Kerendia (Finerenone)

Name: Kerendia
Brand: Bayer
SKU: 7741
Availability: InStock

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Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Kerendia Tablet

Manufacturer: Bayer

Country: Canada

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Kerendia Tablet

Manufacturer: Bayer

Country: India

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Kerendia Tablet

Manufacturer: Bayer

Country: United Kingdom

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Kerendia Tablet

Manufacturer: Bayer

Country: Canada

Dosage: 20 mg

Qty-Price (USD):

Type:

Product: Kerendia Tablet

Manufacturer: Bayer

Country: India

Dosage: 20 mg

Qty-Price (USD):

Type:

Product: Kerendia Tablet

Manufacturer: Bayer

Country: Australia

Dosage: 20 mg

Qty-Price (USD):

Type:

Product: Kerendia Tablet (ON BACKORDER)

Manufacturer: Bayer

Country: United Kingdom

Dosage: 20 mg

Qty-Price (USD):

Generic Equivalent of Kerendia

Type

Product

Manufacturer

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Qty-Price (USD)

There is no generic product of Kerendia.

Kerendia Information

medically reviewed by Carol Hou (BSc. Pharm) on December 5, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Kerendia and Finerenone at CanadaPharmacyOnline.com

The brand Kerendia (finerenone) is marketed and manufactured by Bayer. It is available in Canada, the United Kingdom (UK), and other countries.

Generic finerenone is currently unavailable (at this pharmacy).

Dosage:

The brand-name Kerendia is available as an oral tablet in the following strengths:
• 10 mg
• 20 mg

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Kerendia (finerenone) is a targeted prescription medication primarily used for adults with chronic kidney disease (CKD) related to type 2 diabetes. Its primary purpose is to reduce the risk of serious long-term outcomes, including slowing the progression to end-stage kidney disease (ESKD), preventing cardiovascular issues such as heart attacks or hospitalization for heart failure, and lowering the risk of cardiovascular death. It is also approved to lower cardiovascular risks in adults with heart failure (LVEF ≥ 40%).

Mechanism of Action:
Kerendia (finerenone) is a non-steroidal Mineralocorticoid Receptor Antagonist (nsMRA) that blocks the Mineralocorticoid Receptor (MR), which is often overactive in patients with chronic kidney disease and heart failure. This overactivation of the MR triggers harmful pathways that lead to inflammation and the development of scar tissue (fibrosis) in the heart and kidneys. By binding to and blocking the MR, finerenone disrupts these damaging processes, helping to reduce inflammation and scarring, and ultimately slowing the progression of kidney disease while lowering the risk of related cardiovascular issues.

Take Kerendia exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult a doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Kerendia, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Kerendia (finerenone). It is not an exhaustive list, and individual reactions can vary.

Common side effects – These are common side effects of Kerendia, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Decreased Estimated Glomerular Filtration Rate (eGFR) (an initial, slight decline in kidney function that typically stabilizes)
• Hypotension (low blood pressure, which can cause dizziness or light-headedness)

Other Potential Side Effects (less common):
• Anemia (low red blood cell count)
• Hyperuricemia (increased uric acid levels in the blood)
• Hyperkalemia (high potassium level in the blood)
• Hyponatremia (low sodium level in the blood)
• Pruritus (itching)

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms.
• Severe Allergic Reaction: Although rare, a severe reaction (like Angioedema) requires immediate medical attention and may present as swelling of the face, lips, tongue, or throat, or difficulty breathing.
• Severe Hyperkalemia: While most cases of hyperkalemia are mild or moderate, dangerously high levels can cause: o Confusion
o Irregular heartbeat (arrhythmia)
o Muscle weakness
o Nausea or vomiting
o Shortness of breath
o Tingling or numbness in the extremities

Contraindications:

The following are key contraindications and important warnings (not an exhaustive list). Before starting Kerendia, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Kerendia (finerenone) if you have the following conditions:
• Hypersensitivity: A known allergy or hypersensitivity to finerenone or any of the inactive ingredients.
• Severely Reduced Kidney Function OR High Serum Potassium: You have an Estimated Glomerular Filtration Rate (eGFR) less than 15 mL/min/1.73 m2 (a measure of severe kidney impairment), OR you have a baseline serum potassium concentration greater than 5.0 mEq/L.
• You are currently taking:
o Strong CYP3A4 Inhibitors: E.g., itraconazole, ketoconazole, ritonavir, clarithromycin, cobicistat. This is contraindicated because these drugs drastically increase the level of finerenone in your body, which raises the risk of dangerously high potassium levels and hypotension (low blood pressure).
o Potassium-Sparing Diuretics: Such as spironolactone, eplerenone, amiloride, or triamterene. The co-administration of these drugs is contraindicated because it significantly increases the risk of severe hyperkalemia (high potassium).

