Detrol (Tolterodine)

Name: Detrol
Brand: Pfizer
SKU: 0345
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Detrol

Manufacturer: Pfizer

Country: United Kingdom

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Detrol

Manufacturer: BGP Pharma

Country: Canada

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Detrol

Manufacturer: Pfizer

Country: United Kingdom

Dosage: 2 mg

Qty-Price (USD):

Generic Equivalent of Detrol

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Tolterodine

Manufacturer: Generic

Country: Canada

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Tolterodine

Manufacturer: Generic

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Type:

Product: Tolterodine Tablet

Manufacturer: Generic

Country: United Kingdom

Dosage: 2 mg

Qty-Price (USD):

Detrol Information

medically reviewed by Carol Hou (BSc. Pharm) on May 8, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Detrol and Tolterodine at CanadaPharmacyOnline.com

Brand Detrol is marketed by Pfizer in Canada and the United Kingdom. In Canada, Detrol is also marketed by BGP Pharma.

Generic Tolterodine is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Tolterodine

Generic tolterodine contains the same active ingredient as brand-name Detrol and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Detrol. Studies have demonstrated bioequivalence between generic and brand-name Detrol, demonstrating comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic tolterodine.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca

Dosage:

Brand Detrol and generic tolterodine are available in strengths of 1 mg and 2 mg capsules.

Your doctor will determine your safe and effective dosage based on your individual needs.

Usage:

Detrol is a prescription medication that helps adults who have an overactive bladder. If you find yourself needing to go to the bathroom very often, have a strong urge to go that’s hard to control or sometimes leaking urine because you can’t go to the toilet in time, Detrol can help it.

Mechanism of Action:
Detrol (tolterodine) functions by blocking the action of a natural body chemical called acetylcholine on specific receptors, mainly in your bladder. Think of these receptors as switches that tell your bladder muscle to squeeze. By blocking these switches, Detrol helps your bladder muscle relax, reducing the sudden urges to go and how often you need to urinate. Instead of decreasing how much your bladder can hold, Detrol actually helps it hold more urine comfortably before you feel a strong urge, giving you better control and fewer leaks.

It is crucial to take Detrol exactly as your doctor prescribes and read the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Detrol (tolterodine), it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Common side effects – These are some frequently reported side effects of Detrol (tolterodine), but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or if you experience any other concerning symptoms.
• Dry mouth
• Headache
• Dizziness
• Constipation
• Dry eyes
• Blurred vision
• Indigestion (dyspepsia)
• Abdominal pain
• Fatigue

Serious Side effects – Stop taking Detrol and seek immediate medical attention if you experience any of the following:
• Severe allergic reactions: Symptoms may include rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing, or swallowing.
• Chest pain or irregular heartbeat (palpitations, tachycardia): Detrol can sometimes affect the heart, especially in individuals with pre-existing heart conditions.
• Difficulty urinating (urinary retention): While the goal of Detrol is to improve bladder control, in some cases, it can paradoxically lead to difficulty emptying the bladder completely.
• Heatstroke: Decreased sweating due to anticholinergic effects can increase the risk of overheating in hot environments or during strenuous exercise.
• Confusion or hallucinations: These central nervous system effects are more likely in elderly individuals or those with pre-existing cognitive impairment.
• Angle-closure glaucoma: In individuals with narrow angles in their eyes, anticholinergic drugs like Detrol can potentially trigger an acute angle-closure glaucoma attack, causing sudden eye pain, blurred vision, and halos around lights.

Individual reactions can vary. It is crucial to discuss potential side effects and risks with your doctor for a complete and up-to-date list.

Contraindications:

The following is not an exhaustive list of contraindications. It is crucial to discuss all of your medical conditions, past and present, and all the medications you are taking with your doctor or pharmacist before taking Detrol (tolterodine).

