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Pulmicort Nebuamp (Budesonide)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Pulmicort Nebuamp (20 x 2ml)
Manufacturer: AstraZeneca
Country: Canada
Dosage: 0.50 mg/2 ml
Qty-Price (USD):

Generic Equivalent of Pulmicort Nebuamp
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Budesonide (5 x 2ml)
Manufacturer: Generic
Country: India
Dosage: 0.5 mg/2 ml
Qty-Price (USD):
Type: drug type
Product: Budesonide (5 x 2 ml)
Manufacturer: Generic
Country: India
Dosage: 1 mg/2 ml
Qty-Price (USD):

Pulmicort Nebuamp online Canadian Pharmacy

Pulmicort Nebuamp Information

portrait medically reviewed by Dr. HaVy Ngo, Pharmacist on May 5, 2025.

PULMICORT NEBUAMP and Budesonide at CanadaPharmacyOnline.com

Brand PULMICORT NEBUAMP (budesonide) is manufactured by AstraZeneca and is available in many countries worldwide, including Canada.

Generic budesonide is sourced from manufacturers meeting applicable local regulatory standards. The specific manufacturer of dispensed medication may vary.

Important Information about Generic Budesonide:

Generic budesonide contains the same active ingredient as brand-name PULMICORT NEBUAMP and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as PULMICORT NEBUAMP. Studies have demonstrated bioequivalence between generic and brand-name budesonide, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist, if you have any questions about using generic budesonide.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand PULMICORT NEBUAMP and generic budesonide are commonly available in 0.50 mg/2 ml nebuamps. Generic budesonide is also available in 1 mg/2 ml unit-dose vials or nebu

lizer solutions (at this pharmacy). Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

PULMICORT NEBUAMP (budesonide) is a prescription medication indicated for the maintenance treatment of bronchial asthma to control underlying airway inflammation. It is a nebulizer suspension formulation that is often preferred for patients who have difficulty using metered-dose inhalers, such as young children or those with severe asthma, or other individuals for whom a nebulizer is a more suitable delivery method. Asthma is a chronic respiratory disease characterized by airway inflammation, bronchoconstriction (narrowing of the airways), and increased mucus production. As with all inhaled corticosteroids used for maintenance, PULMICORT NEBUAMP is not intended to provide immediate relief of acute asthma symptoms. For sudden asthma symptoms, a rescue inhaler should be used. (refer to the product information leaflet.)

Mechanism of Action:
PULMICORT NEBUAMP (budesonide) is a synthetic corticosteroid. Budesonide exerts its anti-inflammatory effects in the airways by binding to intracellular glucocorticoid receptors. This receptor activation leads to altered gene transcription, resulting in the decreased production and release of various pro-inflammatory mediators (such as cytokines, chemokines, and leukotrienes) and the inhibition of inflammatory cell activity. This mechanism helps to control asthma symptoms, improve lung function, and reduce the frequency of asthma attacks by suppressing the inflammatory response associated with the condition.

Take PULMICORT NEBUAMP exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking PULMICORT NEBUAMP, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with PULMICORT NEBUAMP (budesonide). It is not an exhaustive list, and individual reactions can vary. This information is for educational purposes and should not replace professional medical advice. Before starting PULMICORT NEBUAMP, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are some common side effects of PULMICORT NEBUAMP, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Bad taste in the mouth
• Cough
• Diarrhea
• Dry throat
• Ear infections (in children)
• Headache
• Hoarseness
• Nausea
• Oral thrush (fungal infection in the mouth or throat). Rinsing your mouth with water after each use can help prevent oral thrush.
• Runny or stuffy nose
• Sore throat
• Skin irritation on the face (if using a face mask with the nebulizer)
• Thirst
• Tiredness
• Throat irritation
• Viral infections (in children)

