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Pentasa Extended Release (Mesalamine/5-AminoSalicylic Acid)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Pentasa Extended Release Enema (Box of 7)
Manufacturer: Ferring
Country: Canada
Dosage: 1 gm/100 ml
Qty-Price (USD):
Type: drug type
Product: Pentasa Extended Release Suppository
Manufacturer: Ferring
Country: Canada
Dosage: 1 gm/ supp
Qty-Price (USD):
Type: drug type
Product: Pentasa Extended Release Enema (Box of 7)
Manufacturer: Ferring
Country: Canada
Dosage: 4 gm/100 ml
Qty-Price (USD):
Type: drug type
Product: Pentasa Extended Release Tablet
Manufacturer: Ferring
Country: Canada
Dosage: 500 mg
Qty-Price (USD):
Type: drug type
Product: Pentasa Extended Release Tablet
Manufacturer: Ferring
Country: India
Dosage: 500 mg
Qty-Price (USD):
Type: drug type
Product: Pentasa Extended Release Tablet (ON BACKORDER)
Manufacturer: Ferring
Country: Turkey
Dosage: 500 mg
Qty-Price (USD):
Type: drug type
Product: Pentasa Extended Release Tablet
Manufacturer: Ferring
Country: Canada
Dosage: 1000 mg
Qty-Price (USD):

Generic Equivalent of Pentasa Extended Release
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no generic product of Pentasa Extended Release.

Pentasa Extended Release online Canadian Pharmacy

Pentasa Extended Release Information

portrait medically reviewed by Dr. HaVy Ngo, Pharmacist on July 15, 2025.

Pentasa Extended Release and Mesalamine/5-aminosalicylic acid at CanadaPharmacyOnline.com

Ferring's Brand Pentasa Extended Release is available in many countries worldwide, including Canada, India, and Turkey.

The generic mesalamine/5-aminosalicylic acid is currently unavailable (at this pharmacy).

Dosage:

Pentasa Extended Release is offered in various strengths and forms:
• Oral Forms: 500 mg and 1000 mg extended-release capsules/tablets.
• Rectal Forms:
o 1 gram extended-release suppository.
o 1 and 4 gram extended-release enema, typically in 100 mL packaging.

Your doctor will determine the appropriate dosage based on your needs and medical conditions.

Usage:

Pentasa Extended Release (mesalamine/5-aminosalicylic acid) is a prescription medication for ulcerative colitis and Crohn's disease. Ulcerative colitis affects the colon and rectum, causing inflammation and redness in the lining of the gut. Crohn's disease is a form of inflammatory bowel disease (IBD) that primarily affects the intestines but may occur anywhere from the mouth to the anus. Pentasa is also used for the long-term treatment of ulcerative colitis and Crohn's disease to maintain remission and prevent relapse.

Mechanism of Action:
Pentasa Extended Release (mesalamine/5-aminosalicylic acid) is an anti-inflammatory drug that acts directly on the colon's lining to reduce swelling and irritation. Although its mechanism of action is not particular, it likely works by blocking specific pathways in the body that produce chemicals (such as prostaglandins and leukotrienes) that cause inflammation. Because the drug is extended-release, it helps make sure the medicine reaches all parts of the colon. Use Pentasa exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor. Follow the instructions in the product monograph in Canada: https://pdf.hres.ca/dpd_pm/00077312.PDF. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before using Pentasa Extended Release, it is essential to discuss all potential side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

Below is a partial list of side effects; individual reactions can vary. Before starting Pentasa Extended Release, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects – The following are some common side effects of Pentasa Extended Release; however, other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abdominal pain
• Diarrhea
• Flatulence
• Headache
• Nausea
• Vomiting

Serious or rare side effects – Stop using Pentasa Extended Release and seek immediate medical attention right away if you experience any of the following:
• Acute tolerance syndrome, including abdominal pain, cramping, bloody diarrhea, fever, rash, and headache
• Allergic reactions, including angioedema, hives, and trouble breathing
• Inflammation of the heart muscle, including chest pain, shortness of breath, or palpitations
• Liver problems, including vomiting, persistent nausea, dark urine, yellowing of the skin or eyes
• Photosensitivity

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are using with your doctor or pharmacist before starting Pentasa Extended Release.

