Accrufer (Ferric Maltol)

Name: Accrufer
Brand: Norgine Pharmaceuticals
SKU: 7813
Availability: InStock

Type

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Dosage

Qty-Price (USD)

Type:

Product: Accrufer Capsule

Manufacturer: Norgine Pharmaceuticals

Country: United Kingdom

Dosage: 30 mg

Qty-Price (USD):

Type:

Product: Accrufer Capsule

Manufacturer: Kye Pharmaceuticals Inc.

Country: Canada

Dosage: 30 mg

Qty-Price (USD):

Generic Equivalent of Accrufer

Type

Product

Manufacturer

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Qty-Price (USD)

There is no generic product of Accrufer.

Accrufer Information

Accrufer at CanadaPharmacyOnline.com

The brand Accrufer (ferric maltol) is marketed by Shield Therapeutics plc globally, and co-commercialized in the United States with Viatris Inc. In Canada, it is licensed to KYE Pharmaceuticals Inc. Accrufer is available as a brand-name medication; there is currently no therapeutically equivalent generic formulation of ferric maltol available.

Dosage

Accrufer, containing ferric maltol, is commonly available as oral capsules with 30 mg of iron at this pharmacy. Your doctor will determine the appropriate dose and duration based on your individual needs and medical conditions.

Usage

Accrufer (ferric maltol) is an iron replacement product indicated for the treatment of iron deficiency in adults, including those with iron deficiency anemia who may be unresponsive or intolerant to other oral iron preparations. It can be used in patients with underlying conditions such as inflammatory bowel disease (IBD) or chronic kidney disease (CKD). However, Accrufer should be avoided during active IBD flares due to the potential risk of increased gastrointestinal inflammation.
• Iron Deficiency: A condition where the body does not have enough iron, which is essential for making hemoglobin, a protein in red blood cells that carries oxygen. Iron deficiency can lead to a range of symptoms, including fatigue, weakness, and shortness of breath.
• Iron Deficiency Anemia: A more severe form of iron deficiency where the lack of iron leads to a decrease in the number of red blood cells or the amount of hemoglobin in them.

Mechanism of Action Accrufer (ferric maltol) is a novel, non-salt oral iron therapy. It is a stable complex of ferric iron and maltol. The "maltol shield" protects the iron from the stomach environment, allowing it to remain tightly bound as it passes through. The iron is absorbed in the small intestine, which limits free iron and is thought to lower the risk of gastrointestinal damage and irritation often associated with other oral iron supplements. By facilitating the absorption of iron, Accrufer helps replenish the body's iron stores, supporting the production of hemoglobin and red blood cells. Unabsorbed iron is excreted in the stool.

Take Accrufer exactly as your doctor prescribes, following the instructions in the official Product Monograph from Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Accrufer, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Accrufer, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects - These are some common side effects of Accrufer, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abdominal discomfort or distension
• Abdominal pain
• Constipation
• Diarrhea
• Discoloured feces (dark green or black stools, common with iron supplements)
• Flatulence (gas)
• Nausea
• Vomiting

Serious Side Effects - These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions: Rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing.
• Increased risk of inflammatory bowel disease (IBD) flare: Avoid taking Accrufer if you have IBD and are experiencing a flare.
• Iron overload (hemochromatosis or hemosiderosis): Excessive accumulation of iron in the body. Your healthcare provider should check your iron levels before and during treatment. Symptoms may include fatigue, joint pain, abdominal pain, and skin discoloration.
• Accidental overdose in children: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep Accrufer out of reach of children.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Accrufer, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Accrufer should not be used if you:
• Are allergic (hypersensitive) to ferric maltol or any of the ingredients in the formulation.
• Have hemochromatosis or other iron overload syndromes.
• Are receiving repeated blood transfusions, as this may result in iron overload.

