Tenoretic (Atenolol/Chlorthalidone)

Name: Tenoretic
Brand: Generic
SKU: 2094
Availability: InStock

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Product

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There is no brand product of Tenoretic.

Generic Equivalent of Tenoretic

Type

Product

Manufacturer

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Type:

Product: Atenolol/Chlorthalidone

Manufacturer: Generic

Country: Canada

Dosage: 50 mg/25 mg

Qty-Price (USD):

Type:

Product: Atenolol/Chlorthalidone

Manufacturer: Generic

Country: Canada

Dosage: 100 mg/25 mg

Qty-Price (USD):

Tenoretic Information

Atenolol/Chlorthalidone at CanadaPharmacyOnline.com

The manufacturer of the brand-name Tenoretic was AstraZeneca Canada Inc. The brand Tenoretic is currently unavailable at this pharmacy.

The generic atenolol/chlorthalidone tablets are available in two strengths. They are manufactured in Canada by various manufacturers that meet Health Canada's quality and safety standards. The specific manufacturer of your dispensed medication may vary based on pharmacy inventory.

Important Information about Generic Atenolol/Chlorthalidone

Generic atenolol/chlorthalidone contains the same active ingredients as brand-name Tenoretic. It must meet the same effectiveness and quality standards. This means it is designed to work like Tenoretic. Studies have shown that generic atenolol/chlorthalidone is bioequivalent to brand-name Tenoretic, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information on generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Tenoretic (atenolol/chlorthalidone) is available in the following oral strengths:
• Tablets: 50 mg/25 mg and 100 mg/25 mg.

The dose is one tablet taken once daily. The usual starting dose is the 50 mg/25 mg tablet. If an adequate blood pressure response is not achieved, the dose may be increased to the 100 mg/25 mg tablet, also taken once daily. Dosage should be adjusted according to your doctor's instructions.

Usage:

Tenoretic is a combination blood pressure medication indicated for the treatment of hypertension. It contains two active ingredients that each lower blood pressure in a different way: atenolol, a cardioselective (heart-selective) beta-blocker, and chlorthalidone, a thiazide-like diuretic (water pill). Together, they lower blood pressure more effectively than either drug alone. Tenoretic is suitable for patients who require more than one medication to control their blood pressure. High blood pressure often has no symptoms but can lead to serious complications such as a heart attack, stroke, and kidney disease if left untreated. Take Tenoretic daily as directed by your doctor, even when you feel well. Do not stop taking Tenoretic without first consulting your doctor.

Mechanism of Action
Atenolol works by selectively blocking beta-1 receptors in the heart. This slows the heart rate and reduces the force of each heartbeat, lowering blood pressure and reducing the heart's workload. Unlike some other beta-blockers, atenolol is hydrophilic (water-soluble), which means it is less likely to cross the blood-brain barrier and is generally associated with fewer sleep disturbances and fewer central nervous system side effects. Chlorthalidone is a long-acting diuretic that works in the kidneys to remove extra salt and water from the body through urine. This reduces the volume of fluid in the blood vessels, thereby lowering blood pressure. Together, these two mechanisms provide additive blood pressure-lowering effects.

Take Tenoretic exactly as your doctor prescribes, as directed in the product monograph. Do not crush or chew the tablets.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Tenoretic, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Tenoretic (atenolol/chlorthalidone). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Tenoretic; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Cold hands and feet
• Diarrhea or nausea
• Dizziness, fatigue, or tiredness
• Increased urination (from the chlorthalidone component)
• Muscle cramps
• Slow heartbeat (bradycardia)

