Keppra (Levetiracetam)

Name: Keppra
Brand: UCB Pharma
SKU: 2428
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Keppra Oral Solution

Manufacturer: UCB Pharma

Country: Turkey

Dosage: 100 mg/ml/300 ml

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: UCB Pharma

Country: Canada

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: UCB Pharma

Country: Turkey

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Keppra (ON BACKORDER)

Manufacturer: UCB Pharma

Country: United Kingdom

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: Brand

Country: Turkey

Dosage: 500 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: Brand

Country: India

Dosage: 500 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: UCB Pharma

Country: Canada

Dosage: 500 mg

Qty-Price (USD):

Type:

Product: Keppra (ON BACKORDER)

Manufacturer: UCB Pharma

Country: United Kingdom

Dosage: 500 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: UCB Pharma

Country: Canada

Dosage: 750 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: UCB Pharma

Country: United Kingdom

Dosage: 750 mg

Qty-Price (USD):

Type:

Product: Keppra

Manufacturer: UCB Pharma

Country: Turkey

Dosage: 1000 mg

Qty-Price (USD):

Type:

Product: Keppra (ON BACKORDER)

Manufacturer: UCB Pharma

Country: United Kingdom

Dosage: 1000 mg

Qty-Price (USD):

Generic Equivalent of Keppra

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Levetiracetam Oral Solution

Manufacturer: Generic

Country: Canada

Dosage: 100 mg/ml/300 ml

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: Canada

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: India

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: United Kingdom

Dosage: 250 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: Canada

Dosage: 500 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: India

Dosage: 500 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: Canada

Dosage: 750 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: United Kingdom

Dosage: 750 mg

Qty-Price (USD):

Type:

Product: Levetiracetam

Manufacturer: Generic

Country: United Kingdom

Dosage: 1000 mg

Qty-Price (USD):

Keppra Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on July 22, 2025.

Keppra and Levetiracetam at CanadaPharmacyOnline.com

The brand Keppra (levetiracetam) is manufactured and marketed by UCB Pharma.

Generic levetiracetam is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Keppra:

Generic levetiracetam contains the same active ingredient as the brand-name Keppra and is required to meet the same safety, effectiveness, and quality standards as the brand-name product. This means it is designed to work in the same way as levetiracetam, also known as Keppra. Studies have demonstrated bioequivalence between generic and brand-name levetiracetam, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic levetiracetam, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage

Keppra and generic levetiracetam are available in various formats and strengths, including:
• 100 mg/ml oral solution, packaged in 300 mL
• 250 mg oral tablets
• 500 mg oral tablets
• 750 mg oral tablets
• 1000 mg oral tablets

Your doctor will determine the appropriate dose based on your individual needs and medical history.

Usage

Keppra (levetiracetam) is a prescription medication used to treat various types of seizures in individuals with epilepsy. It is often used as an add-on therapy with other seizure medications. However, it can also be used as monotherapy for specific indications. Common uses include:
• Juvenile Myoclonic Epilepsy: Adjunctive therapy for myoclonic seizures in patients 12 years of age and older.
• Partial-Onset Seizures: Monotherapy or adjunctive therapy for partial-onset seizures with or without secondary generalization. As a monotherapy, Health Canada has approved it for use in patients 16 years of age or older. It is approved as an adjunct therapy for patients 1 month of age and older with epilepsy.
• Primary Generalized Tonic-Clonic Seizures: Adjunctive therapy for primary generalized tonic-clonic (PGTC) seizures in patients 6 years of age and older with idiopathic generalized epilepsy.

Mechanism of Action
Keppra (levetiracetam) is an anti-epileptic drug with a unique mechanism of action that differentiates it from most other AEDs. Its primary mechanism is thought to involve binding to synaptic vesicle protein 2A (SV2A), a protein found on the membranes of synaptic vesicles that are involved in neurotransmitter release. By binding to SV2A, levetiracetam is believed to modulate the release of neurotransmitters, thereby reducing neuronal excitability and preventing excessive electrical activity in the brain that leads to seizures. Levetiracetam does not appear to act through conventional mechanisms such as GABAergic, glutamatergic, or ion channel modulation that are typical of other AEDs.

