Daliresp (Roflumilast)

Name: Daliresp
Brand: AstraZeneca
SKU: 6776
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Daliresp

Manufacturer: AstraZeneca

Country: Canada

Dosage: 500 mcg

Qty-Price (USD):

Type:

Product: Daliresp

Manufacturer: AstraZeneca

Country: United Kingdom

Dosage: 500 mcg

Qty-Price (USD):

Generic Equivalent of Daliresp

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Roflumilast

Manufacturer: Generic

Country: India

Dosage: 500 mcg

Qty-Price (USD):

Daliresp Information

medically reviewed by Carol Hou (BSc. Pharm) on April 24, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Daliresp and Roflumilast at CanadaPharmacyOnline.com

Brand Daliresp, manufactured by AstraZeneca, is available in Canada and the United Kingdom.

The generic version, roflumilast, is sourced from India and verified to meet regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Rolfumilast

Generic roflumilast contains the same active ingredient as brand-name Daliresp and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Daliresp. Studies have shown that generic roflumilast is bioequivalent to brand-name Daliresp, meaning they have similar absorption rates and reach similar concentrations in the bloodstream. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions. If you have any questions about using generic roflumilast, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, please visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand Daliresp and generic roflumilast are available in strengths of 500 mcg.

Your doctor can determine our safe and effective dosage based on your individual needs.

Usage:

Daliresp (roflumilast) is a prescription medication to reduce the risk of flare-ups or worsening symptoms (exacerbations) in adults with severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis and history of exacerbations. Roflumilast is not a bronchodilator and should not be used to treat acute breathing problems

Daliresp does not cure (COPD). Consult a healthcare professional with any questions about any medication or respiratory health. (source: the product labeling information).

Mechanism of Action:
Daliresp is a phosphodiesterase-4 (PDE4) inhibitor. It works by blocking a specific enzyme, called PDE4, which is involved in causing inflammation in people with COPD. By blocking this enzyme, Daliresp helps to increase the levels of an important substance in lung cells, which then calms down the inflammation. This action is not like an inhaler that opens your airways right away; instead, Daliresp is a daily medication that aims to prevent flare-ups of your COPD over time. Take Daliresp exactly as your doctor prescribes and refer to the official full prescribing information. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Daliresp, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Common side effects – The following are some common side effects of Daliresp, but others are possible. Contact your doctor if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Diarrhea
• Weight loss
• Nausea
• Headache
• Back pain
• Flu-like symptoms (upper respiratory infection)
• Insomnia
• Dizziness
• Decreased appetite

Serious or rare side effects: Stop taking Daliresp and seek immediate medical attention if you experience any of the following:
• Vomiting
• Abdominal pain
• Loss of appetite
• Tremors
• Anxiety
• Mental Health Problems – Daliresp can cause or worsen mental health problems, including depression, anxiety, and suicidal thoughts or behavior. It’s crucial to report any changes in mood or thought to your doctor immediately.
• Severe Allergic reactions: These can include rash, itching, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.
• Liver problems: Daliresp can affect liver function. Your doctor may monitor your liver enzymes with blood tests.
• Severe skin reactions: Although rare severe skin reactions, including Stevens-Johnson syndrome, have been reported.

Individual reactions can vary. It is crucial to discuss potential side effects and risks with your doctor for a complete and up-to-date list

Contraindications:

The following is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present and all the medications you are taking with your doctor before starting Daliresp.

Daliresp is CONTRAINDICATED in the following situations and should not be used if:
• You have moderate to severe liver impairment (Child-Pugh Class B or C)
• Hypersensitivity: if you have a known allergy or hypersensitivity to roflumilast or any of the components in the Daliresp formulation.

Inform your doctor if you have any of the following pre-existing medical conditions, as they may affect whether Daliresp is right for you:
• Mental health problems
• Unexplained weight loss
• Gastrointestinal disorders
• Immunological diseases
• Severe infections
• Cancer
• Immunosuppressive therapies
• Lactase deficiency

The following summarizes potential drug interactions. Before taking Daliresp, it is essential to discuss all potential risks and interactions with your doctor or pharmacist.
• Strong CYP3A4 inhibitors: Daliresp is metabolized by the CYP3A4 enzymes. Strong inhibitors of this enzyme such as ketoconazole, itraconazole, clarithromycin, and ritonavir, can significantly increase roflumilast levels in the body, leading to increased side effects. Concurrent use is generally not recommended. If unavoidable, your doctor may need to adjust the daliresp dosage.
• Strong CYP3A4 inducers; Drugs that strongly induce CYP3A4. Such as rifampin, carbamazepine, phenytoin, and St. John’s wort, can decrease roflumilast levels making it less effective. Concurrent use should be avoided.
• Theophylline: Both Daliresp and theophylline can affect the cardiovascular system. Caution is advised when these drugs are used together, and monitoring may be necessary.
• Other PDE4 inhibitors combining Daliresp with other phosphodiesterase-4 (PDE4) inhibitors is not recommended due to the potential for additive side effects.
• Dizziness and Drowsiness Daliresp may cause dizziness or drowsiness. Avoid driving, operating machinery, or engaging in activities that require alertness until you understand how it affects you.
• Alcohol: Excessive alcohol consumption can increase the risk of serious side effects and should be discussed with your doctor.

Drug interactions:

Before taking Daliresp (roflimulast) discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, consult the official Daliresp website, https://www.daliresp.com/, and discuss any concerns with your healthcare provider.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter drugs, vitamins, and herbal supplements.

Pregnancy and Breastfeeding:

If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking Daliresp.

Frequently Asked Questions about Daliresp at Canada Pharmacy online:

Why is Daliresp more affordable in Canada than in the United States?

Prescription drug prices, including Daliresp, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations and differing market dynamics. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or for the ordering process, visit our How to Order page.

Is there a limit on how many Daliresp tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Daliresp at one time, as per your doctor's prescription.

Can I buy Daliresp over the counter from you?

No, Daliresp requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Daliresp?

Yes, there is a generic alternative for this product, called roflumilast.

Latest News:

Protein In The Nose Provides Information About COPD, Reports Research (article published on April 9, 2025)

The generic alternative is not manufactured by the company that makes the brand product.

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This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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