Effient (Prasugrel)

Name: Effient
Brand: Daiichi Sankyo
SKU: 6652
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Effient

Manufacturer: Daiichi Sankyo

Country: United Kingdom

Dosage: 5 mg

Qty-Price (USD):

Type:

Product: Effient

Manufacturer: Eli Lilly

Country: Turkey

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Effient

Manufacturer: Eli Lilly

Country: United Kingdom

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Effient (ON BACKORDER)

Manufacturer: Eli Lilly

Country: Turkey

Dosage: 10 mg

Qty-Price (USD):

Generic Equivalent of Effient

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Prasugrel

Manufacturer: Generic

Country: India

Dosage: 5 mg

Qty-Price (USD):

Type:

Product: Prasugrel

Manufacturer: Generic

Country: Canada

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Prasugrel

Manufacturer: Generic

Country: India

Dosage: 10 mg

Qty-Price (USD):

Effient Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on August 13, 2025.

Prasugrel at CanadaPharmacyOnline.com

Prasugrel is available globally under the brand name of Effient. In Turkey, it is distributed and marketed by Eli Lilly. In the United Kingdom, it is distributed by Daiichi Sankyo.

Generic prasugrel is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Effient:

Generic prasugrel contains the same active ingredient as the brand-name Effient and is required to meet the same safety, effectiveness, and quality standards as the brand-name product. This means it's designed to work in the same way as prasugrel, also known as Effient. Studies have demonstrated bioequivalence between generic and brand-name prasugrel, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic prasugrel, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage

Effient and generic prasugrel are available as oral tablets in doses of 5 mg and 10 mg.

Your doctor will determine the appropriate dose based on your individual needs and medical history.

Usage

Effient (prasugrel) is a prescription medication used to reduce the rate of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be managed with percutaneous coronary intervention (PCI). This includes patients with:
• Non-ST Segment Elevation Myocardial Infarction (NSTEMI)
• ST Segment Elevation Myocardial Infarction (STEMI)
• Unstable Angina (UA)

Mechanism of Action
Effient (prasugrel) is an antiplatelet medication that belongs to the thienopyridine class. It is a prodrug that is rapidly converted in the body to an active metabolite. This active metabolite irreversibly binds to the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. By blocking this receptor, prasugrel inhibits ADP-mediated platelet activation and aggregation, thereby reducing the formation of dangerous blood clots. The irreversible binding means that the antiplatelet effect lasts for the lifetime of the platelets (about 7-10 days), as new platelets must be produced for normal platelet function to resume. This action helps to prevent thrombotic events such as heart attack and stroke in at-risk patients.

Take Effient exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Effient, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Effient, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common Side Effects - The following are some common side effects of Effient; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Anemia (low red blood cells)
• Back pain
• Bradycardia (slow heart rate)
• Chest pain (non-cardiac)
• Cough
• Diarrhea
• Dizziness
• Dyspnea (shortness of breath)
• Fatigue
• Headache
• Hypertension (high blood pressure)
• Hypotension (low blood pressure)
• Nausea
• Pain in the extremity
• Peripheral edema (swelling of hands/feet)
• Pyrexia (fever)
• Rash

