Diprolene (Betamethasone Dipropionate)

Name: Diprolene
Brand: Schering
SKU: 5623
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Diprolene Ointment

Manufacturer: Schering

Country: Canada

Dosage: 0.05 %/50 gm

Qty-Price (USD):

Generic Equivalent of Diprolene

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Betamethasone Dipropionate Cream

Manufacturer: Generic

Country: Canada

Dosage: 0.05 %/50 gm

Qty-Price (USD):

Type:

Product: Betamethasone Dipropionate Lotion

Manufacturer: Generic

Country: Canada

Dosage: 0.05 %/60 ml

Qty-Price (USD):

Type:

Product: Betamethasone Dipropionate Ointment (ON BACKORDER)

Manufacturer: Generic

Country: Canada

Dosage: 0.05 %/50 gm

Qty-Price (USD):

Diprolene Information

medically reviewed by Carol Hou (BSc. Pharm) on June 18, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Diprolene and Betamethasone Dipropionate at CanadaPharmacyOnline.com

Brand Diprolene, manufactured and marketed by Organon, is available in Canada. (Organon was formerly part of Merck, which had acquired Schering-Plough)

Generic betamethasone dipropionate is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important information about Generic Betamethasone Dipropionate:

Generic betamethasone dipropionate contains the same active ingredient as the brand-name Diprolene, and meets the same effectiveness, safety, and quality standards. This means it is designed to work in the same way as Diprolene. While specific bioequivalence studies are conducted to ensure generic medications have comparable absorption rates and overall effects, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about generic betamethasone dipropionate.

For information about generic drug approval and bioequivalence, please visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand Diprolene is commonly available in the strength of 0.05 %/50 gm ointment.

Generic betamethasone dipropionate is available in various strengths and forms:
• 0.05 %/50 gm cream
• 0.05 %/50 ointment
• 0.05 %/60 ml lotion

For Diprolene (augmented betamethasone dipropionate), a super-high potency topical corticosteroid, the maximum recommended dose is typically not to exceed 50 grams per week.

Your doctor will determine the appropriate dose based on your needs and medical condition.

Usage:

Diprolene (betamethasone dipropionate) is a very strong prescription medication used to treat severe inflammatory skin conditions like certain types of eczema, psoriasis, and dermatitis. It helps reduce the redness, swelling, and itching associated with these conditions. For more information, please refer to the product labeling information: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/018741s040lbl.pdf.

Mechanism of Action:
Diprolene is a topical, super high-potency corticosteroid used to treat skin conditions characterized by inflammation or itching. It works by calming down your skin's overactive response that causes inflammation. Diprolene works by calming down your skin's overactive response that causes inflammation. When you apply it, the medicine gets into your skin cells and acts like a "switch" to turn off the production of chemicals that cause redness, swelling, and itching. It also helps to narrow tiny blood vessels in the treated area, which further reduces inflammation.

Use Diprolene exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor. Follow the instructions on the Organon website: https://www.organon.com/product/usa/pi_circulars/d/diprolene/diprolene_ointment_ppi.pdf. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before using Diprolene, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Diprolene, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Diprolene, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Acne-like eruptions
• Adrenal gland problems (HPA axis suppression): The body's natural production of steroids can be suppressed, leading to fatigue, weakness, weight loss, or dizziness.
• Blistering
• Cushing's syndrome: A condition caused by too much cortisol in the body, leading to symptoms like weight gain (especially in the face and trunk), high blood pressure, and muscle weakness.
• Growth and weight effects in children: Long-term use in children can potentially slow growth or affect weight gain.
• High blood sugar (Hyperglycemia): Especially relevant for individuals with diabetes.
• Inflamed hair follicles (Folliculitis)
• Redness of the skin (Erythema)
• Skin irritation: Burning, stinging, itching, or dryness at the treated area. These often improve as your skin adjusts to the medication.
• Vision problems include an increased risk of developing cataracts or glaucoma (increased pressure in the eye), particularly if the medication is used near the eyes or for a very long time. Report any blurred vision, eye pain, or other vision changes to your doctor immediately.

