Topicort (Desoximetasone)

Name: Topicort
Brand: Bausch Health
SKU: 6127
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Topicort Gel

Manufacturer: Bausch Health

Country: Canada

Dosage: 0.05 %/60 gm

Qty-Price (USD):

Type:

Product: Topicort Mild Cream

Manufacturer: Bausch Health

Country: Canada

Dosage: 0.05 %/20 gm

Qty-Price (USD):

Type:

Product: Topicort Cream

Manufacturer: Bausch Health

Country: Canada

Dosage: 0.25 %/20 gm

Qty-Price (USD):

Type:

Product: Topicort Cream

Manufacturer: Bausch Health

Country: Canada

Dosage: 0.25 %/60 gm

Qty-Price (USD):

Type:

Product: Topicort Ointment

Manufacturer: Bausch Health

Country: Canada

Dosage: 0.25 %/60 gm

Qty-Price (USD):

Generic Equivalent of Topicort

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no generic product of Topicort.

Topicort Information

medically reviewed by Carol Hou (BSc. Pharm) on August 13, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Topicort at CanadaPharmacyOnline.com

Topicort, a brand-name desoximetasone, is manufactured and distributed in Canada by Bausch Health.

Generic desoximetasone is currently unavailable (at this pharmacy).

Dosage

Topicort (desoximetasone) is available in various topical forms and strengths (at this pharmacy):
• Gel: 0.05% in 60 g tubes
• Creams:
o Mild Cream: 0.05% in 20 g tubes
o Cream: 0.25% in 20 g and 60 g tubes
• Ointment: 0.25% in 20 g and 60 g tubes

Your doctor will determine the appropriate dose based on your individual needs and medical history.

Usage

Topicort (desoximetasone) is a prescription medication used to treat a variety of inflammatory and pruritic (itchy) skin conditions that are responsive to corticosteroids. These conditions include:
• Allergic reactions
• Eczema (atopic dermatitis)
• Psoriasis (including plaque psoriasis)
• Other dermatoses (skin inflammations) where corticosteroids are indicated to reduce redness, itching, and swelling.

Mechanism of Action
Topicort (desoximetasone) is a synthetic corticosteroid. Like other topical corticosteroids, it works by diffusing across cell membranes and binding to specific glucocorticoid receptors in the cytoplasm. This complex then translocates to the nucleus, where it modulates gene expression. This leads to the synthesis of anti-inflammatory proteins and the inhibition of inflammatory mediators such as prostaglandins and leukotrienes. These actions result in its anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive (blood vessel narrowing) effects, which help to reduce the redness, swelling, and itching associated with various skin conditions. While systemic absorption is generally minimal with topical use, it can suppress the hypothalamic-pituitary-adrenal (HPA) axis, particularly with prolonged use, extensive application, or occlusive dressings.

Take Topicort exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Topicort, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Topicort, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common Side Effects - The following are some common side effects of Topicort, typically localized to the application site; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Acne or pimples
• Burning, itching, irritation, or dryness at the application site
• Changes in skin colour
• Folliculitis (inflammation of hair follicles)
• Hypertrichosis (increased hair growth)
• Perioral dermatitis (rash around the mouth)
• Skin atrophy (thinning of the skin, often with prolonged use)
• Striae (stretch marks, especially in skin folds)
• Telangiectasias (spider veins)

Serious Side Effects - These are rare but potentially severe side effects, often related to systemic absorption with prolonged or extensive use. Seek immediate medical attention or call emergency services if you experience any of the following:
• Adrenal suppression (Cushing's syndrome or adrenal insufficiency): Symptoms may include weight gain in the upper back or belly, round "moon" face, severe headache, slow healing, extreme tiredness, muscle weakness, mood changes, decreased appetite, or weight loss. This is more likely with prolonged use, high potency, or large treatment areas, especially in children.
• Allergic reactions: Severe rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing, wheezing, and itching.
• Eye problems: Blurred vision, tunnel vision, eye pain, or seeing halos around lights, increased intraocular pressure, glaucoma, or cataracts, especially if applied near the eyes.
• High blood sugar (hyperglycemia): Increased thirst, increased urination, dry mouth, or fruity breath odour.
• Infections: Worsening of existing skin infections or new infections due to immune suppression.
• Rebound flare-ups of skin conditions occur upon discontinuation of the medication, especially after prolonged use.
• Severe skin reactions: Redness, warmth, swelling, oozing, or severe irritation of any treated skin, indicating a possible allergic reaction or infection.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Topicort, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Topicort should not be used if you:
• Have a known hypersensitivity or allergy to desoximetasone, other corticosteroids, or any of the product's ingredients.
• Have certain viral, fungal, or bacterial skin infections that are untreated.
• Intend to use it in your eyes (for ophthalmic use).

