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Mezera (Mesalazine - also known as Mesalamine)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Mezera 80 gm Foam (14 Actuations)
Manufacturer: Avir Pharma
Country: Canada
Dosage: 1 gm / Actuation
Qty-Price (USD):
Type: drug type
Product: Mezera Tablet
Manufacturer: Avir Pharma
Country: Canada
Dosage: 500 mg
Qty-Price (USD):

Generic Equivalent of Mezera
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no generic product of Mezera.

Mezera Information

Mezera at CanadaPharmacyOnline.com

The manufacturer of the brand-name Mezera is Avir Pharma Inc. In Canada, it is a prominent choice for patients who require targeted mesalamine delivery.

The generic mesalazine is currently unavailable (at this pharmacy).

Dosage:

Mezera is available in several specialized forms to ensure the medicine reaches the site of inflammation:
• Rectal foam enema: 1gm/ actuation
• Tablet: 500 mg oral tablet

The dosage depends on the severity of the condition and the form used.

Usage:

Mezera is used to treat and manage ulcerative colitis, specifically to induce remission in mild- to-moderate cases. It is also used to treat proctitis (inflammation of the rectum) and sigmoiditis (inflammation of the lower colon). By delivering medication directly to the affected area, Mezera helps reduce symptoms such as rectal bleeding, abdominal pain, and frequent diarrhea.

Mechanism of Action
Mesalazine, the active ingredient in Mezera, works as a localized anti-inflammatory "coating" for the intestines. Mesalazine, also known as mesalamine, belongs to a class of medications known as 5-aminosalicylates (5-ASA). Unlike most pills that work through the bloodstream, mesalamine works by coming into direct contact with the inflamed lining of the bowel. It stops the production of certain natural chemicals (prostaglandins) that the body produces in response to injury or disease. These chemicals are responsible for the swelling, pain, and tissue damage seen in ulcerative colitis. By neutralizing these inflammatory triggers, the medication allows the bowel lining to heal. It prevents future "flare-ups" of the disease.

Use Mezera exactly as your doctor prescribes, according to the product monograph. For rectal forms, it is best to empty your bowels before use and apply the medication at bedtime to allow it to remain in place overnight. Tablets should be swallowed whole; do not crush or chew them.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Mezera, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Mezera (mesalazine). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Mezera; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abdominal pain or gas
• Dizziness
• Headache
• Nausea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Chest Pain: Rare cases of heart muscle inflammation (myocarditis) have been reported.
• Kidney Problems: Signs such as changes in urine amount, swelling in the feet, or unusual tiredness.
• Liver Issues: Yellowing of the eyes/skin or persistent dark urine.
• Worsening Colitis: Increased stomach pain, cramping, or bloody diarrhea.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Mezera, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Mezera/mesalazine if:
• Allergies: You have a known hypersensitivity to mesalazine, aspirin, or other salicylates
• Severe Kidney or Liver Disease: This medication may worsen existing organ impairment.

Tell your doctor about all of your medical conditions, past and present, before starting Mezera. This is crucial as certain conditions affect the drug's safety.
• Gastric Ulcers: Use with caution if you have an active stomach or intestinal ulcer.

Drug Interactions:

Before taking Mezera, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the patient medication information at https://www.avirpharma.com/pdf/Mezera-Tab-Patient-Information.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Mezera. Mezera may interact with other medicines, including but not limited to:
• Azathioprine or 6-Mercaptopurine: Mezera may increase the risk of blood disorders when taken with these specific immunosuppressing drugs.
• Nephrotoxic Agents: Using Mezera with other drugs that stress the kidneys (like certain NSAIDs or antivirals) can increase the risk of kidney damage.

Pregnancy and Breastfeeding:

Mezera is generally considered safe during pregnancy when the benefits outweigh the risks. However, you should use it only under your doctor's guidance. Mesalamine passes into breast milk in small amounts. While generally considered safe, some infants may develop diarrhea. Monitor your baby closely and consult your doctor.

Use in Children:

The safety and effectiveness of Mezera in children under 18 years of age have not been fully established. Use in pediatric patients is typically at the discretion of a specialist.

Frequently Asked Questions about Mezera at Canada Pharmacy Online

Why is Mezera more affordable in Canada than in the United States?

Prescription drug prices, including Mezera, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Mezera I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Mezera per prescription from your doctor.

Can I buy Mezera from you over the counter?

No, Mezera requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Mezera?

No, the generic alternative is currently unavailable (at this pharmacy).

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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