Rifadin (Rifampin)

Name: Rifadin
Brand: Generic
SKU: 1985
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no brand product of Rifadin.

Generic Equivalent of Rifadin

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Rifampin

Manufacturer: Generic

Country: Canada

Dosage: 150 mg

Qty-Price (USD):

Type:

Product: Rifampin

Manufacturer: Generic

Country: India

Dosage: 300 mg

Qty-Price (USD):

Rifadin Information

Rifampin at CanadaPharmacyOnline.com

The manufacturer of the brand-name Rifadin (rifampin) is Sanofi-Aventis Canada Inc. While Rifadin has a long history as a primary treatment for tuberculosis, its availability in Canada has changed over time. The brand Rifadin is currently unavailable (at this pharmacy).

Generic rifampin (also known as rifampicin) is currently produced by several manufacturers that meet Health Canada's strict quality and safety standards. Common generic versions available in Canada include Rofact, manufactured by Bausch Health (formerly Valeant), and other global generics such as R-CIN. The specific manufacturer of your dispensed medication may vary based on pharmacy inventory.

Important Information about Generic Rifampin

Generic rifampin contains the same active ingredient as brand-name Rifadin. It must meet the same effectiveness and quality standards. This means it is designed to work like Rifadin. Studies have shown that generic rifampin is bioequivalent to brand-name Rifadin, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Rifampin is available in the following oral strengths and forms:
• Capsules: 150 mg and 300 mg.

The standard adult dose for the treatment of tuberculosis is typically 600 mg taken once daily. For the prevention of meningococcal meningitis, the dose is often 600 mg taken twice daily for 2 days. Your doctor will determine the exact dose based on your body weight and the specific condition being treated.

Usage:

Rifadin is a powerful antibiotic primarily used as a first-line treatment for all forms of tuberculosis (TB), usually in combination with other medications like isoniazid and ethambutol. It is also used to eliminate meningitis-causing bacteria from the nose and throat of asymptomatic carriers to prevent the spread of the disease to others. Beyond these primary uses, your doctor may prescribe rifampin for leprosy, Legionnaires' disease, and certain serious staphylococcal infections. Because it is an antibiotic, it is only effective against bacterial infections; it will not work for viral illnesses such as the common cold or flu. It is essential to complete the full course of therapy, which can last several months, even if you feel better after a few weeks, to ensure the bacteria are fully eradicated and to prevent antibiotic resistance.

Mechanism of Action
Rifampin, the active agent in Rifadin, works by directly inhibiting the bacteria's ability to synthesize proteins necessary for survival. It works by binding to the beta-subunit of DNA-dependent RNA polymerase, a vital enzyme that bacteria use to transcribe their DNA into RNA. By blocking this enzyme, rifampin physically obstructs the path of the growing RNA chain at an early stage. This prevents the bacteria from replicating their genetic code and halts all downstream protein synthesis, leading to the rapid death of the bacterial cell. Because rifampin specifically targets bacterial RNA polymerase and does not inhibit the equivalent mammalian enzyme, it is highly effective at killing bacteria while remaining selectively toxic to human cells and generally safe.

Take Rifadin exactly as your doctor prescribes, following the instructions in the product monograph. For best absorption, it should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal, with a full glass of water.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Rifadin, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Rifadin (rifampin). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Rifadin; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Flushing or itching.
• Headache or dizziness.
• Heartburn or loss of appetite.
• Nausea, vomiting, or stomach cramps.
• Orange-red discoloration of urine, sweat, saliva, tears, and stools (this is expected and harmless).

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Severe allergic reaction involving swelling of the face, tongue, or throat, and difficulty breathing.
• Easy Bleeding/Bruising: This may indicate a vitamin K deficiency or blood-clotting issue.
• Flu-like Symptoms: Fever, chills, and bone pain may occur if you take the medication on an irregular schedule.
• Liver Problems: Yellowing of the eyes or skin (jaundice), dark urine, or severe upper stomach pain.
• Severe Skin Reactions: Widespread red rash, blistering, or peeling of the skin.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Rifadin, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Rifadin/rifampin if:
• Allergies: You have a known hypersensitivity to rifampin or any other rifamycin (such as rifabutin or rifapentine).
• Drug Interactions: You are taking certain antiviral medications (e.g., atazanavir and ritonavir) that may be dangerous when combined with other medications.

Tell your doctor about all of your medical conditions, past and present, before starting Rifadin. This is crucial as certain conditions affect the drug's safety.
• Adrenal Gland Problems: This medication can affect how your body processes steroid hormones.
• Diabetes: Rifampin can affect blood sugar levels and may require monitoring.
• Liver Disease: A history of hepatitis or chronic liver issues requires close monitoring.
• Porphyria: A rare enzyme problem that may be worsened by rifampin.

Drug Interactions:

Before taking Rifadin, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please visit the manufacturer’s site at https://products.sanofi.us/rifadin/rifadin.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Rifadin. Rifadin may interact with other medicines, including but not limited to:
• Antifungals and Antivirals: Levels of these drugs (e.g., ketoconazole, HIV meds) can be greatly reduced.
• Blood Thinners: It can decrease the effect of warfarin, requiring frequent monitoring of your clotting time (INR).
• Diabetes Meds: It may lower the effectiveness of oral diabetes medications.
• Hormonal Contraceptives: Rifampin significantly decreases the effectiveness of birth control pills. You should use a non-hormonal (barrier) method of birth control during treatment.

Pregnancy and Breastfeeding:

Rifadin is generally considered safe for treating active tuberculosis during pregnancy, as the risks of untreated TB are far greater. However, it may increase the risk of bleeding in the newborn if taken late in pregnancy; both mother and baby may need vitamin K supplements. Rifampin passes into breast milk in small amounts but is generally considered compatible with breastfeeding. The breast milk may also turn a harmless orange-red color.

Use in Children:

Rifadin is safe for use in children and infants. For children, the dose is carefully determined by the doctor based on the child's body weight. If a child cannot swallow capsules, a pharmacist can prepare a special liquid oral suspension.

Frequently Asked Questions about Rifadin at Canada Pharmacy Online

Why is Rifadin more affordable in Canada than in the United States?

Prescription drug prices, including Rifadin, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Rifadin I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Rifadin per prescription from your doctor.

Can I buy Rifadin from you over the counter?

No, Rifadin requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Rifadin?

Yes, there is a generic alternative to Rifadin: rifampin.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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