Take Keppra exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Keppra, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Keppra, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common Side Effects - The following are some common side effects of Keppra; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Aggression or hostility (more common in children)
• Anorexia (loss of appetite)
• Asthenia (weakness)
• Behavioral changes (e.g., agitation, irritability, mood swings)
• Cough or cold-like symptoms (e.g., nasopharyngitis, rhinitis)
• Diarrhea
• Dizziness
• Drowsiness/Somnolence
• Fatigue
• Headache
• Nausea
• Vomiting

Serious Side Effects - These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Acute Kidney Injury: Sudden decrease in kidney function, including acute renal failure or interstitial nephritis.
• Allergic reactions (hypersensitivity):
• Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A rare but severe and potentially life-threatening reaction that may start with fever, rash, and/or swollen lymph nodes, and can progress to internal organ injury (liver, kidneys, lungs, heart, pancreas). Symptoms may appear 2 to 8 weeks after starting the medicine.
• Other severe skin reactions, such as Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN), include severe blistering, peeling skin rash, and painful sores in the mouth or around the eyes.
• Blood abnormalities: Reduced white blood cell count (increasing risk of infection), reduced red blood cell count (anemia, causing shortness of breath, unusual tiredness, pale skin), or decreased platelet count.
• Coordination difficulties: Ataxia (loss of coordination), abnormal gait, incoordination.
• Liver problems: Symptoms like yellowing of the skin or eyes (jaundice), dark urine, persistent nausea or vomiting, pale stools, unusual tiredness. • Mental/Behavioral Changes: New or worsening depression, anxiety, agitation, aggression, panic attacks, insomnia, confusion, hallucinations, paranoia, memory problems, or suicidal thoughts or behavior.
• Neurological effects: Seizures (especially if medication is stopped suddenly), worsening of seizures.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Keppra, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Keppra should not be used if:
• You are allergic to levetiracetam or any other ingredient in Keppra.
Tell your doctor about all of your medical conditions, past and present, before starting Keppra. This is crucial because certain conditions affect whether Keppra is right for you. These conditions may include, but are not limited to:
• History of suicidal thoughts or behavior, or depression.
• Kidney problems or impaired renal function (dose adjustment may be necessary).
• Liver impairment (dose adjustment is generally not needed).
• Psychiatric or behavioral issues (e.g., aggression, psychosis, depression).

Drug Interactions

Before taking Keppra, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the Keppra official product website | UCB.com at https://www.ucb.com/solutions/products/keppra.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Keppra. Keppra has a relatively low potential for drug interactions compared to many other anti-epileptic drugs because the cytochrome P450 enzyme system does not extensively metabolize it. However, it may interact with other medicines, but is not limited to:
• Laxatives (e.g., macrogol): Some reports suggest macrogol may decrease the effectiveness of oral levetiracetam.
• Methotrexate: There have been reports of reduced clearance of methotrexate when co-administered with levetiracetam, leading to increased methotrexate levels and potential toxicity. Close monitoring of methotrexate levels is advised.
• Other CNS depressants (e.g., benzodiazepines, opioids, sedatives): May cause additive CNS depression, leading to increased drowsiness, dizziness, or sedation.

Avoid alcohol while using Keppra. Concomitant use with alcohol may increase CNS depression, drowsiness, and dizziness.

Pregnancy and Breastfeeding

Keppra should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Epilepsy needs to be well-controlled during pregnancy, as uncontrolled seizures can harm both the mother and the baby. If you are pregnant or planning to become pregnant, discuss this with your doctor. Taking a high dose of folic acid (5mg a day) is often recommended before and during early pregnancy for women taking anti-epileptic drugs. Levetiracetam is excreted into breast milk in varying amounts. While the amount transferred to the infant is often small, there have been rare reports of side effects in breastfed babies such as drowsiness, vomiting, or not feeding well. If the mother requires Keppra, breastfeeding may continue. However, the infant should be monitored for adverse effects, especially in younger, exclusively breastfed infants. Consult your doctor for personalized advice.

Use in Children

Keppra is indicated for use in partial-onset seizures in children. As a monotherapy, Health Canada has approved it for use in patients 16 years of age or older. It is approved as an adjunct therapy for patients 1 month of age and older with partial-onset seizures. It is also approved for myoclonic seizures in patients 12 years of age and older, and for primary generalized tonic-clonic seizures in patients 6 years of age and older. The dosage for pediatric patients is based on weight. Children, particularly younger ones, may be more prone to behavioral/psychiatric adverse events such as irritability and aggression, and should be closely monitored.

Use in the Elderly

Elderly patients taking Keppra should be closely monitored, particularly for drowsiness, dizziness, fatigue, and an increased risk of falls. Renal function may be decreased in older adults, requiring dosage adjustments.

Frequently Asked Questions about Keppra at Canada Pharmacy Online:

Why is Keppra more affordable in Canada than in the United States?

Prescription drug prices, including Keppra, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Keppra at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Keppra requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to take Keppra?

Keppra can be taken with or without food. It is usually taken twice a day, about 12 hours apart. To help remember, try to take it first thing in the morning and at night. Consistent timing is essential to maintain stable drug levels and seizure control. Your doctor will provide specific instructions.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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