Serious or rare side effects: Stop Diprolene and seek immediate medical attention if you experience any of the following:
• Allergic contact dermatitis: A rash or worsening of the treated condition due to an allergic reaction to the medication itself or its ingredients.
• Changes in skin color: This can include lightening (hypopigmentation) or darkening (hyperpigmentation) of the skin.
• Easy bruising or skin tearing
• Increased hair growth (Hypertrichosis) in the treated area.
• Perioral dermatitis: A rash around the mouth.
• Rosacea: Worsening or development of rosacea, characterized by redness and bumps on the face.
• Skin infections: Topical corticosteroids can sometimes worsen existing skin infections or make new ones more likely if the skin barrier is compromised.
• Skin thinning (Atrophy): This is one of the most common and significant concerns with strong topical steroids. It can make the skin appear shiny, wrinkled, or translucent, and underlying veins may become more visible.
• Stretch marks (Striae): These can be permanent, especially in areas where skin folds (like the groin or armpits).
• Telangiectasias: Enlarged or visible blood vessels ("spider veins").

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Diprolene.

Diprolene should not be used if:
• Bacterial infections: If an active bacterial infection is present, it should be treated with an antibiotic first.
• Broken, Wounded, or Severely Damaged Skin: Increased absorption and side effects are a risk.
• Eyes or Eyelids (Ophthalmic Use): Diprolene is not formulated for eye use and contact can lead to serious eye problems like cataracts or glaucoma.
• Face: Due to the risk of severe skin thinning, rosacea-like eruptions, and perioral dermatitis.
• Fungal infections: Like athlete's foot, ringworm, or candidiasis, unless an appropriate antifungal treatment is being used concurrently.
• Groin and Armpits (Axillae): These areas are prone to increased absorption and side effects due to skin folds and moisture.
• Hypersensitivity/Allergy: If a patient has a known allergy or hypersensitivity to betamethasone dipropionate, other corticosteroids, or any other ingredient in the Diprolene formulation, they should not use it.
• Perioral Dermatitis and Rosacea: Diprolene and other potent topical corticosteroids are typically contraindicated in these conditions, as they can worsen them.
• Pre-existing Skin Atrophy: If the skin at the treatment site is already thinned or damaged, Diprolene should be avoided.
• Skin Infections (untreated): Diprolene should generally not be used on skin areas that have untreated viral, fungal, or bacterial infections. This includes:
• The risk of HPA axis suppression.
• Tuberculosis of the skin.
• Use on Certain Body Areas (generally avoided): While not strict contraindications for all cases, Diprolene is generally not recommended for use on the specific body areas.
• Viral infections: Such as herpes simplex (cold sores, fever blisters), vaccinia (cowpox), or varicella (chickenpox, shingles). Corticosteroids can suppress the immune response and potentially worsen these infections.

Drug Interactions:

Before taking Diprolene, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Mayo Clinic: https://www.mayoclinic.org/drugs-supplements/betamethasone-dipropionate-topical-application-route/description/drg-20073667.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Diprolene may interact with other medicines, including but not limited to:

• Conditions that increase absorption: While rare, if Diprolene is used on very large areas of your skin, for a long time, under bandages or wraps, or on skin that is broken or very damaged, more of the medicine could get into your bloodstream. If this happens, it could potentially affect conditions like:
o Diabetes: It might make blood sugar harder to control.
o Immune system problems: It could slightly increase the risk of infection.
o Other medications: In very rare cases, it could affect how certain other medications work, especially those that are sensitive to steroids.
• Using other steroid creams: If you're using other steroid creams or ointments (even weaker ones) at the same time as Diprolene, or if you're taking steroid medications by mouth, there's a slightly higher chance that too much steroid could be absorbed into your body. This could lead to more side effects. Always tell your doctor if you're using multiple steroid products.

Pregnancy and Breastfeeding:

If you are pregnant, planning to become pregnant, or breastfeeding, it's crucial to talk with your doctor before using Diprolene. While Diprolene is a cream or ointment applied to the skin, and generally, only a small amount enters your bloodstream, higher amounts could be absorbed if used in large areas, for long periods, or under bandages. Animal studies with similar medications have shown potential risks to an unborn baby, so your doctor will carefully weigh whether the benefits of treating your skin condition outweigh any potential risks to the pregnancy. If you are breastfeeding, it is not fully known how much Diprolene might pass into breast milk.

Use in Children:

Diprolene is generally not recommended for children under 13 years of age. If too much Diprolene is absorbed, it can lead to serious side effects that affect a child's entire body, such as issues with their growth, weight, or even their body's natural hormone production. Always consult your child's eye doctor for the most appropriate and safest treatment for their eye condition.

Frequently Asked Questions about Diprolene at CanadaPharmacyOnline.com:

Why is Diprolene more affordable in Canada than in the United States?

Prescription drug prices, including Diprolene, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I buy over the counter from you?

No, Diprolene requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Diprolene I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Diprolene at one time, as per your doctor's prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Diprolene?

Yes, there is a generic alternative for this product called Betamethasone Dipropionate.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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