Tell your doctor about all of your medical conditions, past and present, before starting Accrufer. This is crucial because certain conditions affect whether Accrufer is right for you. These conditions may include, but are not limited to:
• Inflammatory bowel disease (IBD), especially if you are experiencing an active flare.
• Liver or kidney disease (discuss with your doctor for appropriate monitoring).

Pregnancy and Breastfeeding

Current information suggests that Accrufer may be considered safe during pregnancy when prescribed by a healthcare professional for iron deficiency or iron deficiency anemia, as iron deficiency during pregnancy can lead to complications. However, it is essential to discuss your circumstances with your doctor. It is not known whether ferric maltol is excreted in human breast milk. Consult your doctor to weigh the potential risks and benefits before using Accrufer while breastfeeding.

Use in Children The safety and effectiveness of Accrufer have not been established in pediatric patients (under 18 years of age). While the product monograph states, "Children—Use and dose must be determined by your doctor," other sources indicate that appropriate studies have not been performed in this population and safety and efficacy have not been established. Accidental overdose of iron-containing products is a leading cause of death from poisoning in children under 6. Keep Accrufer in a safe place and out of the reach of children.

Drug Interactions

Before taking Accrufer, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Product Monograph from Canada, available through Health Canada’s Drug Product Database.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Accrufer.

Potential drug interactions with Accrufer (ferric maltol) may include:
• Other oral iron tablets or supplements containing iron: Concurrent use is generally not recommended as it may lead to iron overload.
• Antacids: May decrease the absorption of iron. Take Accrufer at a different time of day than antacids, typically separated by 2-4 hours.
• Certain medications used to treat bone conditions (e.g., alendronate or risedronate) may interact with iron absorption. Take Accrufer at a different time of day from these medications.
• Certain medications for HIV or Hepatitis: Potential interactions.
• Certain medications used to treat stomach problems (e.g., cimetidine, famotidine, omeprazole, lansoprazole) may interfere with iron absorption.
• Carbidopa/Levodopa: Iron may decrease the absorption of levodopa.
• Cholestyramine: May decrease iron absorption.
• Deferoxamine: Used to treat iron overload; concurrent use with iron supplements is illogical.
• Dimercaprol: Used for heavy metal poisoning; concurrent use with iron supplements is contraindicated.
• Methyldopa: Iron may reduce the effectiveness of methyldopa.
• Quinolone antibiotics (e.g., ciprofloxacin, levofloxacin, moxifloxacin): Iron may decrease the absorption of these antibiotics. Take Accrufer at least 2 hours before or 4 hours after taking quinolone antibiotics.
• Tetracycline antibiotics (e.g., doxycycline, minocycline, tetracycline): Iron may decrease the absorption of these antibiotics. Take Accrufer at least 2 hours before or 4 hours after taking tetracycline antibiotics.
• Thyroid hormones (e.g., levothyroxine): Iron may decrease the absorption of thyroid hormones. Take Accrufer at least 4 hours apart from thyroid hormones.
• Zinc supplements: May compete with iron for absorption.

Food Interactions:
• Food (especially dairy products, coffee, and tea) can decrease the absorption of iron. Take Accrufer 1 hour before or 2 hours after a meal for optimal absorption.

Frequently Asked Questions about Accrufer at CanadaPharmacyOnline:

Why is Accrufer more affordable in Canada than in the United States?

Prescription drug prices, including Accrufer, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many capsules I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Accrufer at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Accrufer requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to take Accrufer?

Accrufer should be taken twice daily, 1 hour before or 2 hours after a meal for optimal absorption. If you take other medications or supplements that interact with iron absorption, discuss the best timing with your doctor or pharmacist.

Blog Post

The Best Iron Supplements Infographic

Latest News:

Updates in the Management of Iron Deficiency Anemia (article published on April 28th, 2025)

Similar Drugs in the category of Iron Supplements:

Palafer Ferrous Gluconate Ferriprox HemeBoost Safe Plus

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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