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Allergic Reaction: Hives, rash, or swelling of the face, lips, tongue, or throat.
• Bronchospasm (Breathing Difficulty): Sudden wheezing, shortness of breath, or chest tightness.
• Heart Problems: A very slow pulse, fainting, or significant worsening of heart failure symptoms such as sudden weight gain, severe swelling of the ankles, or difficulty breathing.
• Low Blood Pressure (Hypotension): Severe dizziness or fainting, especially when standing up quickly.
• Low Potassium (Hypokalemia): Muscle cramps, weakness, or an irregular heartbeat. Chlorthalidone can cause potassium loss; severe hypokalemia can cause dangerous heart rhythm problems.
• Masking of Low Blood Sugar (Hypoglycemia): Atenolol can hide the fast heartbeat that normally warns diabetic patients of low blood sugar. Sweating may still occur. Monitor blood sugar carefully.
• Worsening Kidney Function: Decreased urine output or rapid swelling. Seek medical attention promptly.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Tenoretic, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Tenoretic/atenolol/chlorthalidone if:
• Allergies: You have a known hypersensitivity to atenolol, chlorthalidone, sulphonamide-derived drugs, or any ingredient in the tablet.
• Asthma or Bronchospasm (History of): Atenolol is contraindicated in patients with bronchial asthma or a history of bronchospasm. Even small doses may trigger breathing problems.
• Heart Block or Slow Heart Rate: Second or third-degree atrioventricular (AV) block, sick sinus syndrome, or a resting heart rate that is consistently too slow.
• Heart Failure (Uncontrolled or Cardiogenic Shock).
• Severe Kidney Disease or Anuria

Tell your doctor about all of your medical conditions, past and present, before starting Tenoretic. This is crucial as certain conditions affect the drug's safety.
• Diabetes — atenolol can mask the symptoms of low blood sugar
• Gout or high uric acid levels — chlorthalidone can raise uric acid and trigger gout
• Kidney or liver disease
• Peripheral arterial disease — atenolol may worsen poor circulation in the limbs
• Thyroid disease — atenolol can mask signs of an overactive thyroid; never stop atenolol suddenly if you have thyroid disease
• If you are on a low-salt diet

Abrupt Withdrawal Warning:

Do not stop taking Tenoretic suddenly, especially if you have coronary artery disease. Abrupt discontinuation of beta-blockers can trigger severe chest pain (angina), a heart attack, or dangerous heart rhythm problems. If you need to stop Tenoretic, your doctor will gradually reduce the dose over at least 2 weeks under close supervision.

Drug Interactions:

Before taking Tenoretic, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please refer to the product monograph at https://pdf.hres.ca/dpd_pm/00035740.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Tenoretic. Tenoretic may interact with other medicines, including but not limited to:
• Antidiabetic agents (insulin and oral hypoglycemics): Atenolol can mask the warning signs of low blood sugar (especially rapid heartbeat). Monitor blood glucose carefully.
• Calcium channel blockers (especially verapamil and diltiazem): Combining these with atenolol can cause dangerously slow heart rates and AV block. Generally, avoid.
• Clonidine: If both medications need to be stopped, atenolol should be withdrawn several days before clonidine to avoid a dangerous rebound rise in blood pressure.
• Lithium: Chlorthalidone can raise lithium blood levels to harmful concentrations. Monitor lithium levels closely.
• NSAIDs (e.g., ibuprofen, naproxen): May reduce the blood pressure-lowering effect of Tenoretic.
• Other antihypertensive drugs: Additive blood pressure-lowering effects may require dose adjustments.

Pregnancy and Breastfeeding:

Tenoretic is not recommended during pregnancy. Atenolol can cause harm to an unborn baby, including low birth weight, a slow heart rate, and low blood sugar in the newborn. Chlorthalidone crosses the placental barrier and may cause jaundice and other problems in newborns. Stop taking Tenoretic as soon as you know you are pregnant and contact your doctor immediately.

Tenoretic is contraindicated during breastfeeding. Atenolol accumulates significantly in breast milk and may cause a slow heart rate and low blood sugar in nursing infants. Discuss alternative blood pressure medications with your doctor.

Use in Children:

The safety and efficacy of Tenoretic in patients under 18 years of age have not been established. It is not recommended for use in children.

Frequently Asked Questions about Tenoretic at Canada Pharmacy Online

Why is Tenoretic more affordable in Canada than in the United States?

Prescription drug prices, including Tenoretic, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Tenoretic I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of Tenoretic per your doctor's prescription.

Can I buy Tenoretic from you over the counter?

No, Tenoretic requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Tenoretic?

Yes, the generic atenolol/chlorthalidone tablets are available at this pharmacy.

Blog Post:

Hypertension: Don't Let the Silent Killer Lurk in Your Body

Latest News:

Comparative efficacy and safety of chlorthalidone vs hydrochlorothiazide in hypertension management: chlorthalidone showed greater reductions in both systolic and diastolic blood pressure and superior nocturnal control – World Journal of Cardiology (published February 2026)

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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