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Seasonique (Levonorgestrel/Ethinyl Estradiol)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Seasonique 91 pills pack (ON BACKORDER)
Manufacturer: Teva
Country: Canada
Dosage: 0.15 mg/0.03 mg
Qty-Price (USD):

Generic Equivalent of Seasonique
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no generic product of Seasonique.

Seasonique Information

Seasonique at CanadaPharmacyOnline.com

The manufacturer of brand-name Seasonique is Teva Pharmaceuticals (Teva Canada Ltd.), one of the world’s leading generic and specialty pharmaceutical companies. Seasonique is currently available at this pharmacy as the brand-name product, manufactured by Teva and distributed from Canada.

There is currently no generic equivalent available for Seasonique at this pharmacy.

Dosage:

Seasonique is available in this oral form and strength:
• Extended-Cycle Tablet Dispenser (91-pill pack / 13-week supply)

The dosage of Seasonique is one light blue-green tablet taken daily for 84 consecutive days, followed by one yellow ethinyl estradiol tablet daily for 7 days, for a total of 91 days (13 weeks) per cycle. You can expect approximately 4 withdrawal bleeding periods per year, occurring during the 7-day yellow tablet phase. Begin taking Seasonique on the first Sunday after the onset of menstruation. If menstruation begins on a Sunday, start that same day. A non-hormonal backup method of contraception should be used for the first 7 days of starting the tablet.

Usage:

Seasonique is an extended-cycle combination oral contraceptive (COC) indicated for use by females of reproductive potential to prevent pregnancy. It belongs to a class of extended-cycle OCPs that reduce the frequency of withdrawal bleeding from the conventional monthly schedule to approximately four times per year. Unlike conventional 28-day pills that include a hormone-free interval every month, Seasonique’s 84/7 regimen provides continuous hormone exposure for 84 days. It replaces the traditional placebo week with 7 days of low-dose ethinyl estradiol (0.01 mg). This low-dose estrogen during what would otherwise be the pill-free interval helps reduce the breakthrough bleeding and spotting that is common with other extended-cycle regimens, and may also minimize estrogen-withdrawal symptoms such as headaches and bloating.

Non-contraceptive benefits may include lighter periods, reduced menstrual cramping (dysmenorrhea), and potentially a lower risk of ovarian and endometrial cancers with long-term use. Seasonique does not protect against HIV (AIDS) or other sexually transmitted infections (STIs).

Mechanism of Action
Seasonique works through the combined actions of its two hormones: levonorgestrel (a second-generation progestin) and ethinyl estradiol (a synthetic estrogen). Combination oral contraceptives primarily lower the risk of pregnancy by suppressing ovulation. Levonorgestrel acts centrally to inhibit the surge of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, preventing follicular development and the release of an egg. Ethinyl estradiol reinforces this effect by inhibiting follicular development.

In addition to suppressing ovulation, the hormones in Seasonique produce two secondary mechanisms: they thicken the cervical mucus, making it difficult for sperm to penetrate and reach any egg that may have been released, and they alter the endometrial lining of the uterus, reducing the likelihood of implantation should fertilization occur. The unique feature of Seasonique is the very low ethinyl estradiol dose (0.01 mg) in the 7 yellow tablets. Rather than providing a complete hormone-free week (which would normally trigger a full withdrawal bleed and estrogen-withdrawal symptoms), this low-dose estrogen maintains a minimal hormonal baseline, smoothing the transition between cycles and reducing the incidence of breakthrough bleeding seen with other extended-cycle formulations.

Take Seasonique exactly as your doctor prescribes, according to the instructions in the product monograph. Tablets should be taken in the order directed on the blister pack, at the same time each day, and at intervals not exceeding 24 hours.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Seasonique, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Seasonique (levonorgestrel/ethinyl estradiol). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Seasonique; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Acne (may improve or worsen)
• Breast pain or tenderness
• Changes in vaginal discharge
• Decreased libido
• Irregular or unscheduled vaginal bleeding or spotting (the most common side effect, especially in the first few cycles. This typically decreases over time)
• Nausea
• Weight gain

