Tarceva (Erlotinib)

Name: Tarceva
Brand: Hoffman - La Roche
SKU: 6538
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Tarceva Tablet

Manufacturer: Hoffman - La Roche

Country: Canada

Dosage: 25 mg

Qty-Price (USD):

Type:

Product: Tarceva Tablet

Manufacturer: Hoffman - La Roche

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Tarceva Tablet

Manufacturer: Hoffman - La Roche

Country: Canada

Dosage: 150 mg

Qty-Price (USD):

Generic Equivalent of Tarceva

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Erlotinib Tablet

Manufacturer: Generic

Country: Canada

Dosage: 25 mg

Qty-Price (USD):

Type:

Product: Erlotinib Tablet

Manufacturer: Generic

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Erlotinib Tablet

Manufacturer: Generic

Country: India

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Erlotinib Tablet

Manufacturer: Generic

Country: Canada

Dosage: 150 mg

Qty-Price (USD):

Type:

Product: Erlotinib Tablet

Manufacturer: Generic

Country: India

Dosage: 150 mg

Qty-Price (USD):

Tarceva Information

CanadaPharmacyOnline.com supplies only genuine Tarceva from Canada shipped using the Canadian packaging. This Tarceva is manufactured by Genetech Inc. (a member of Roche Group), the worldwide manufacturer of Tarceva. This offer is neither endorsed nor authorized by Genetech Inc. (the United States and Canadian distributor of Tarceva). CanadaPharmacyOnline.com has no affiliation whatsoever with Genetech Inc.

Tarceva and Erlotinib at CanadaPharmacyOnline.com

The manufacturer of brand-name Tarceva (erlotinib hydrochloride) in Canada is Hoffman-La Roche. It is available in many countries worldwide, including Canada.

Generic erlotinib is also available from different manufacturers in many countries worldwide, including Canada and India. The specific manufacturer of the dispensed medication may vary depending on pharmacy inventory. Generic erlotinib is sourced from manufacturers that meet applicable regulatory standards.

Important Information about Generic Erlotinib

Generic erlotinib contains the same active ingredient as brand-name Tarceva. It must meet the same effectiveness and quality standards. This means it is designed to work like Tarceva. Studies have shown that generic erlotinib is bioequivalent to brand-name Tarceva, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information on generic drug approval and bioequivalence, please visit “Access to Generic Drugs in Canada | Canada.ca”.

Dosage:

Tarceva (erlotinib) is available in the following oral strengths at this pharmacy:
• Tablets: 25 mg, 100 mg, and 150 mg oral tablets

Take at the same time each day. Do not stop treatment without consulting your oncologist. Dosage is individualized and depends on the condition being treated. If dose reduction is required due to side effects, doses may be reduced in 50 mg steps.

Usage:

Tarceva (erlotinib) is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor indicated as first-line treatment of patients with locally advanced or metastatic NSCLC whose tumors have EGFR-activating mutations, as maintenance therapy following platinum-based chemotherapy for NSCLC, and in combination with gemcitabine for first-line treatment of locally advanced, unresectable, or metastatic pancreatic cancer. EGFR mutation testing is required before starting Tarceva for NSCLC.

Mechanism of Action
Erlotinib is a targeted treatment known as an EGFR tyrosine kinase inhibitor. It blocks mutated pathways to stop cancer advancement. In many cases of non-small cell lung cancer, cancer cells carry a mutation in a protein called EGFR. This mutation constantly signals the cancer cells to multiply, grow, and spread. Erlotinib binds directly to the EGFR mutation, cutting off the transmission of those growth signals. Without these signals, the cancer cells stop growing and eventually die.

Take Tarceva exactly as your oncologist prescribes, following the instructions in the product monograph. Take on an empty stomach (at least 1 hour before or 2 hours after a meal). Avoid smoking during treatment, as smoking significantly reduces erlotinib blood levels. Swallow the tablets whole with a glass of water. Do not crush or split them.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Tarceva, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Tarceva (erlotinib). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Tarceva; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning.
• Acne-like skin rash
• Diarrhea
• Dry skin and itching
• Loss of appetite, nausea, or vomiting
• Mouth sores (stomatitis)
• Nail changes or paronychia

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Corneal or Ocular Toxicity: Eye pain, severe redness, watering, blurred vision, changes in vision, or light sensitivity. Stop Tarceva and seek urgent eye evaluation.
• Gastrointestinal Perforation: Sudden severe abdominal pain, fever, nausea, or vomiting. A rare but serious complication requiring emergency surgery.
• Hepatotoxicity (Liver Toxicity): Jaundice, dark urine, light-colored stools, or severe fatigue.
• Interstitial Lung Disease (ILD) / Pneumonitis: New or worsening shortness of breath, cough, or fever. ILD has occurred with erlotinib and can be fatal. Tarceva must be stopped immediately if ILD is confirmed. Risk is higher in Asian patients.
• Severe Skin Reactions: Bullous, blistering, painful, or exfoliative skin conditions (such as Stevens-Johnson syndrome/toxic epidermal necrolysis).

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Tarceva, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Tarceva/erlotinib if:
• Allergies: Known hypersensitivity to erlotinib or any ingredient in the tablet.

Tell your doctor about all of your medical conditions, past and present, before starting Tarceva. This is crucial as certain conditions affect the drug's safety.
• Dehydration (severe diarrhea or vomiting can spike erlotinib levels and cause kidney injury)
• Eye conditions (such as severe dry eye or corneal ulcers)
• Gastrointestinal disease (such as a history of ulcers or diverticulitis)
• If you smoke
• Liver or kidney disease
• Lung problems (such as a history of pulmonary fibrosis)

Drug Interactions:

Before taking Tarceva, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the product monograph at https://pdf.hres.ca/dpd_pm/00047154.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Tarceva. Tarceva may interact with other medicines, including but not limited to:
• Cigarette smoking significantly reduces erlotinib blood levels (by up to 2.5-fold). Smoking cessation is strongly encouraged during treatment.
• CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St. John's Wort): significantly reduce erlotinib levels; avoid concurrent use.
• CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir, grapefruit juice): Increase erlotinib levels; use with caution and consider dose reduction. Avoid grapefruit juice and grapefruit hybrids such as pomelos.
• Proton pump inhibitors (e.g., omeprazole, pantoprazole): Drugs that raise stomach pH significantly reduce erlotinib absorption. Avoid PPIs; if acid suppression is needed, use antacids (taken well apart from erlotinib) or H2 antagonists (taken 2 hours before or 10 hours after erlotinib).
• Warfarin and other anticoagulants: Erlotinib may increase warfarin's anticoagulant effect, elevating the risk of severe bleeding. Monitor INR closely.

Pregnancy and Breastfeeding:

Tarceva can cause harm to an unborn baby. Women of childbearing potential must use highly effective contraception during treatment and for at least 1 month after the final dose. Tarceva must not be used during pregnancy. Male patients with female partners of childbearing potential should also use effective contraception during treatment and for at least 1 month after the final dose. Breastfeeding is not recommended while taking Tarceva and for 2 weeks after the final dose; discuss with your doctor.

Use in Children:

The safety and efficacy of Tarceva in patients under 18 years of age have not been established. It is not recommended for use in children.

Frequently Asked Questions about Tarceva at Canada Pharmacy Online

Why is Tarceva more affordable in Canada than in the United States?

Prescription drug prices, including Tarceva, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Tarceva I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of Tarceva per your doctor's prescription.

Can I buy Tarceva from you over the counter?

No, Tarceva requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Tarceva?

Yes, the generic equivalent is currently available/

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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