Coveram (Amlodipine/Perindopril)

Name: Coveram
Brand: Servier
SKU: 7489
Availability: InStock

Type

Product

Manufacturer

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Dosage

Qty-Price (USD)

Type:

Product: Coveram

Manufacturer: Servier

Country: Turkey

Dosage: 5 mg/10 mg

Qty-Price (USD):

Type:

Product: Coveram (ON BACKORDER)

Manufacturer: Servier

Country: Turkey

Dosage: 5 mg/5 mg

Qty-Price (USD):

Type:

Product: Coveram

Manufacturer: Servier

Country: Turkey

Dosage: 10 mg/10 mg

Qty-Price (USD):

Type:

Product: Coveram

Manufacturer: Servier

Country: Turkey

Dosage: 10 mg/5 mg

Qty-Price (USD):

Generic Equivalent of Coveram

Type

Product

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Qty-Price (USD)

There is no generic product of Coveram.

Coveram Information

Coveram at CanadaPharmacyOnline.com

The manufacturer of brand-name Coveram (amlodipine/perindopril) is Servier (Turkey). Coveram is a combination blood pressure tablet containing amlodipine besylate and perindopril, manufactured by Servier and available in four strengths at this pharmacy.

The generic amlodipine/perindopril is currently unavailable (at this pharmacy).

Dosage:

Coveram is available in the following strengths and forms:
• Tablets: 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, and 10 mg/10 mg oral tablets.

The dose is one tablet taken once daily, preferably in the morning before a meal (on an empty stomach), as food can significantly reduce how well your body absorbs and activates perindopril. Your doctor will adjust your dosage based on your blood pressure response.

Usage:

Coveram is a combination blood pressure medication used to treat hypertension (high blood pressure). It contains two active ingredients that lower blood pressure through different but complementary mechanisms: amlodipine, a calcium channel blocker, and perindopril, an ACE inhibitor. Coveram may also be considered for patients with stable coronary artery disease, as perindopril has demonstrated cardiovascular protective benefits in this population.

High blood pressure often causes no symptoms but can lead to serious complications such as a heart attack, stroke, and kidney disease without proper treatment. Lifestyle changes such as regular exercise, quitting smoking, and a low-fat, low-salt diet can help this medication work more effectively. Take Coveram daily as directed by your doctor, even when you feel well.

Mechanism of Action Amlodipine, the active ingredient in Coveram, is a calcium channel blocker that relaxes the walls of blood vessels, allowing them to widen and making it easier for the heart to pump blood. This reduces blood pressure and can also relieve chest pain (angina) by increasing blood flow to the heart. Perindopril is an ACE inhibitor that works by blocking an enzyme the body uses to produce angiotensin II, a substance that causes blood vessels to tighten. By blocking this enzyme, perindopril helps blood vessels relax and lowers blood pressure. An additional benefit of combining the two drugs is that ankle swelling, sometimes caused by amlodipine, is significantly reduced when an ACE inhibitor such as perindopril is added.

Take Coveram exactly as your doctor prescribes, according to the instructions in the product monograph. For best results, do not take Coveram with food; take it consistently before breakfast.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Coveram, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Coveram (amlodipine/perindopril). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Coveram; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Cough (dry, persistent)
• Fatigue
• Flushing
• Headache
• Nausea
• Stomach upset
• Swelling of the ankles or feet (edema)

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Angioedema: Swelling of the face, lips, tongue, or throat, or sudden difficulty breathing or swallowing. Stop Coveram immediately and inform your doctor immediately.
• High Potassium: Muscle weakness or an abnormal heartbeat. The perindopril component can raise potassium levels.
• Jaundice (Liver Problems): Yellowing of the skin or eyes, dark urine, or severe stomach pain.
• Low Blood Pressure: Severe dizziness or fainting, particularly after the first dose or if you are dehydrated.
• Worsening Chest Pain or Heart Attack: Patients with heart disease may experience increased angina or a heart attack when starting or increasing the amlodipine dose.
• Worsening Kidney Function: Decreased urine output or rapid weight gain with swelling.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Coveram, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Coveram/amlodipine/perindopril if:
• Allergies: You have a known hypersensitivity to amlodipine, perindopril, any other ACE inhibitor or calcium channel blocker, or any tablet ingredient.
• Angioedema History: You have a history of angioedema related to previous ACE inhibitor treatment, or hereditary or unexplained angioedema.
• Heart Failure Complications: Coveram is strictly contraindicated if you have cardiogenic shock, severe aortic stenosis, or unstable heart failure immediately following a heart attack. (Note: It is safe and beneficial for stable chronic heart failure, but must be avoided during acute cardiac crises.
• Diabetes with Aliskiren: You are taking aliskiren (Rasilez) and have diabetes.
• Sacubitril/Valsartan (Entresto): Do not take Coveram within 36 hours of switching to or from sacubitril/valsartan.

Tell your doctor about all of your medical conditions, past and present, before starting Coveram. This is crucial as certain conditions affect the drug’s safety.
• Diabetes
• Heart disease or a recent heart attack
• High potassium levels
• Low-salt diet
• Kidney or liver disease (including if you are on dialysis)

Drug Interactions:

Before taking Coveram, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please refer to the product monograph at https://pdf.hres.ca/dpd_pm/00054186.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Coveram. Coveram may interact with other medicines, including but not limited to:
• Aliskiren: Increases the risk of low blood pressure, high potassium, and kidney failure.
• Diuretics (water pills): May cause an excessive drop in blood pressure.
• Grapefruit and Grapefruit Juice: Avoid completely. Grapefruit blocks the metabolism of amlodipine, which can dangerously increase the drug levels in your body and cause a severe drop in blood pressure.
• Lithium: Perindopril can raise lithium levels in the blood to potentially harmful levels.
• NSAIDs (e.g., ibuprofen, naproxen): May reduce the blood pressure-lowering effect of Coveram and can worsen kidney function.
• Other antihypertensive drugs.
• Potassium supplements or potassium-sparing diuretics (e.g., spironolactone)
• Potassium-containing salt substitutes

Pregnancy and Breastfeeding:

Coveram can cause serious harm or death to an unborn baby, particularly if taken during the second or third trimester of pregnancy. Stop taking Coveram as soon as you know you are pregnant and contact your doctor immediately. Women who are planning to become pregnant should discuss alternative blood pressure medications with their doctor before stopping Coveram. It is unknown if perindopril passes into human breast milk. Because of potential risks to the infant, alternative treatments are preferred while breastfeeding. Discuss the risks and benefits with your doctor.

Use in Children:

Coveram is not recommended for patients under 18 years of age. The safety and efficacy in this age group have not been established.

Frequently Asked Questions about Coveram at Canada Pharmacy Online>h2>

Why is Coveram more affordable in Canada than in the United States?

Prescription drug prices, including Coveram, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Coveram tablets I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of Coveram as per your doctor’s prescription.

Can I buy Coveram from you over the counter?

No, Coveram requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Coveram?

No, the generic alternative is currently unavailable (at this pharmacy).

Blog Post:

Natural Ways to Lower Your Blood Pressure

Latest News:

Effectiveness of an amlodipine and perindopril arginine-based strategy for hypertension management – Pan African Medical Journal (published December 2025)

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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