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Blood Clots (Venous Thromboembolism/VTE): Pain, swelling, or warmth in the leg, sudden shortness of breath, chest pain or pressure, coughing up blood.
• High Blood Pressure: Discontinue Seasonique if blood pressure rises significantly. Women with uncontrolled hypertension should not use COCs.
• Liver Problems: Yellowing of the eyes or skin (jaundice), dark urine, and severe upper stomach pain. Discontinue Seasonique if jaundice occurs.
• Severe Abdominal Pain: Could indicate gallbladder problems or a rare liver tumor (hepatocellular adenoma). Discontinue if this occurs.
• Severe Allergic Reaction (Anaphylaxis): Rash, itching, swelling of the face, tongue, or throat, or difficulty breathing.
• Stroke or Heart Attack: Sudden numbness or weakness (especially on one side of the body), sudden severe headache, dizziness, or trouble speaking, vision changes.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Seasonique, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Seasonique/levonorgestrel/ethinyl estradiol if:
• Allergies: You have a known hypersensitivity to levonorgestrel, ethinyl estradiol, or any ingredient in the tablet.
• Blood Clot History: You have a current or past history of deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, or heart attack, or have a high risk of arterial or venous thrombotic diseases.
• Liver Disease: Current or past history of liver tumours (benign or malignant), or active liver disease with abnormal liver function.
• Migraine with Aura: A history of migraine headaches with focal neurological symptoms (aura).
• Pregnancy: Seasonique is contraindicated during pregnancy. Discontinue if pregnancy is confirmed.
• Smoking and Age: You are over 35 years of age and smoke. Cigarette smoking increases the risk of serious cardiovascular events from COC use.
• Undiagnosed Vaginal Bleeding: Any abnormal uterine bleeding that has not been investigated.

Tell your doctor about all of your medical conditions, past and present, before starting Seasonique. Conditions requiring extra monitoring or caution include:
• A history of seizures
• A history of severe depression or mood disorders
• Chloasma (dark patches of facial skin that developed during a previous pregnancy or COC use, limit sun and UV exposure)
• Diabetes mellitus with vascular involvement
• Hereditary angioedema (COCs may worsen this condition)
• Hyperlipidemia – certain progestins may raise LDL levels
• Hypertension (high blood pressure) – well-controlled hypertension should be monitored closely.
• Inflammatory bowel disease (Crohn’s disease or ulcerative colitis)

Drug Interactions:

Before taking Seasonique, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please refer to the product monograph at https://pdf.hres.ca/dpd_pm/00074631.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Seasonique. Seasonique may interact with other medicines, including but not limited to:
• Anastrozole (and other aromatase inhibitors or anti-estrogens): Ethinyl estradiol can interfere with the pharmacological action of these drugs. Concomitant use is not recommended.
• Cyclosporine, Theophylline, and Prednisolone: Ethinyl estradiol may inhibit the metabolism of these drugs, increasing their plasma levels.
• Enzyme Inducers (Drugs That May Decrease Effectiveness): Certain anticonvulsants, such as phenytoin, carbamazepine, oxcarbazepine, topiramate, felbamate, and phenobarbital, the anti-tuberculosis drug rifampin (rifampicin), and the herbal supplement St. John’s Wort (Hypericum perforatum) can significantly reduce plasma levels of levonorgestrel and ethinyl estradiol, potentially decreasing contraceptive effectiveness and increasing breakthrough bleeding.
• HIV Antiretrovirals and Hepatitis C Drugs: Certain HIV protease inhibitors, non-nucleoside reverse transcriptase inhibitors (NNRTIs), and hepatitis C regimens (e.g., ritonavir-boosted regimens) can significantly alter estrogen and progestin levels. The effects vary widely by agent; some increase hormone levels, others decrease them. Consult your doctor and discuss the need for backup contraception.
• Lamotrigine (an anticonvulsant): COCs may significantly decrease lamotrigine plasma levels, potentially reducing seizure control. Lamotrigine dose adjustments may be needed when starting, stopping, or changing the dose of Seasonique.
• Thyroid Replacement Therapy: Seasonique may increase thyroid-binding protein levels. If you are taking thyroid medication, your doctor may need to adjust your dose after you start Seasonique.

Pregnancy and Breastfeeding:

Seasonique is contraindicated during pregnancy. It must be discontinued immediately if pregnancy is confirmed, as there is no reason to use hormonal contraceptives during pregnancy. Seasonique is not recommended for use during breastfeeding. Small amounts of oral contraceptive steroids and metabolites are identified in breast milk. In addition, estrogen-containing COCs may decrease the quantity and quality of breast milk in nursing mothers.

Use in Children:

Do not use Seasonique in children before menarche (the onset of the first menstrual period).

Frequently Asked Questions about Seasonique at Canada Pharmacy Online

Why is Seasonique more affordable in Canada than in the United States?

Prescription drug prices, including Seasonique, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Seasonique I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Seasonique per prescription from your doctor.

Can I buy Seasonique from you over the counter?

No, Seasonique requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Seasonique?

There is currently no generic equivalent available for Seasonique at this pharmacy.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
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