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Home > Anti-coagulant > Pradaxa or Equivalent

Pradaxa (Dabigatran Etexilate)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Pradaxa Capsule
Manufacturer: Boehringer Ingelheim
Country: Canada
Dosage: 75 mg
Qty-Price (USD):
Type: drug type
Product: Pradaxa Capsule
Manufacturer: Boehringer Ingelheim
Country: Canada
Dosage: 110 mg
Qty-Price (USD):
Type: drug type
Product: Pradaxa Capsule
Manufacturer: Boehringer Ingelheim
Country: Canada
Dosage: 150 mg
Qty-Price (USD):
Type: drug type
Product: Pradaxa Capsule
Manufacturer: Boehringer Ingelheim
Country: New Zealand
Dosage: 150 mg
Qty-Price (USD):
Generic Equivalent of Pradaxa
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Dabigatran Etexilate Capsule
Manufacturer: Generic
Country: Canada
Dosage: 75 mg
Qty-Price (USD):
Type: drug type
Product: Dabigatran Etexilate Capsule
Manufacturer: Generic
Country: India
Dosage: 75 mg
Qty-Price (USD):
Type: drug type
Product: Dabigatran Etexilate Capsule
Manufacturer: Generic
Country: Canada
Dosage: 110 mg
Qty-Price (USD):
Type: drug type
Product: Dabigatran Etexilate Capsule
Manufacturer: Generic
Country: India
Dosage: 110 mg
Qty-Price (USD):
Type: drug type
Product: Dabigatran Etexilate Capsule
Manufacturer: Generic
Country: Canada
Dosage: 150 mg
Qty-Price (USD):
Type: drug type
Product: Dabigatran Etexilate Capsule
Manufacturer: Generic
Country: India
Dosage: 150 mg
Qty-Price (USD):
Pradaxa online Canadian Pharmacy

Pradaxa Information

portrait medically reviewed by Carol Hou (BSc. Pharm) on September 8, 2025.
A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Pradaxa and Dabigatran Etexilate at CanadaPharmacyOnline.com

The brand name Pradaxa, manufactured by Boehringer Ingelheim, is available in many countries worldwide, including Canada and New Zealand.

Generic dabigatran etexilate is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Dabigatran etexilate:

Generic dabigatran etexilate contains the same active ingredient as brand-name Pradaxa and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Pradaxa. Studies have shown that generic dabigatran etexilate is bioequivalent to brand-name Pradaxa, meaning they have similar absorption rates and reach similar concentrations in the bloodstream. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts.

Dosage:

The brand Pradaxa and generic dabigatran etexilate are commonly available in 75 mg, 110 mg, and 150 mg oral capsules.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Pradaxa (dabigatran etexilate) is an anticoagulant medication primarily used to prevent and treat blood clots. Its main indications include reducing the risk of stroke and systemic embolism in adults with non-valvular atrial fibrillation. Additionally, it is prescribed for the treatment and reduction of recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE) in pediatric patients aged >3 months to less than 18 years who have completed at least 5 days of initial parenteral anticoagulant therapy. For pediatric patients aged 8 to less than 18 years, Pradaxa is available as oral capsules for those who can swallow them whole for DVT/PE treatment and recurrence reduction. An oral pellet formulation is available for the same indications for younger pediatric patients (>3 months to less than 8 years). Pradaxa also helps reduce the risk of recurrent DVT and PE, and it is utilized for preventing DVT and PE in adults following hip replacement surgery.

Mechanism of Action:
Pradaxa (dabigatran etexilate) is an anticoagulant that is a direct thrombin inhibitor. Administered as an inactive prodrug, it is converted in the body to its active form, dabigatran. Dabigatran directly and reversibly binds to and inhibits thrombin (Factor IIa), a key enzyme in the blood clotting cascade. This action prevents thrombin from converting fibrinogen into fibrin, the essential component of blood clots, and also inhibits thrombin-induced platelet aggregation. Dabigatran's ability to inactivate free and clot-bound thrombin helps prevent clot formation and growth, making it effective for preventing stroke in atrial fibrillation and treating/preventing deep vein thrombosis and pulmonary embolism.

Take Pradaxa exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Pradaxa, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Pradaxa (dabigatran etexilate). It is not an exhaustive list, and individual reactions can vary.

Common side effects - These are some common side effects of Pradaxa, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Gastrointestinal (GI) issues: Symptoms include diarrhea, upset stomach, stomach ache, heartburn, nausea, and vomiting.
• Mild bleeding: Symptoms include bleeding gums, bruising more easily than usual, heavier than normal menstrual bleeding, nosebleeds, and minor cuts bleeding for a bit longer.

