published December 2025)

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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