Less Common but Potentially Serious Side Effects -Seek immediate medical attention or call emergency services if you experience any of the following:
• An allergic reaction includes rash, itching, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing.
• Bone problems (decreased bone mineral density (osteoporosis) with long-term use).
• Eye problems (blurred vision, eye pain, increased pressure in the eye (glaucoma), cataracts). These are more likely with long-term use.
• Increased risk of infections (symptoms of infection such as fever, chills, persistent sore throat, or cough). Corticosteroids can weaken the immune system.
• Mental/mood changes (depression, nervousness, restlessness, anxiety, or changes in behavior).
• Paradoxical bronchospasm (sudden wheezing or difficulty breathing after using the medication). If this occurs, stop using PULMICORT NEBUAMP and use your rescue inhaler immediately.
• Slowed growth in children and teenagers (long-term use may affect growth rate). Your doctor should monitor your child's growth.
• Symptoms of adrenal insufficiency (unusual tiredness or weakness, dizziness, nausea, vomiting). This can occur with long-term use or when switching from oral corticosteroids.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting PULMICORT NEBUAMP, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

PULMICORT NEBUAMP should not be used if you: • Are allergic to budesonide or any of the other ingredients in PULMICORT NEBUAMP.
• Are having an asthma attack or have status asthmaticus (a severe asthma attack). PULMICORT NEBUAMP is not a rescue medication and will not provide immediate relief.
• Have moderate to severe bronchiectasis (a chronic lung problem with damaged bronchial tubes) unless specifically directed and closely monitored by your doctor, as caution is advised in such cases.
• Have active, untreated pulmonary tuberculosis (TB). A history of treated TB should be discussed with your doctor, as careful monitoring may be required.
• Have an active, untreated fungal, bacterial, or viral infection of the respiratory system. The use of PULMICORT NEBUAMP in such cases requires careful evaluation by your doctor, considering the potential for immunosuppression

Tell your doctor about all of your medical conditions, past and present, before starting PULMICORT NEBUAMP. This is crucial because certain conditions can affect whether PULMICORT NEBUAMP is right for you. These conditions may include, but are not limited to:
• Active Infections - PULMICORT NEBUAMP is a corticosteroid, which can weaken the immune system. It may make it harder for your body to fight off infections. It should generally not be used if you have an active, untreated infection (bacterial, fungal, or viral), including tuberculosis of the respiratory tract or herpes simplex virus infection of the eye.
• Acute Asthma Attacks – PULMICORT NEBUAMP is a maintenance medication used to prevent asthma symptoms and should not be used to treat sudden asthma attacks. For quick relief, you will need to use a separate "rescue" inhaler (like salbutamol or terbutaline).
• Adrenal Insufficiency - While inhaled corticosteroids are less likely to cause adrenal suppression than oral steroids, prolonged use at high doses can still affect the adrenal glands' ability to produce cortisol. Symptoms of adrenal insufficiency can include tiredness, weakness, nausea, vomiting, and low blood pressure.
• Chickenpox and Measles - These infections can be more serious in people using corticosteroids like budesonide. If you are exposed to chickenpox or measles and are not immune, inform your doctor immediately.
• Glaucoma and Cataracts - Long-term use of inhaled corticosteroids may increase the risk of developing or worsening glaucoma (increased pressure in the eye) and cataracts (clouding of the lens). If you have these conditions, your doctor will likely monitor your eyes regularly.
• Hyperadrenocorticism (Cushing's Syndrome)- This condition involves the body producing too much cortisol. Budesonide is a corticosteroid and could potentially exacerbate some symptoms or interfere with the management of Cushing's syndrome.
• Liver Problems - If you have liver problems like cirrhosis, your liver may not process budesonide effectively. This could lead to higher levels of the drug in your body and an increased risk of side effects. Your doctor may need to monitor you more closely or adjust your dosage.
• Ocular Herpes Simplex - As PULMICORT NEBUAMP can weaken the immune system, it might cause a flare-up of ocular herpes if you have a history of it. Your doctor may recommend an antiviral medication to prevent this.
• Osteoporosis - Long-term use of inhaled corticosteroids can reduce bone mineral density, potentially increasing the risk of osteoporosis (weak bones). Your doctor may monitor your bone health, especially if you have risk factors for osteoporosis.
• Systemic Corticosteroid Use - If you have recently taken or are currently taking oral corticosteroids (like prednisone), switching to inhaled budesonide can sometimes lead to symptoms of adrenal insufficiency. This is because your body's natural production of cortisol may be suppressed. Your doctor will need to manage this transition carefully, and you may need to resume oral steroids temporarily during times of stress, such as illness, surgery, or trauma.