Other Potential Side Effects (less common):
• Hair loss
• Mouth ulcers

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions: Rash, itching, hives, swelling of the face, lips, or tongue, difficulty breathing.
• Blood clots in or around the spine: This is a serious but rare side effect that can occur if you have a spinal or epidural procedure while on Pradaxa, potentially leading to paralysis. Symptoms include back pain, tingling, numbness, leg weakness, or bladder/bowel control.
• Increased risk of blood clots when stopping Pradaxa: It's crucial not to stop taking Pradaxa without consulting your doctor, as premature discontinuation of any oral anticoagulant, including Pradaxa, significantly increases the risk of thrombotic events such as stroke or recurrent DVT/PE.
• Serious bleeding: Symptoms include bloody or black, tarry stools, red or dark brown urine, coughing up blood or vomit that looks like coffee grounds, bleeding that does not stop, unusual or severe headaches (may indicate bleeding in the brain), dizziness, weakness, or unusual tiredness (can be signs of internal bleeding or anemia)
• Unexpected pain, especially joint pain with swelling

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Pradaxa, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Pradaxa should not be used if you:
• Currently have abnormal bleeding.
• Have had a severe allergic reaction to any of the ingredients in Pradaxa.
• Have had or plan to have a mechanical prosthetic heart valve replacement (Pradaxa is contraindicated due to an increased risk of stroke, valve thrombosis, and major bleeding).
• Have severely reduced kidney function.
• Have certain bleeding disorders or conditions that increase your risk of severe bleeding (e.g., recent brain or spinal injury, active stomach ulcers, or triple-positive antiphospholipid syndrome).

Tell your doctor about all of your medical conditions, past and present, before starting Pradaxa. This is crucial because certain conditions affect whether Pradaxa is right for you. These conditions may include, but are not limited to:
• Risk of bleeding: Pradaxa increases the risk of bleeding in general. Factors that increase this risk include being 75 years or older, having kidney problems, a history of stomach ulcers or bleeding, or taking other medications that increase bleeding risk (e.g., aspirin, NSAIDs, other blood thinners).
• Spinal/Epidural Hematoma: There's a boxed warning about the risk of spinal or epidural hematomas in patients treated with Pradaxa who receive neuraxial anesthesia or undergo spinal puncture. These hematomas can lead to long-term or permanent paralysis. The risk is higher if you have spinal deformities, have had spinal surgery or repeated spinal punctures, or are taking other medications that affect bleeding.
• Triple-positive antiphospholipid syndrome (direct oral anticoagulants (DOACs), including Pradaxa, are contraindicated due to a significantly increased risk of recurrent thrombotic events compared to vitamin K antagonists (like warfarin).

Drug Interactions:

Before taking Pradaxa, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Pradaxa product monograph: https://www.boehringer-ingelheim.com/ca/pdf/pradaxa-product-monograph.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also important to inform your doctor about any herbal supplements (e.g., St. John's wort, ginger), recreational drugs, or significant dietary changes you are making, as these could potentially interact with Pradaxa. Pradaxa may interact with other medicines, but is not limited to:
• Antiplatelet drugs (e.g., aspirin, clopidogrel)
• Certain antifungals (e.g., ketoconazole, itraconazole)
• Certain antiarrhythmics (e.g., dronedarone, amiodarone, quinidine)
• Certain antibiotics (e.g., clarithromycin, erythromycin)
• Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
• Other anticoagulants (e.g., warfarin, apixaban)
• P-glycoprotein (P-gp) inhibitors (can increase Pradaxa levels)
• P-glycoprotein (P-gp) inducers (can decrease Pradaxa levels, e.g., rifampin, St. John's wort, carbamazepine, phenytoin) • SSRIs and SNRIs (can increase bleeding risk)

Alcohol
Heavy or binge drinking of alcohol should be avoided as it can increase the risk of bleeding and stomach ulcers.

Pregnancy and Breastfeeding

Pradaxa (dabigatran) is generally not recommended during pregnancy or breastfeeding. It is crucial to avoid Pradaxa if you are pregnant or planning to be, as it crosses the placenta and animal studies have shown evidence of embryofetal lethality. Due to limited human data, your doctor will assess the risks and benefits and may switch you to an alternative anticoagulant, such as heparin, during pregnancy. Dabigatran is excreted into animal milk, and while specific comprehensive human data are limited, it is generally considered prudent to assume some excretion into human milk. Therefore, breastfeeding is generally not recommended during treatment with Pradaxa due to the potential for harm to the nursing infant.

Frequently Asked Questions about Pradaxa at Canada Pharmacy Online:

Why is Pradaxa more affordable in Canada than in the United States?

Prescription drug prices, including Pradaxa, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/.

What is the difference between Pradaxa 110 mg and 150 mg?

The difference in dosage represents the different amounts of the same active ingredient (dabigatran etexilate) present in each capsule.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many capsules I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Pradaxa at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Pradaxa requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for Pradaxa?

Yes, there is a generic alternative for this product called dabigatran etexilate.

Will I need to carry an alert card?

Yes, you should always carry an anticoagulant alert card with you when taking Pradaxa. This is important so medical personnel know you are on a blood thinner if you have an accident.

Will I need to stop Pradaxa before surgery or dental treatment?

Due to the risk of bleeding, your doctor or dentist may advise you to temporarily stop Pradaxa a few days before any planned surgery, medical, or dental procedure. Always tell your healthcare providers you are taking Pradaxa and show them your anticoagulant alert card.

Can I crush Pradaxa capsules?

Pradaxa capsules should not be opened, chewed, or crushed, as this can significantly alter the absorption and increase drug exposure, leading to an increased risk of bleeding.

How should I store Pradaxa capsules?

Pradaxa capsules are very sensitive to moisture and should be stored in their original blister packaging or manufacturer's bottle and used within a specific timeframe after opening (e.g., 4 months for the bottle).

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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