Monovisc (Sodium Hyaluronate)

Name: Monovisc
Brand: Anika
SKU: 6628
Availability: InStock

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Product

Manufacturer

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Dosage

Qty-Price (USD)

Type:

Product: Monovisc 4ml Injection

Manufacturer: Anika

Country: Canada

Dosage: 20 mg/ml

Qty-Price (USD):

Type:

Product: Monovisc 4ml Injection

Manufacturer: Anika

Country: Turkey

Dosage: 22 mg/ml

Qty-Price (USD):

Generic Equivalent of Monovisc

Type

Product

Manufacturer

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Qty-Price (USD)

There is no generic product of Monovisc.

Monovisc Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on June 6, 2025.

Monovisc at CanadaPharmacyOnline.com

Brand Monovisc (sodium hyaluronate), manufactured by Anika, is available in Canada and Turkey.

Generic sodium hyaluronate is currently not available (at this pharmacy).

Dosage:

Brand Monovisc is commonly available as a single-use injection containing 88 mg of sodium hyaluronate in 4 ml (22 mg/ml concentration), dissolved in physiologic saline.

Your doctor will determine the appropriate dose and treatment duration based on your needs and condition.

Usage:

Monovisc (sodium hyaluronate) is a prescription medicine used to relieve knee pain caused by osteoarthritis, a condition where the natural lubricating fluid in the joint (hyaluronic acid) may be diminished. This treatment involves a single injection directly into the knee joint, thereby reducing the pain. It’s typically recommended for individuals whose knee osteoarthritis pain hasn’t improved with other non-drug treatments or basic pain relievers.

For more information, please refer to the product labeling information: https://www.accessdata.fda.gov/cdrh_docs/pdf9/P090031b.pdf

Mechanism of Action:
Monovisc works by replenishing and enhancing the natural lubrication and cushioning within your knee joint. In osteoarthritis, natural fluid (called synovial fluid) that helps your joint move smoothly and absorb shock becomes thinner and less effective, and its key component, hyaluronic acid (HA), is often reduced or of poorer quality. When Monovisc, which contains a highly purified form of HA, is injected into the knee, it essentially acts as a supplement to this natural fluid. By restoring the thickness and elastic properties of the synovial fluid, Monovisc helps to reduce friction between the bones, improve joint movement, and provide better shock absorption, ultimately leading to a decrease in pain and improved function for people with knee osteoarthritis.

Take Monovisc exactly as your doctor prescribes. Follow the instructions in the A Guide to Patients Brochure | monovisc.ca or the information leaflet that comes with your medicine. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Monovisc, discussing all possible aspects with your doctor or pharmacist is essential.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Monovisc, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Monovisc, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Joint pain (arthralgia)
• Joint swelling
• Injection site pain, swelling, redness, or discomfort
• Joint stiffness
• Headache
• Dizziness
• Back pain
• Itching, numbness, or tingling
• Nausea

Serious or rare side effects: Stop taking Monovisc and seek immediate medical attention if you experience any of the following:
• Severe allergic reactions: Symptoms such as hives, severe rash, difficulty breathing, or swelling of the face, lips, tongue, or throat.
• Serious infection at the injection site: Signs might include increased knee pain, warmth, redness, significant swelling, or drainage/pus around the injected joint.
• Bleeding within the joint.
• Pseudo-septic arthritis: A severe inflammatory reaction or "flare-up" in the joint, not caused by infection, but with similar symptoms like severe pain, redness, and swelling.
• Nerve damage: In very rare cases, injury to nerves around the injection site, leading to numbness, tingling, or persistent pain.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Monovisc.

Monovisc should not be used if:
• Known hypersensitivity (allergy) to hyaluronate preparations (such as Monovisc) or to any of its excipients (inactive ingredients). This is always an absolute contraindication for any medication.
• Known hypersensitivity (allergy) to gram-positive bacterial proteins. Monovisc's hyaluronic acid is often derived from bacterial fermentation, and a severe allergic reaction can occur if a patient is allergic to these proteins.
• Active infection or skin disease in the area of the injection site or in the affected knee joint. Injecting into an infected or compromised area carries a significant risk of spreading the infection into the joint, leading to potentially severe septic arthritis.

Drug Interactions:

Before taking Monovisc, discussing all potential risks and interactions with your doctor or pharmacist is essential. For complete and up-to-date information, refer to the official Monovisc website Canada: https://monovisc.ca/en/monovisc.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Monovisc may interact with other medicines, including:
• Disinfectants containing quaternary ammonium salts (e.g., benzalkonium chloride): These substances should not be used for skin preparation at the injection site, as they can cause the hyaluronate (the active ingredient in Monovisc) to precipitate or clump. This would prevent the Monovisc from working properly.

Pregnancy and Breastfeeding:

Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Monovisc. The safety of Monovisc during pregnancy or while breastfeeding has not been established through clinical studies. Therefore, if you are pregnant, planning to become pregnant, or breastfeeding, it is essential to discuss the potential risks and benefits with your healthcare provider.

Use in Children:

The safety and effectiveness of this viscosupplement have only been studied and established in adult populations for treating osteoarthritis. Therefore, there is no clinical data to support its use in pediatric patients, and it should not be administered to individuals under the age of 18.

Frequently Asked Questions about Monovisc at CanadaPharmacyOnline.com:

Why is Monovisc more affordable in Canada than in the United States?

Prescription drug prices, including Monovisc, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I buy over the counter from you?

No, Monovisc requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

Is there a limit on how many Monovisc injections I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Monovisc at once, per your doctor's prescription.

Blog Post:

Got Osteoarthritis? These Injections Can Erase Your Joint Pain

News:

Your Knees Might Be Aging Faster Than You Think (article published on May 25, 2025)

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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