Suprane (Desflurane)

Name: Suprane
Brand: Baxter Healthcare
SKU: 7581
Availability: InStock

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Qty-Price (USD)

Type:

Product: Suprane

Manufacturer: Baxter Healthcare

Country: Canada

Dosage: 240 ml

Qty-Price (USD):

Generic Equivalent of Suprane

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There is no generic product of Suprane.

Suprane Information

Suprane at CanadaPharmacyOnline.com

The manufacturer of Suprane (desflurane) is consistent across most major markets, primarily handled by Baxter Healthcare. Unlike many oral medications, Suprane is a specialized volatile liquid used for inhalation anesthesia. It is typically supplied directly to hospitals and surgical centers. In the United States and Canada, Baxter Corporation remains the primary manufacturer and distributor of the brand-name version.

While the brand-name Suprane remains the industry standard, generic desflurane has become available in recent years. In Canada, Blue-Zone Technologies Ltd. received authorization for a generic version produced through a unique recovery and purification process. In the US, the FDA has approved generic versions from manufacturers such as Shanghai Hengrui Pharmaceutical Co. Generic desflurane is produced to meet the same stringent regulatory standards as Suprane. The specific manufacturer used by your medical facility may vary.

The generic desflurane is currently unavailable (at this pharmacy).

Dosage:

Suprane is available in a 240 ml bottle.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Suprane (desflurane) is a general anesthetic used to induce and maintain loss of consciousness during surgical procedures. In adults, it can be used for both induction (starting anesthesia) and maintenance. In children and infants, it is primarily used for the maintenance of anesthesia after sleep has been induced with other medications. It is favored in outpatient surgeries because its low blood solubility allows patients to wake up more quickly than with many other anesthetics.

Mechanism of Action
The exact mechanism of Suprane is not fully understood, but it belongs to the class of halogenated ethers. It acts primarily on the Central Nervous System (CNS) by modulating ion channels. In simple terms, it boosts the brain's natural "calming" signals and weakens the "stimulating" signals. This combination slows down brain activity enough to cause unconsciousness and prevent pain during surgery.

Suprane also relaxes blood vessels, widening them. This can lower blood pressure and, depending on the dose, may cause the heart to beat faster.

Suprane is administered by an anesthesiologist or certified anesthesia provider in a controlled surgical setting, following the instructions in the product monograph in Canada.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Suprane, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Suprane (desflurane). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Suprane; others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Fast heart rate
• Headache
• Nausea and vomiting are frequent occurrences upon waking from general anesthesia.
• Respiratory irritation, including coughing, increased secretions

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Laryngospasm: A sudden spasm of the vocal cords that makes breathing difficult.
• Liver injury: Signs include jaundice, dark urine, and unexplained fever after surgery.
• Malignant hyperthermia: A rare, life-threatening reaction causing a rapid rise in body temperature, severe muscle rigidity, and a fast heart rate.
• Perioperative hyperkalemia: Elevated potassium levels, which can lead to heart rhythm changes, particularly in patients with underlying neuromuscular diseases like Duchenne muscular dystrophy.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Suprane, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Suprane/desflurane if:
• Halogenated sensitivity: You have had a previous severe allergic reaction to desflurane, isoflurane, or sevoflurane.
• Liver dysfunction: You have a history of hepatitis or unexplained fever after previous anesthesia with halogenated agents.
• Malignant hyperthermia: You have a known or suspected genetic susceptibility to this condition.
• Pediatric induction: Suprane is strictly contraindicated as the sole agent for induction in children due to the high risk of severe airway spasms.

Tell your doctor about all of your medical conditions, past and present, before using Suprane. This is crucial as certain conditions affect the drug's safety.
• Asthma or COPD: Due to Suprane's potential to irritate the airways.
• Coronary Artery Disease: Suprane can cause rapid increases in heart rate that may stress the heart.
• Intracranial pressure: It may increase the intracranial pressure. Specific dosing adjustments are required.

Drug Interactions:

Before taking Suprane, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the highlights of prescribing information from Baxter at https://baxterpi.com/pi-pdf/Suprane.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Suprane. Suprane may interact with other medicines, including but not limited to:
• Desiccated CO2 absorbents: Suprane can react with dry carbon dioxide absorbents in the anesthesia machine, producing carbon monoxide.
• Neuromuscular blockers (muscle relaxants): Suprane significantly enhances the effects of drugs such as vecuronium or succinylcholine.
• Nitrous Oxide: Also reduces the required concentration of Suprane.
• Opioids and Benzodiazepines: These medications reduce the amount of Suprane needed.

Pregnancy and Breastfeeding:

Suprane is not recommended for use during labor or vaginal delivery as it is a uterine relaxant. Its safety in pregnant women has not been established, and it should only be used if the benefits clearly outweigh the potential risks to the fetus. It is unknown if desflurane is excreted in human milk. However, because of its rapid elimination from the body, breastfeeding can typically be resumed once the mother is fully awake and recovered. Inform your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

Use in Children:

In pediatric patients, Suprane is approved only for maintenance of anesthesia after intubation. It is not used to "mask" a child to sleep (induction) because it is highly irritating to the airway and can cause dangerous breath-holding or spasms of the vocal cords.

Frequently Asked Questions about Suprane at Canada Pharmacy Online

Why is Suprane more affordable in Canada than in the United States?

Prescription drug prices, including Suprane, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Can I buy Suprane over the counter from you?

No, Suprane requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Suprane?

No, the generic desflurane is currently unavailable.

Blog Post:

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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