Wixela Inhub (Fluticasone Propionate/Salmeterol)

Name: Wixela Inhub
Brand: Mylan
SKU: 7673
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Wixela Inhub Inhalation Powder

Manufacturer: Mylan

Country: Canada

Dosage: 100 mcg/50 mcg/60 dose

Qty-Price (USD):

Type:

Product: Wixela Inhub Inhalation Powder

Manufacturer: Mylan

Country: Canada

Dosage: 250 mcg/50 mcg/60 dose

Qty-Price (USD):

Type:

Product: Wixela Inhub Inhalation Powder

Manufacturer: Mylan

Country: Canada

Dosage: 500 mcg/50 mcg/60 dose

Qty-Price (USD):

Generic Equivalent of Wixela Inhub

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Product

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There is no generic product of Wixela Inhub.

Wixela Inhub Information

medically reviewed by Carol Hou (BSc. Pharm) on May 13, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Wixela Inhub at CanadaPharmacyOnline.com

Brand Wixela Inhub (fluticasone propionate and salmeterol xinafoate), manufactured by Mylan, is available in Canada.

Dosage:

Wixela Inhub is a dry powder inhaler available in the following common strengths, each containing 60 doses:
• 100 mcg/50 mcg: 100 mcg of fluticasone propionate and 50 mcg of salmeterol per inhalation
• 250 mcg/50 mcg: 250 mcg of fluticasone propionate and 50 mcg of salmeterol per inhalation
• 500 mcg/50 mcg: 500 mcg of fluticasone propionate and 50 mcg of salmeterol per inhalation

Your doctor will determine the appropriate dose and treatment duration based on your individual needs and condition.

Usage:

Wixela Inhub (fluticasone propionate and salmeterol xinafoate) is a prescription medicine that controls asthma symptoms and prevents symptoms such as wheezing and shortness of breath. It contains two medicines: fluticasone propionate, an inhaled corticosteroid that helps to reduce inflammation in the lungs and salmeterol xinafoate, a long-acting beta2-adrenergic agonist (LABA) that helps to relax the muscles around the airways in your lungs, making it easier to breathe.

Wixela Inhub is used for the long-term maintenance treatment of asthma in adults and children 4 years and older. It is also used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, in adults. It is not used to treat sudden asthma symptoms. For more information, please refer to the product labeling information: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/208891Orig1s000lbl.pdf

Mechanism of Action:
Wixela Inhub contains two active components: fluticasone propionate, a corticosteroid with potent anti-inflammatory activity. It reduces inflammation in the airways by inhibiting the release of various inflammatory cells and mediators. Salmeterol xinafoate is a selective long-acting beta2-adrenergic receptor agonist. It relaxes bronchial smooth muscle by stimulating beta2 receptors, which leads to bronchodilation and improves airflow.

Use Wixela Inhub exactly as your doctor prescribes. Do not change your dose or stop using Wixela Inhub without talking to your doctor. Use Wixela Inhub every day, even if you do not have symptoms.

It is important to use the Inhub device correctly; follow the instructions in the patient information leaflet that comes with your medicine. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before using Wixela Inhub, discussing all possible aspects with your doctor or pharmacist is essential.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Wixela Inhub, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Wixela Inhub, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Back pain
• Easy bruising
• Cough, sore throat, hoarseness, throat irritation
• Diarrhea
• Difficulty speaking
• Dizziness
• Headache
• Inflammation of the sinuses (sinusitis)
• Muscle and bone pain
• Nasal congestion
• Oral thrush (fungal infection in the mouth and throat)
• Stomach upset, nausea, vomiting
• Upper respiratory infection

Serious or rare side effects: Stop using Wixela Inhub and seek immediate medical attention if you experience any of the following:
• Allergic reactions, including rash, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing or swallowing
• Cataracts or glaucoma (especially with long-term use)
• Chest pain
• Fast or irregular heartbeat, palpitations
• High blood sugar (hyperglycemia)
• Increased blood pressure
• Insomnia
• Mental health changes, including agitation, anxiety, depression, nervousness, or changes in behaviour
• Pneumonia and other lower respiratory infections
• Seizures
• Severe worsening of asthma or COPD symptoms, including shortness of breath and wheezing
• Signs and symptoms of adrenal suppression (e.g., fatigue, weakness, nausea, vomiting, low blood pressure), especially with prolonged use.

Long-term use of inhaled corticosteroids may be associated with reduced bone mineral density and the potential for growth suppression in children and adolescents. Your doctor will monitor your condition for these possibilities.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Wixela Inhub.

Wixela Inhub should not be used if:
• You are allergic to fluticasone propionate, salmeterol xinafoate, or any other ingredients in Wixela Inhub.
• You are having a sudden severe asthma attack or sudden worsening of COPD symptoms. Wixela Inhub is not a rescue inhaler.

Tell your doctor about all of your medical conditions, past and present, before starting Wixela Inhub. This is crucial because certain conditions can affect whether Wixela Inhub is right for you. These conditions may include, but are not limited to:
• Cardiovascular disorders (e.g., coronary artery disease, hypertension, heart failure)
• Diabetes mellitus
• Glaucoma or increased pressure in the eye
• Hyperthyroidism
• Immune system problems
• Kidney problems
• Liver problems
• Osteoporosis or low bone mineral density
• Seizure disorders
• Tuberculosis (TB) or other lung infections

Drug Interactions:

Before using Wixela Inhub, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Wixela Inhub product monograph from Canada: https://pdf.hres.ca/dpd_pm/00055254.PDF

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Wixela Inhub may interact with other medicines, including but not limited to beta-blockers, certain antidepressants (e.g., MAOIs, tricyclic antidepressants), diuretics (water pills), ketoconazole and other strong CYP3A4 inhibitors (may increase the levels of fluticasone and salmeterol), other long-acting beta2-adrenergic agonists (LABAs) or inhaled corticosteroids, stimulants (amphetamines), pr anticholinergic medications (e.g., diphenhydramine, atropine).

Pregnancy and Breastfeeding:

Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using Wixela Inhub. There is limited data on the use of fluticasone propionate and salmeterol xinafoate in pregnant or breastfeeding women. Wixela Inhub should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. It is not known if fluticasone propionate or salmeterol xinafoate passes into breast milk. Discuss the risks and benefits with your healthcare provider.

Use in Children:

The safety and effectiveness of Wixela Inhub for treating asthma have been established in children 4 years and older. Talk to your doctor before using this medication in children.

Frequently Asked Questions about Wixela Inhub at CanadaPharmacyOnline.com:

Why is Wixela Inhub more affordable in Canada than in the United States?

Prescription drug prices, including Wixela Inhub, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I buy over the counter from you?

No, Wixela Inhub requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

How long does it take for Wixela Inhub to work?

Wixela Inhub is a maintenance medication, and it may take several days to weeks of regular use to achieve its full effect in controlling asthma and COPD symptoms. It is important to continue using Wixela Inhub as prescribed, even if you feel better. It is not a rescue medication and will not immediately relieve sudden symptoms.

How do I prevent oral thrush?

Rinse your mouth thoroughly after every use of Dulera to reduce the risk of developing oral thrush.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

Is there a limit on how many inhalers I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Wixela Inhub at once, per your doctor's prescription.

What should I do if I miss a dose?

If you miss a dose of Wixela Inhub, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at your regular time. Do not use a double dose to make up for a missed one.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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