Pentasa Extended-Release should not be used if:
• You are allergic to mesalamine/5-aminosalicylic acid or any of the inactive ingredients in Pentasa Extended Release
• You have a blockage of your urinary tract
• You have severe kidney impairment
• You have severe liver impairment
• You have a stomach or intestinal ulcer

Tell your doctor about your medical conditions, past and present, before starting Pentasa Extended Release. This is crucial because certain conditions can affect whether Pentasa Extended Release is proper for you. These conditions may include, but are not limited to:
• Heart problems
• Kidney problems
• Liver problems
• Lung problems
• Peptic ulcer
• Pyloric stenosis

Blood Tests:
Pentasa extended-release can cause abnormal blood test results. Your doctor will conduct frequent blood tests before and during treatment with Pentasa. The tests help your doctor monitor your liver and kidney function, as well as red and white blood cell counts, and other potential side effects.

Male Fertility:
Men taking Pentasa extended-release may experience decreased sperm count and sperm mobility. Discuss this risk with your doctor.

Photosensitivity:
Pentasa extended-release may increase your sensitivity to the sun. If you have a pre-existing skin condition, such as atopic dermatitis, you will likely experience this situation. Avoid sun exposure and use sunscreen when outdoors.

Drug Interactions:

Before using Pentasa Extended Release, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, please consult the Product Monograph | Ferring Pharmaceuticals: https://www.ferring.ca/media/1288/en-pentasa-pm_control-no-232612-en_25mar2022.pdf and discuss any concerns with your healthcare provider.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Pentasa Extended Release can interact with other medicines, but is not limited to;
• Furosemide: This can increase the serum concentrations of Pentasa in the body
• Nephrotoxic agents (e.g., ibuprofen, azathioprine, naproxen): These can increase the risk of kidney adverse reactions
• Thiopurines (e.g., azathioprine, mercaptopurine): These increase the risk of bone marrow suppression
• Warfarin: Pentasa may increase the anticoagulant effects of warfarin

Pregnancy and Breastfeeding:

If you are pregnant or become pregnant, tell your doctor before using Pentasa Extended Release. This medicine may affect an unborn baby. The drug can cause blood disorders in a baby. It is essential to discuss the risks and benefits of using Pentasa Extended Release with your doctor before starting treatment. If you are breastfeeding or plan to breastfeed, inform your doctor. Mesalamine/5-aminosalicylic acid is excreted in human breast milk. It can cause unwanted side effects, such as diarrhea, in a nursing infant. Discuss the risks and benefits of using Pentasa Extended Release with your doctor before using it.

Frequently Asked Questions about Pentasa Extended Release at Canada Pharmacy Online

Why is Pentasa Extended Release more affordable in Canada than in the United States?

Prescription drug prices, including Pentasa Extended Release, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs than the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, please visit our How to Order page.

Is there a limit on the number of Pentasa Extended Release tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of three months of Pentasa Extended Release at once, as per your doctor's prescription.

Can I buy Pentasa Extended Release over the counter from you?

No, Pentasa Extended Release requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the difference between Pentasa Extended-Release 500 mg and 1000 mg?

The difference in dosage represents the amount of the drug's active ingredient (mesalamine/mesalamine/5-aminosalicylic acid).

How should I take Pentasa Extended Release Tablets?

Take Pentasa Extended Release exactly as prescribed by your doctor. Take the drug with meals. Your dose will depend on the condition being treated.

How should I use Pentasa Enema?

Use Pentasa enema exactly as prescribed by your doctor. If possible, empty your bowels before administering the enema. Use one enema nightly at bedtime. Retain the enema overnight for the best results.

How should I use Pentasa Suppository?

Use Pentasa suppository exactly as prescribed by your doctor. Empty your bowel if possible before administering the suppository. You may lubricate the suppository with a water-based lubricant to make the insertion easier. Keep the suppository in your rectum for as long as possible. If it comes out within the first 10 minutes of insertion, you can insert a new one.

Can I crush or chew a Pentasa Extended Release Tablet?

Swallow the extended-release oral tablet whole with a full glass of water. Do not crush or chew it.

How long will I need to take Pentasa Extended Release?

The duration of treatment depends on your condition and response. Pentasa Extended Release is often used for long-term maintenance to prevent flare-ups of ulcerative colitis.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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