Tell your doctor about all of your medical conditions, past and present, before starting Topicort. This is crucial because certain conditions affect whether Topicort is right for you. These conditions may include, but are not limited to:
• Any skin infection (bacterial, fungal, viral) at the treatment site
• Diabetes mellitus (may affect blood sugar control)
• Diaper rash (should not be used unless specifically prescribed by a doctor due to increased absorption risk in infants)
• Impaired circulation or other skin conditions that might affect absorption
• Impaired liver function (may affect the metabolism of absorbed drugs)
• Presence of large open wounds or damaged skin
• Rosacea or perioral dermatitis (corticosteroids can worsen these conditions)r> • Thinning of the skin (atrophy) at the proposed application site • Use with occlusive dressing (e.g., tight bandages, plastic wrap), as this can significantly increase absorption and side effects.

Drug Interactions

Before taking Topicort, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the Topicort prescribing information | Bausch Health.

Provide your doctor with a complete list of everything you take, including:
• All prescriptions and over-the-counter (OTC) medications.
• Vitamins, herbal supplements, and teas.
• Any recreational drugs or significant dietary changes.

While Topicort is a topical medication and generally has low systemic interaction risks, interactions can occur, especially with extensive or long-term use.
Potential Drug Interactions:
• Other topical corticosteroids: Avoid using Topicort with other steroid creams unless your doctor tells you to. This can increase the risk of side effects.
• Immunosuppressants: If you are taking a medication to suppress your immune system (like cyclosporine), tell your doctor. Long-term use of Topicort may increase your risk of infection.
• Certain medications that affect liver enzymes (e.g., ketoconazole, ritonavir): These medications could theoretically increase your body's exposure to the steroid, so your doctor should be aware of them.

Pregnancy and Breastfeeding

It is not known if Topicort is safe to use during pregnancy. It should only be used if the potential benefit outweighs the potential risk to the baby. If you are pregnant or planning to become pregnant, talk to your doctor. If used, avoid extensive, large-amount, or long-term use.

It is unknown if Topicort passes into breast milk. Use with caution while breastfeeding and only under your doctor's guidance. If you do use it, do not apply it to the breast or nipple area to prevent the baby from accidentally swallowing it.

Use in the Elderly

No overall differences in safety or effectiveness have been observed between elderly and younger patients. However, elderly patients may have a higher incidence of concomitant diseases (e.g., diabetes, liver, or kidney problems) or medications that could affect the systemic absorption or metabolism of desoximetasone. Close monitoring for adverse effects and appropriate adjustments to treatment duration or frequency may be necessary based on individual skin fragility or other health conditions.

Use in Children

The safety and effectiveness of some Topicort formulations have not been established in children under 10 years of age. Always follow your doctor's specific instructions.

Topicort should be used with caution in children. Children, especially infants and toddlers, are more likely to absorb the medication through their skin than adults. This can lead to serious side effects.

Important Safety Guidelines:
• Avoid Diapers: Do not use the medication with tight-fitting diapers or other occlusive dressings, as this can increase absorption.
• Avoid Extensive Use: Do not apply Topicort over large areas of a child's body.
• Limited Use: Use the smallest amount of medication needed for the shortest possible time.
• Monitor for Side Effects: Your child's doctor will monitor for signs of systemic side effects, which can include slow growth or other hormonal issues.

Frequently Asked Questions about Topicort at Canada Pharmacy Online:

Why is Topicort more affordable in Canada than in the United States?

Prescription drug prices, including Topicort, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tubes/bottles I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Topicort at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Topicort requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to apply Topicort?

Topicort is typically applied twice daily, usually in the morning and evening, or as directed by your doctor. It can be used at any time of day, but consistency is key for effectiveness. Follow your doctor's specific instructions.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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