Adcirca (Tadalafil)

Name: Adcirca
Brand: Eli Lilly
SKU: 7031
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Adcirca

Manufacturer: Eli Lilly

Country: Canada

Dosage: 20 mg

Qty-Price (USD):

Type:

Product: Adcirca

Manufacturer: Eli Lilly

Country: Australia

Dosage: 20 mg

Qty-Price (USD):

Generic Equivalent of Adcirca

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Tadalafil

Manufacturer: Generic

Country: Canada

Dosage: 20 mg

Qty-Price (USD):

Adcirca Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on May 23, 2025.

Adcirca and Tadalafil at CanadaPharmacyOnline.com

Adcirca (tadalafil), originally developed and manufactured by Eli Lilly and Company, is available in several countries, including Canada and Australia.

Generic tadalafil is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Tadalafil:

Generic tadalafil contains the same active ingredient as the brand-name Adcirca. It is required to meet the same safety, effectiveness, and quality standards.

This means it is designed to work in the same way as Adcirca. While specific bioequivalence studies are conducted to ensure generic medications have comparable absorption rates and overall effects, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have questions about using generic tadalafil.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Adcirca (tadalafil) is typically available as 20 mg oral tablets for treating pulmonary arterial hypertension (PAH).

Your doctor will determine the appropriate dosage based on your needs and medical conditions.

Usage:

Adcirca (tadalafil) is a prescription medication used to treat pulmonary arterial hypertension (PAH). PAH is a condition with high blood pressure in the lungs' arteries. Tadalafil works by relaxing the blood vessels in the lungs, which allows blood to flow more easily and reduces the workload on the heart. This can improve your ability to exercise and reduce symptoms such as shortness of breath and fatigue. Your doctor will determine the appropriate dosage and duration of treatment with tadalafil based on the severity of your PAH and your response to the medication. It is crucial to follow your doctor's prescribed dosing regimen.

For more information, refer to the product labeling information, https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022332Orig1s011lbl.pdf

Mechanism of Action:
Adcirca (tadalafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). In pulmonary arterial hypertension (PAH), elevated cGMP levels in the pulmonary vascular smooth muscle lead to vasodilation. PDE5 is the predominant phosphodiesterase in the pulmonary vasculature, and its inhibition by tadalafil increases cGMP levels, resulting in relaxation of the pulmonary arteries and a reduction in pulmonary vascular resistance and pressure.

Use Adcirca exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor, following the instructions in the patient information leaflet and the instructions for your medication. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Adcirca, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Adcirca, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Adcirca, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Back pain
• Diarrhea
• Flushing (feeling of warmth)
• Headache
• Indigestion
• Muscle aches
• Nasal congestion
• Nausea
• Nosebleeds
• Pain in the arms or legs
• Sore throat
• Upset stomach

Serious or rare side effects: Stop taking Adcirca and seek immediate medical attention if you experience any of the following:
• Chest pain or pressure
• Changes in vision or sudden vision loss (possible sign of non-arteritic anterior ischemic optic neuropathy (NAION)
• Priapism (erection lasting more than four hours)
• Ringing in the ears, sudden decrease or loss of hearing
• Severe allergic reaction (rash, itching, swelling, difficulty breathing)
• Symptoms of pulmonary veno-occlusive disease (PVOD) such as increased shortness of breath, cough, or fatigue

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Adcirca.

Adcirca should not be used if:
• You are allergic to tadalafil or any of the other ingredients in Adcirca.
• You are taking nitrates for chest pain (angina) or other heart conditions. Combining tadalafil with nitrates can cause a sudden and serious decrease in blood pressure.

Tell your doctor about all of your medical conditions, past and present, before starting Adcirca. This is crucial because certain conditions can affect whether Adcirca is right for you. These conditions may include, but are not limited to:
• Bleeding problems
• Conditions predisposing to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia)
• Deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie's disease)
• Heart problems (e.g., angina, heart failure, irregular heartbeat)
• High or low blood pressure
• Kidney problems
• Liver problems
• Peptic ulcers
• Pulmonary hypertension secondary to other conditions (the efficacy of tadalafil in this setting may be limited)
• Retinitis pigmentosa (an eye disease)
• Stroke

Drug Interactions:

Before taking Adcirca, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Adcirca product monograph from Canada, https://pi.lilly.com/ca/adcirca-ca-pm.pdf

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Adcirca may interact with other medicines, including but not limited to alpha-blockers (used to treat high blood pressure or prostate problems), antifungal medications (e.g., ketoconazole, itraconazole), certain antibiotics (e.g., clarithromycin, erythromycin), HIV protease inhibitors (e.g., ritonavir), nitrates, Guanylate cyclase stimulators (e.g., riociguat), other medications for pulmonary hypertension, or rifampin (an antibiotic)

Pregnancy and Breastfeeding:

It is not known if Adcirca is safe for use during pregnancy or breastfeeding. Discuss the potential risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

Adcirca is not indicated for use in children. Safety and effectiveness have not been established in pediatric patients.

Frequently Asked Questions about Adcirca at CanadaPharmacyOnline.com:

Why is Adcirca more affordable in Canada than in the United States?

Prescription drug prices, including Adcirca, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I buy over the counter from you?

No, Adcirca requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

How long does it take for Adcirca to work?

Adcirca starts working to relax the blood vessels in the lungs relatively quickly. However, it may take several days or weeks of consistent use to experience the full benefits, such as improved exercise capacity and reduced symptoms of pulmonary arterial hypertension.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Adcirca at once, per your doctor's prescription.

What should I do if I miss a dose?

If you miss a dose of Adcirca, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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