Detrol (tolterodine) is CONTRAINDICATED in the following situations and should not be used if:
• Urinary retention: Detrol should not be used in individuals who are unable to empty their bladder. The medication works by relaxing bladder muscles, which could worsen urinary retention
• Hypersensitivity to tolterodine or its excipients: Individuals who have had an allergic reaction to tolterodine or any of the inactive ingredients in the formulation should not take Detrol.

Tell your doctor about all your medical conditions, past and present, before starting Detrol. This is crucial because certain conditions can affect whether Detrol is right for you. These conditions may include but are not limited to:
• Uncontrolled narrow-angle glaucoma: Detrol can worsen this condition. In narrow-angle glaucoma, the flow of fluid in the eye is blocked, increasing pressure. Anticholinergic drugs like Detrol can further narrow the angle, potentially leading to an acute glaucoma attack.
• Myasthenia gravis: This is a neuromuscular disorder characterized by muscle weakness. Anticholinergic medications like Detrol can potentially exacerbate the symptoms of myasthenia gravis.
• Severe ulcerative colitis: Detrol can slow down the movement of the digestive system, which could worsen the symptoms of severe ulcerative colitis, including toxic megacolon.
• Toxic megacolon: This is a serious complication of inflammatory bowel disease. The slowing of the digestive system caused by anticholinergics like Detrol can worsen this condition.

Drug Interactions:

Before taking Detrol, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up to date information, refer to the official prescribing information (package insert): https://www.pfizer.com/products/product-detail/detrol

Drugs that can increase Detrol levels:

Strong CYP3A4 inhibitors: Tolterodine is metabolized by the cytochrome P450 3A4 (CYP3A4) enzyme. Co-administration with strong CYP3A4 inhibitors can significantly increase tolterodine levels in the blood, potentially leading to an increased risk of side effects. Examples of strong CYP3A4 inhibitors include:
o Ketoconazole
o Itraconazole
o Clarithromycin
o Erythromycin
o Ritonavir
o Grapefruit juice (in large quantities): While not a drug, it can inhibit CYP3A4 in the gut.

Caution and potentially a lower dose of Detrol are usually recommended when used with strong CYP3A4 inhibitors.

Moderate CYP3A4 inhibitors: Moderate inhibitors may also increase tolterodine levels, but the effect might be less pronounced. Caution is still advised. Examples include:
o Fluconazole
o Diltiazem
o Verapamil

Drugs that can decrease Detrol levels:

Strong CYP3A4 inducers: Drugs that induce (increase the activity of) CYP3A4 can lead to faster metabolism and lower blood levels of tolterodine, potentially reducing its effectiveness. Examples of strong CYP3A4 inducers include:
o Rifampin
o Phenytoin
o Carbamazepine
o St. John's Wort

Alternative treatments or dosage adjustments of Detrol might be considered when used with strong CYP3A4 inducers.

Other potential interactions:

Other anticholinergic drugs: Detrol has anticholinergic effects. Using it with other medications that also have anticholinergic properties (e.g., some antihistamines, tricyclic antidepressants, certain antipsychotics) can increase the risk of anticholinergic side effects such as dry mouth, constipation, blurred vision, and confusion. Caution is advised.

Cholinergic agonists: Detrol can antagonize the effects of cholinergic agonists (drugs that stimulate cholinergic receptors), potentially making them less effective.

Pregnancy or Breastfeeding:

There are no adequate and well controlled studies in pregnant women. Detrol should be used during pregnancy only if clearly needed. Caution should be exercised when Detrol is administered to a nursing woman. It is unknown whether Detrol is excreted in human milk. Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Frequently Asked Questions about Detrol at Canada Pharmacy Online:

Why is Detrol more affordable in Canada than in the United States?

Prescription drug prices, including Detrol, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Detrol tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Detrol at one time, as per your doctor’s prescription.

Can I buy Detrol over the counter from you?

No, Detrol requires a prescription from your doctor. We are unable to sell this product without a valid prescription from your doctor.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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