Azopt Drops (Brinzolamide)

Name: Azopt Drops
Brand: Novartis
SKU: 0149
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Azopt Drops

Manufacturer: Novartis

Country: Canada

Dosage: 1 %/5 ml

Qty-Price (USD):

Type:

Product: Azopt Drops

Manufacturer: Alcon

Country: Australia

Dosage: 1 %/5 ml

Qty-Price (USD):

Generic Equivalent of Azopt Drops

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Brinzolamide

Manufacturer: Generic

Country: United Kingdom

Dosage: 1 %/5 ml

Qty-Price (USD):

Azopt Drops Information

medically reviewed by Carol Hou (BSc. Pharm) on July 2, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

AZOPT and Brinzolamide Ophthalmic Suspension at CanadaPharmacyOnline.com

Brand AZOPT is manufactured and/or marketed by Alcon (now part of Novartis) in various global locations, including Australia. Novartis also distributes it in Canada.

Generic brinzolamide ophthalmic suspension is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Brinzolamide Ophthalmic Suspension:

Generic brinzolamide ophthalmic suspension contains the same active ingredient as brand-name AZOPT and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as AZOPT. Studies have shown that generic brinzolamide ophthalmic suspension is bioequivalent to brand-name AZOPT, meaning they have similar absorption rates and reach similar concentrations in the bloodstream. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts

Dosage:

AZOPT and generic brinzolamide ophthalmic suspension, the most common strength is 1% w/v, which means that the concentration of the active ingredient, brinzolamide, is 1 gram per 100 mL. Each bottle typically contains 5 ml (milliliters) of this suspension (at this pharmacy).

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

AZOPT (brinzolamide ophthalmic suspension) is a prescription eye drop to lower elevated intraocular pressure (IOP) in individuals with ocular hypertension or open-angle glaucoma. It plays a vital role in managing these conditions and can be used as a standalone treatment or alongside other topical or systemic medications. It's important to recognize that while AZOPT effectively controls IOP in glaucoma and ocular hypertension, it is not a cure and requires consistent use as directed by an ophthalmologist to maintain its therapeutic effects.

Mechanism of Action:
Brinzolamide belongs to a class of medications known as topical carbonic anhydrase inhibitors. It works by inhibiting the enzyme carbonic anhydrase, which produces aqueous humor. By blocking this enzyme in the ciliary processes of the eye, brinzolamide reduces the rate of aqueous humor secretion, thereby lowering the intraocular pressure.

Take AZOPT exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking AZOPT, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with AZOPT (brinzolamide ophthalmic suspension). It is not an exhaustive list, and individual reactions can vary.

Common side effects (may affect up to 1 in 10 people): These are some common side effects of AZOPT, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms. Eye-related side effects such as:
• Blurred vision (temporary)
• Dry eye
• Eye discharge
• Eye discomfort, pain, or itchiness
• Feeling like something is in the eye
• Increased tears
• Inflammation of the eyelid (blepharitis)
• Inflammation of the cornea (keratitis)
• Redness of the eye
• Sensitivity to light (photophobia)

Less common side effects (may affect up to 1 in 100 people):
• Burning, stinging, or discomfort when the medicine is applied
• Decreased vision
• Dizziness
• Dry mouth
• Eye pain
• Eyes sensitive to light
• Muscle pain
• Red, sore eyes
• Sneezing

Other side effects may include:
• Headache
• Runny or stuffy nose
• Skin inflammation (dermatitis)

Rare side effects (may affect up to 1 in 1,000 people):
• Chest pain
• Crusting in the corner of the eye
• Difficulty swallowing
• Double vision
• Fast heartbeat
• Hives
• Itching, swelling, or other signs of eye or eyelid irritation
• Kidney pain
• Muscle stiffness, tension, or tightness
• Shortness of breath
• Sore throat
• Tightness in the chest
• Wheezing

Taste-related side effects:
Unusual, bitter, or sour taste in the mouth (this usually lasts only a few minutes)

Side effects with unknown frequency:
• Abdominal or stomach pain
• Acid or sour stomach
• Blistering, peeling, or loosening of the skin
• Body aches or pain
• Congestion
• Chills
• Clay-colored stools
• Confusion
• Dark urine
• Difficult or labored breathing
• Fever with or without chills
• General feeling of tiredness or weakness
• Hair loss or thinning of the hair
• Heartburn
• Hoarseness
• Indigestion
• Irregular heartbeat
• Joint or muscle pain
• Muscle cramps or pain
• Numbness, tingling, pain, or weakness in the hands or feet
• Painful or difficult urination
• Red or irritated eyes
• Red skin lesions, often with a purple center
• Seizures
• Sores, ulcers, or white spots on the lips or in the mouth
• Stomach discomfort, upset, or pain
• Swollen or painful glands
• Trembling
• Tender, swollen glands in the neck
• Unpleasant breath odor
• Unusual bleeding or bruising
• Vomiting of blood
• Voice changes
• Weakness and heaviness of the legs
• Yellow eyes or skin

