Zofran (Ondansetron Hydrochloride Dihydrate)

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Zofran Dissolving Tab (ON BACKORDER)

Manufacturer: GSK

Country: United Kingdom

Dosage: 8 mg

Qty-Price (USD):

Generic Equivalent of Zofran

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Ondansetron Hydrochloride Dihydrate

Manufacturer: Generic

Country: Canada

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Ondansetron Hydrochloride Dihydrate

Manufacturer: Generic

Country: India

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Ondansetron Hydrochloride Dihydrate Orally Disintegrating Tablet

Manufacturer: Generic

Country: Canada

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Ondansetron Hydrochloride Dihydrate

Manufacturer: Generic

Country: Canada

Dosage: 8 mg

Qty-Price (USD):

Type:

Product: Ondansetron Hydrochloride Dihydrate

Manufacturer: Generic

Country: United Kingdom

Dosage: 8 mg

Qty-Price (USD):

Type:

Product: Ondansetron Hydrochloride Dihydrate Orally Disintegrating Tablet

Manufacturer: Generic

Country: Canada

Dosage: 8 mg

Qty-Price (USD):

Zofran Information

Zofran (Ondansetron) at CanadaPharmacyOnline.com

Brand Zofran (ondansetron) is manufactured by GSK, is available in many countries worldwide including, the United Kingdom. Generic ondansetron is sourced from manufacturers that meet applicable regulatory standards for safety, efficacy, and quality. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Ondansetron:

Generic ondansetron contains the same active ingredient as brand-name Zofran and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work the same way Zofran does. Studies have demonstrated bioequivalence between generic and brand-name ondansetron, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic ondansetron. For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Zofran (ondansetron) is available in various forms, including regular oral tablets and orally disintegrating tablets (ODT). The brand Zofran is available in various formulations, including 8 mg dissolving tablets. Generic ondansetron is available in 4 mg and 8 mg oral tablets and orally disintegrating tablets. Your doctor will determine the appropriate dosage and route of administration based on the individual needs and health situation.

Usage:

Zofran (ondansetron) is a prescription medication used to prevent nausea and vomiting associated with moderately emetogenic chemotherapy, highly emetogenic chemotherapy, and radiation therapy, including total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen. (see the product labeling information)

Mechanism of Action

Ondansetron is a selective 5-HT3 receptor antagonist. It works by blocking serotonin, a natural substance in the body that can cause nausea and vomiting. Specifically, it blocks serotonin receptors in the chemoreceptor trigger zone (CTZ) in the brain and peripherally on the vagal nerve terminals in the gastrointestinal tract. By blocking these receptors, ondansetron prevents the signals that trigger nausea and vomiting.

It is crucial to take Zofran exactly as your doctor prescribes and to complete the full course of treatment, even if you feel better. Follow your doctors’ instructions as well as instructions in the Norvartis | product monograph.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Zofran, it is essential to discuss all potential side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

This is a partial list of side effects; individual reactions can vary. Discuss all potential side effects and risks of Zofran with your doctor or pharmacist before starting this medication.

Common side effects – The following are some common side effects of Ondansetron, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Constipation;
• Diarrhea;
• Dizziness;
• Headache;
• Lightheadedness;
• Tiredness.

Serious or rare side effects – Stop taking Zofran and seek immediate medical attention right away if you experience any of the following symptoms:
• Allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing;
• Chest pain;
• Fast or irregular heartbeat;
• Fainting;
• Headache accompanied by chest pain and dizziness;
• Jaundice;
• Severe constipation, stomach pain, or bloating;
• Signs of serotonin syndrome (agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, loss of coordination);
• Vision changes.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Zofran.

Zofran should not be used if:
• You are allergic to ondansetron or any of its ingredients.
• You are also taking apomorphine.

Tell your doctor about all of your medical conditions, past and present, before starting Zofran. This is crucial because certain conditions can affect whether Zofran is right for you. These conditions may include, but are not limited to:
• Allergies to Dolasetron, Granisetron, or palonosetron;
• A blockage in your digestive tract (stomach or intestines);
• Electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
• Heart problems, including congenital long QT syndrome or congestive heart failure;
• Liver disease;
• Phenylketonuria (PKU), if taking the orally disintegrating tablets.

Drug Interactions:

Before taking Zofran, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, consult the official Zofran prescribing information and discuss any concerns with your healthcare provider. Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Zofran can interact with several medications, including (but not limited to) apomorphine, antidepressants, antipsychotics, opioid medications, rifampin, and other medications used to prevent nausea or vomiting.

Dizziness and Drowsiness:
Zofran may cause dizziness or drowsiness. Avoid driving, operating machinery, or engaging in activities that require alertness until you understand how it affects you.

Pregnancy and Breastfeeding:

If you are pregnant, have become pregnant, are breastfeeding, or plan to breastfeed, it is crucial to discuss the risks and benefits of using Zofran with your doctor before taking it.

Frequently Asked Questions about Zofran at Canada Pharmacy Online:

Why is Zofran more affordable in Canada than in the United States?

Prescription drug prices, including Zofran, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I take Zofran with food?

Zofran can be taken with or without food. However, always follow your doctor’s instructions.

Can I crush or chew Zofran tablets?

Regular Zofran tablets should be swallowed whole. Orally disintegrating tablets (ODT) should be allowed to dissolve on the tongue. Consult your doctor or pharmacist if you have difficulty swallowing tablets.

Will Zofran cure my nausea?

Zofran is designed to prevent nausea and vomiting, not cure the underlying cause. Consult your doctor to determine the cause of your nausea and appropriate treatment.

Can Zofran be used for morning sickness during pregnancy?

While Zofran is sometimes prescribed for severe nausea and vomiting during pregnancy, especially hyperemesis gravidarum, it's crucial to discuss the risks and benefits with your doctor. They can assess your specific situation and determine the most appropriate treatment.

How quickly does Zofran start working?

Zofran typically starts working within 30 minutes to an hour after taking it orally.

What should I do if I miss a dose of Zofran?

If you miss a dose of Zofran, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high quality products.

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This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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