Drug Interactions:

Before taking PULMICORT NEBUAMP, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Drug and Health Products Portal | Canada.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also important to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with PULMICORT NEBUAMP.
• Certain Antivirals (e.g., ritonavir-containing medications): These can inhibit the CYP3A4 enzyme in the liver, which is responsible for breaking down budesonide, potentially leading to increased levels of budesonide in the body and a higher risk of side effects.
• CYP3A4 Inducers (e.g., rifampin, phenytoin, carbamazepine, St. John's Wort): These drugs increase the activity of the CYP3A4 enzyme, which can lead to a faster breakdown of budesonide and potentially reduce its effectiveness.
• Desmopressin: Concomitant use may increase the risk of hyponatremia (low sodium levels).
• Diuretics (water pills): May increase the risk of hypokalemia (low potassium levels).
• Moderate CYP3A4 Inhibitors (e.g., diltiazem, verapamil, grapefruit juice): These can also increase budesonide levels, although usually to a lesser extent than strong inhibitors. Grapefruit juice can inhibit CYP3A4 in the gut lining.
• Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Aspirin: Long-term use with inhaled corticosteroids might increase the risk of stomach ulcers.

• Protein Kinase Inhibitors (e.g., ceritinib, crizotinib, nilotinib): Some of these can interfere with budesonide metabolism. • Strong CYP3A4 Inhibitors (e.g., antifungals like ketoconazole, itraconazole, voriconazole, posaconazole; HIV protease inhibitors like ritonavir, atazanavir, nelfinavir, lopinavir; macrolide antibiotics like clarithromycin, erythromycin; and other drugs like cobicistat, nefazodone, conivaptan): These drugs significantly inhibit the CYP3A4 enzyme, leading to a substantial increase in systemic budesonide exposure and a higher risk of corticosteroid-related side effects, such as adrenal suppression.
• Systemic corticosteroids (e.g., prednisone): If you are currently taking or have recently stopped taking oral corticosteroids, using PULMICORT NEBUAMP can increase the risk of systemic corticosteroid effects. Your doctor will need to manage the transition carefully to avoid adrenal insufficiency.

Grapefruit:
Grapefruit and grapefruit juice can interact with PULMICORT NEBUAMP by potentially increasing the systemic exposure to budesonide and raising the risk of side effects. It is important to discuss grapefruit consumption with your doctor for personalized guidance.

Pregnancy and Breastfeeding:

PULMICORT NEBUAMP should only be used during pregnancy if the potential benefits outweigh the risks to the fetus. Budesonide can pass into breast milk, and the potential effects on the nursing infant should be discussed with your doctor.

Children:

In children under 6 years of age, the safety and effectiveness of PULMICORT NEBUAMP have not been definitively established through clinical studies. Therefore, its use in this age group requires careful consideration by a healthcare professional.

For children receiving long-term treatment with PULMICORT NEBUAMP, there is a potential risk of impact on growth velocity. Consequently, regular monitoring of height is crucial to detect any significant deviations from expected growth patterns. This monitoring allows for timely reassessment of the treatment plan by the prescribing physician.

Frequently Asked Questions about PULMICORT NEBUAMP at Canada Pharmacy Online:

Why is PULMICORT NEBUAMP more affordable in Canada than in the United States?

Prescription drug prices, including PULMICORT NEBUAMP, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many packs I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of PULMICORT NEBUAMP at once, per your doctor's prescription.

Can I buy over the counter from you?

No, PULMICORT NEBUAMP requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for PULMICORT NEBUAMP?

Yes, there is a generic alternative for this product called budesonide.

What if I miss a dose?

Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the next dose to make up for a missed one.

How do I take PULMICORT NEBUAMP properly?

PULMICORT NEBUAMP is for use with a jet (pneumatic) nebulizer equipped with a mouthpiece or face mask with an appropriate flow rate generated by an air compressor. The nebulizer should be capable of producing respirable particles of an appropriate size for delivery to the lungs. Ultrasonic nebulizers should not be used as they may not deliver the medication effectively. Do not use with a respirator or ventilator circuit unless specifically directed by your doctor. Carefully read the Rpatient information leaflet that comes with your PULMICORT NEBUAMP. The leaflet contains specific instructions regarding the preparation and administration of your prescribed formulation using the recommended nebulizer device and settings. Always wash your hands thoroughly with soap and water before preparing and using the nebulizer.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
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