Serious allergic reaction: Seek immediate medical attention or call emergency services if you experience any of the following: • Difficulty breathing or wheezing
• Feeling lightheaded or fainting
• Fever
• Racing heart
• Severe skin rash, hives, or blisters
• Swelling of the face, lips, tongue, or throat

Contraindications:

The following is not an exhaustive list of contraindications. Before starting AZOPT, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

AZOPT should not be used if:
• You are allergic to brinzolamide, any of the other ingredients in AZOPT, or to sulfonamide medications (sulfa drugs)
• You are taking oral carbonic anhydrase inhibitors (e.g., acetazolamide, methazolamide)
• You have a condition called hyperchloremic acidosis (which is increased acidity of the blood) • You have severe kidney problems

Tell your doctor about your medical conditions, past and present, before starting AZOPT. This is crucial because certain conditions affect whether AZOPT is right for you. These conditions may include, but are not limited to:
• Acute Angle-Closure Glaucoma: AZOPT is generally not the primary treatment for acute angle-closure glaucoma attacks. While it may be considered for long-term IOP management after the acute phase is controlled, its efficacy and safety during an active acute attack have not been specifically studied.
• Compromised Corneas: Topical carbonic anhydrase inhibitors like AZOPT can affect the corneal endothelium and its fluid regulation. Careful monitoring is recommended in patients with compromised corneal endothelium, such as those with diabetes mellitus, corneal dystrophies, or a history of corneal surgery. AZOPT may increase the risk of corneal edema or decompensation.
• Hepatic Impairment: AZOPT has not been extensively studied in patients with significant liver impairment. Caution is advised due to the potential for altered metabolism and clearance of the systemically absorbed drug or its metabolites, which could lead to increased systemic exposure or unpredictable effects.
• Renal Impairment: Caution is advised when using AZOPT in patients with moderate to severe renal impairment due to the increased risk of systemic metabolic acidosis resulting from impaired bicarbonate reabsorption in the kidneys.
• Sulfonamide Allergy: AZOPT is a sulfonamide; systemic absorption can occur with topical administration. The same adverse reactions seen with oral sulfonamides may occur with AZOPT. If signs of serious reactions or hypersensitivity occur, discontinue use immediately.

Contact Lenses:
Remove contact lenses before using AZOPT and wait at least 15 minutes before reinserting them, as soft contact lenses can absorb the preservative in AZOPT and may cause irritation.

Driving and Operating Machinery:
AZOPT may cause temporary blurred vision or other visual disturbances. Patients should wait until their vision clears before driving or using machinery. Nervous system disorders have also been reported, which may affect these abilities.

Drug Interactions:

Before taking AZOPT, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the AZOPT prescribing information.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. AZOPT may interact with other medicines, but is not limited to:
• Oral Carbonic Anhydrase Inhibitors: AZOPT with oral carbonic anhydrase inhibitors is generally not recommended. There's a potential for an additive effect on the systemic side effects of carbonic anhydrase inhibition. This could increase the risk of side effects affecting the whole body. (Examples include acetazolamide, methazolamide, dichlorphenamide)
• Other Topical Ophthalmic Drugs: While Azopt can be used with other topical eye medications to lower intraocular pressure, it's important to administer them at least 10 minutes apart. This helps to prevent the first eye drop from being washed away by the second.
• Salicylates: High doses of oral salicylates may interact with carbonic anhydrase inhibitors like Azopt. This combination could increase the risk of electrolyte problems and acid-base imbalances in the body. (Examples include aspirin, bismuth subsalicylate, and other salicylate-containing medications)

Pregnancy and Breastfeeding:

The safety of AZOPT during pregnancy and breastfeeding has not been fully established. It is generally not recommended during pregnancy or in women of childbearing potential who are not using contraception. It is unknown if brinzolamide passes into breast milk. Discuss with your doctor if you are pregnant or breastfeeding before using AZOPT.

Frequently Asked Questions about AZOPT at Canada Pharmacy Online:

Why is AZOPT more affordable in Canada than in the United States?

Prescription drug prices, including AZOPT, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many AZOPT I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of AZOPT at once, per your doctor's prescription.

Can I buy over the counter from you?

No, AZOPT requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for AZOPT?

There is a generic alternative for this product called brinzolamide ophthalmic suspension.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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