Serious Side Effects - These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Bleeding: Prasugrel significantly increases the risk of bleeding, which can be severe, life-threatening, or even fatal. This includes spontaneous bleeding (e.g., gastrointestinal, intracranial) or bleeding related to medical procedures. Signs may include:
o Unusual bruising or easy bruising
o Nosebleeds that are frequent or difficult to stop
o Bleeding gums
o Blood in urine (pink, red, or dark brown)
o Blood in stools (black, tarry, or bright red)
o Vomiting blood or material that looks like coffee grounds
o Severe or uncontrolled bleeding from cuts
o Any signs of internal bleeding (e.g., severe headache, vision changes, weakness on one side of the body, confusion, slurred speech).
• Hypersensitivity Reactions: Including angioedema (swelling of the face, lips, tongue, or throat, which may cause difficulty breathing or swallowing) or anaphylaxis (a severe allergic reaction characterized by widespread hives, difficulty breathing, wheezing, dizziness, or fainting).
• Thrombotic Thrombocytopenic Purpura (TTP): A rare but severe blood disorder that can lead to blood clots throughout the body. Symptoms may include:
o Fever
o Unusual weakness or extreme paleness
o Small red or purple spots on the skin (petechiae or purpura)
o Yellowing of the skin or eyes (jaundice)
o Confusion or changes in mental status
o Seizures
o Rapid heart rate, shortness of breath.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Effient, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Effient should not be used if:
• You have active pathological bleeding (e.g., peptic ulcer, intracranial hemorrhage).
• You have a history of transient ischemic attack (TIA) or stroke.
• You are allergic to prasugrel or any other ingredient in Effient.
• You are likely to undergo urgent coronary artery bypass graft (CABG) surgery.

Tell your doctor about all of your medical conditions, past and present, before starting Effient. This is crucial because certain conditions affect whether Effient is right for you. These conditions may include, but are not limited to:
• Any active bleeding (e.g., stomach ulcer, bleeding in the brain, recent major trauma or surgery)
• History of stroke or transient ischemic attack (TIA)
• Kidney disease (caution with end-stage renal disease)
• Liver disease (caution with severe hepatic impairment, Child-Pugh class C)
• Low body weight (<60 kg), as this may increase bleeding risk
• Propensity to bleed (e.g., recent trauma, recent surgery, recent or recurrent gastrointestinal bleeding, active peptic ulcer disease, bleeding disorders)
• Scheduled surgery or dental procedure

Drug Interactions

Before taking Effient, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the Effient prescribing information | Eli Lilly.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Effient. Effient may interact with other medicines, but is not limited to:
• Anticoagulants (e.g., warfarin, heparin, dabigatran, rivaroxaban): Concomitant use significantly increases the risk of bleeding. Close monitoring is required.
• Aspirin: Effient is intended to be used with aspirin; however, the risk of bleeding is increased compared to aspirin alone.
• Non-steroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen): Chronic concomitant use increases the risk of bleeding.
• Opioids: May reduce the absorption and exposure to the active metabolite of prasugrel, potentially leading to reduced antiplatelet effect.
• Other P2Y12 inhibitors (e.g., clopidogrel, ticagrelor): Concomitant use with other P2Y12 inhibitors is generally not recommended and can significantly increase bleeding risk.
• St. John's Wort and other herbal supplements known to affect bleeding/clotting (e.g., ginger, ginkgo biloba, horse chestnut seed): May increase bleeding risk.

Pregnancy and Breastfeeding

Effient should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Animal studies have shown some evidence of effects on the fetus. However, human data are limited, and due to the mechanism of action (antiplatelet effect and associated bleeding risk), the benefits and risks of therapy and possible risks to the fetus should be carefully considered.

No published information is available on the use of prasugrel during breastfeeding. It is unknown if prasugrel is excreted in human milk. Caution should be exercised when Effient is administered to a nursing mother, and the infant should be monitored for signs of bleeding or bruising. Consult your doctor for personalized advice.

Use in the Elderly

Effient is generally not recommended for use in patients 75 years of age or older due to an increased risk of fatal and intracranial bleeding and uncertain benefit, except in high-risk situations (e.g., patients with diabetes or a history of prior myocardial infarction) where the benefit may outweigh the risk. If used, caution and close monitoring for bleeding are advised.

Use in Children

Effient is not recommended for use in children (patients under 18 years of age) due to a lack of data on safety and efficacy in this population.

Frequently Asked Questions about Effient at Canada Pharmacy Online:

Why is Effient more affordable in Canada than in the United States?

Prescription drug prices, including Effient, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Effient at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Effient requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to take Effient?

Effient can be taken with or without food. It is usually taken once daily. Your doctor will provide specific instructions regarding the timing of your loading dose and maintenance dose after your PCI procedure. Swallow the tablet whole and do not crush, chew, or break it.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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