Note on Adrenal Insufficiency: While Adrenal Insufficiency warrants caution and monitoring due to the risk of hyperkalemia, it is not a formal contraindication to Kerendia.

Tell your doctor about all of your medical conditions, past and present, before starting Kerendia. This is crucial as certain conditions affect the drug’s safety.
• Kidney Function and Potassium Levels: Severe kidney impairment (eGFR less than 15 mL/min/1.73 m2) or a baseline serum potassium level (greater than 5.0 mEq/L), as Kerendia is contraindicated in these situations.
• Liver Problems: Severe hepatic impairment (Child-Pugh Class C), as Kerendia should not be initiated due to the expected significant increase in drug exposure.

Drug Interactions:

Before taking Kerendia, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the patient’s medication information at https://www.bayer.com/sites/default/files/kerendia-pm-en.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Kerendia. Kerendia may interact with other medicines, but is not limited to:

Significant Interactions (Avoid or Contraindicated)
• Strong CYP3A4 Inhibitors: These medications and substances significantly increase finerenone levels in your blood, raising the risk of severe hyperkalemia (high potassium) and hypotension. This combination is an absolute contraindication.
o Examples include: antifungal drugs (such as Itraconazole, Ketoconazole), certain antibiotics (such as Clarithromycin), and some antiviral drugs (such as Ritonavir or Cobicistat).
• Grapefruit or Grapefruit Juice acts as a potent inhibitor and must also be avoided.
• Potassium-Sparing Diuretics: These diuretics are specifically designed to retain potassium. When taken with Kerendia, they produce an additive effect that significantly raises the risk of severe hyperkalemia.
o Examples include: Spironolactone, Eplerenone, Triamterene, and Amiloride.
• Strong CYP3A4 Inducers: These medications cause your liver to break down finerenone too quickly, leading to significantly lower drug levels in your blood and resulting in a Loss of Efficacy. This combination is also an absolute contraindication.
o Examples include: certain seizure medications (like Phenytoin, Carbamazepine), and the herbal supplement St. John's Wort.

Moderate Interactions (Dose Adjustment and Close Monitoring Required)
• Moderate or weak CYP3A4 inhibitors: These medications cause a slight increase in finerenone levels, which could raise the risk of Kerendia's side effects, including hyperkalemia.
o Examples include: ACE inhibitors (e.g., Lisinopril, Ramipril), ARBs (e.g., Losartan, Valsartan), potassium supplements, and salt substitutes containing potassium chloride.
• Nonsteroidal Anti-inflammatory Drugs (NSAIDs): NSAIDs can independently affect kidney function and increase potassium levels, which can lead to an increased risk of hyperkalemia and worsening kidney function. Potassium and kidney function monitoring is advised.
o Examples include: ibuprofen, naproxen, and meloxicam.
• Other Drugs Increasing Potassium: Any drug that already has a known effect of raising potassium levels can have an additive effect when combined with Kerendia, increasing the risk of Hyperkalemia. Close monitoring is required.
o Examples include: ACE inhibitors (e.g., Lisinopril, Ramipril), ARBs (e.g., Losartan, Valsartan), potassium supplements, salt substitutes containing potassium chloride, and the antibiotic Trimethoprim/Sulfamethoxazole.

Pregnancy and Breastfeeding:

Kerendia (finerenone) is generally not recommended during pregnancy because there is no available human data to confirm its safety, and animal studies suggest a risk of developmental harm to the fetus. Therefore, women of childbearing potential should use effective contraception while taking it. Similarly, due to the unknown risk of the drug passing into breast milk and potentially causing serious side effects in a nursing infant, women are advised to avoid breastfeeding while on Kerendia and for 1 day after the final dose.

Any decision regarding the use of Kerendia during pregnancy or breastfeeding should involve careful consultation with a healthcare provider to assess the necessity of the medication against the potential risks.

Use in Children:

Kerendia (finerenone) is not approved for use in children or pediatric patients (individuals under 18 years old). This is because the safety and effectiveness of the medication have not been established in this age group, as clinical trials were conducted only in adults. Therefore, if a child needs treatment for conditions like chronic kidney disease related to type 2 diabetes, a specialist should be consulted to determine suitable, approved pediatric therapies.

Frequently Asked Questions about Kerendia at CanadaPharmacyOnline:

Why is Kerenida more affordable in Canada than in the United States?

Prescription drug prices, including Kerendia, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Kerendia I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Kerendia at one time, as per your doctor's prescription.

Can I buy Kerendia from you over the counter?

No, Kerendia requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Kerendia?

No, there is no generic available for this product.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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