Breztri Aerosphere (Budesonide/Glycopyrrolate/Formoterol Fumarate)

Name: Breztri Aerosphere
Brand: AstraZeneca
SKU: 7721
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Breztri Aerosphere 120 actuations Inhaler

Manufacturer: AstraZeneca

Country: Canada

Dosage: 160 mcg/7.2 mcg/5 mcg

Qty-Price (USD):

Type:

Product: Breztri Aerosphere 120 Dose Inhaler

Manufacturer: AstraZeneca

Country: Australia

Dosage: 160 mcg/7.2 mcg/5 mcg

Qty-Price (USD):

Type:

Product: Breztri Aerosphere 120 Dose Inhaler

Manufacturer: AstraZeneca

Country: United Kingdom

Dosage: 160 mcg/7.2 mcg/5 mcg

Qty-Price (USD):

Generic Equivalent of Breztri Aerosphere

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Budesonide/Glycopyrrolate/Formoterol Fumarate 120 Dose Inhaler

Manufacturer: Generic

Country: India

Dosage: 160 mcg/9 mcg/4.8 mcg

Qty-Price (USD):

Breztri Aerosphere Information

medically reviewed by Carol Hou (BSc. Pharm) on July 4, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Breztri Aerosphere and Budesonide/Glycopyrrolate/Formoterol Fumarate at CanadaPharmacyOnline.com

Brand Breztri Aerosphere, known as Trixeo Aerosphere, manufactured by AstraZeneca, is available in many countries worldwide, including Canada, Australia, and the United Kingdom.

Generic budesonide/glycopyrrolate/formoterol fumarate is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Budesonide/glycopyrrolate/formoterol fumarate:

Generic budesonide/glycopyrrolate/formoterol fumarate contains the same active ingredients as the brand-name Breztri Aerosphere and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Breztri Aerosphere. Studies have demonstrated bioequivalence between generic and brand-name budesonide/glycopyrrolate/formoterol fumarate, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic budesonide, glycopyrrolate, and formoterol fumarate, please consult your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Breztri Aerosphere is available at 160 mcg/7.2 mcg/5 mcg and is formulated as 160 mcg of budesonide, 7.2 mcg of glycopyrrolate, and 5 mcg of formoterol fumarate per actuation, providing 120 doses per inhaler.

A generic version containing budesonide, glycopyrrolate, and formoterol fumarate is also available with a formulation of 160 mcg/9 mcg/4.8 mcg per actuation for a 120-dose inhaler.

Your doctor will determine the appropriate dosage based on the individual needs and medical conditions.

Usage:

Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate) is a prescription medication used to treat chronic obstructive pulmonary disease (COPD), a progressive lung disease that makes breathing difficult. The condition includes chronic bronchitis and emphysema, both of which damage the airways and air sacs in the lungs. Breztri Aerosphere is not used to relieve sudden breathing problems or to treat asthma.

Mechanism of Action:
Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate) is a combination of 3 active ingredients. Budesonide is an inhaled corticosteroid (ICS) that reduces inflammation in the airways. Glycopyrrolate is a long-acting muscarinic antagonist (LAMA) that relaxes the muscles around the airways, keeping them open. Formoterol Fumarate is a long-acting beta2-adrenergic agonist (LABA) that also relaxes the muscles around the airways, making breathing easier. The three active ingredients work together to reduce inflammation and open the airways, thereby improving breathing and reducing symptoms of COPD. Use Breztri Aerosphere exactly as your doctor prescribes, following the instructions in the consumer information leaflet. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before using Breztri Aerosphere, it is essential to discuss all potential side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Breztri Aerosphere, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects – The following are examples of some common side effects of Breztri Aerosphere; other side effects may also occur. Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms. • Back pain • Cough • Diarrhea • Muscle spasms • Oral thrush in the mouth and throat

Serious or rare side effects – Stop using Breztri Aerosphere and seek immediate medical attention right away if you experience any of the following:
• Allergic reactions, including angioedema, hives, and trouble breathing
• Signs of adrenal suppression, including unusual tiredness, weakness, dizziness, nausea, vomiting, or appetite loss
• Signs of pneumonia, including increased mucus production, change in mucus colour, fever, chills, increased cough
• Sudden worsening of breathing or wheezing (paradoxical bronchospasm)
• Urinary retention

Contraindications:

This is not an exhaustive list of contraindications. Before starting Breztri Aerosphere, it is essential to discuss all your medical conditions, past and present, as well as all medications you are currently taking, with your doctor or pharmacist.

Breztri Aerosphere should not be used if:
• Are allergic to budesonide, glycopyrrolate, formoterol fumarate, or any of the inactive ingredients in Breztri Aerosphere
• You are experiencing a sudden worsening of your COPD symptoms
• You have asthma

Tell your doctor about all of your medical conditions, past and present, before starting Breztri Aerosphere. This is crucial because certain conditions can affect whether Breztri Aerosphere is right for you. These conditions may include, but are not limited to:
• A history of lung infections, such as pneumonia
• A history of seizures
• Diabetes
• Eye conditions, such as glaucoma or cataracts
• Heart problems, such as heart disease, QT prolongation, rapid or irregular heartbeat
• High blood pressure
• Hypokalemia
• Kidney or liver problems
• Narrow-angle glaucoma
• Problems with your thyroid gland
• Untreated infections
• Urination problems

Acute Bronchospasm:
Breztri Aerosphere is a maintenance treatment for bronchospasm. It should not be used for acute episodes. For sudden breathing problems, use a separate rescue inhaler.

Asthma:
Breztri Aerosphere is not used in the treatment of asthma and may increase the risk of asthma-related death.

Bone Mineral Density:
Long-term use of inhaled corticosteroids can lead to a reduction in bone mineral density. Your doctor may monitor you for this.

Driving and Using Machinery:
Breztri Aerosphere can cause dizziness, blurred vision, headaches, or nausea, which may affect your ability to drive and operate machinery. Do not drive or perform any activity that requires alertness until you know how this medicine affects you.

Eye Problems:
Breztri Aerosphere can cause eye disorders like cataracts and glaucoma. If you notice any changes in your vision, inform your doctor immediately. You may need regular eye exams.

Hypokalemia and Hyperglycemia:
LABAs and corticosteroids can decrease serum potassium levels and increase blood glucose levels. Your doctor will monitor your blood glucose and potassium levels frequently.

Immunosuppression:
Budesonide, a corticosteroid, can weaken the immune system, increasing your risk of contracting infections such as chickenpox, measles, fungal infections, and tuberculosis. Avoid exposure to people with contagious diseases and inform your doctor if you develop signs of illness.

Oral Thrush:
Breztri Aerosphere can cause oral thrush, a fungal infection of the mouth and throat. To help prevent oral thrush, rinse your mouth with water after each use and spit it out.

Paradoxical Bronchospasm:
Breztri Aerosphere can cause paradoxical bronchospasm, a sudden worsening of breathing problems. If this occurs, stop using the medication immediately and use a rescue inhaler.

Drug Interactions:

Before using Breztri Aerosphere, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, consult the Product Monograph in Canada: https://pdf.hres.ca/dpd_pm/00074118.PDF and discuss any concerns with your healthcare provider.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Breztri Aerosphere can interact with other medicines but is not limited to ketoconazole, ritonavir, clarithromycin, tiotropium, salmeterol, and furosemide.

Pregnancy and Breastfeeding:

Limited data exist on the excretion of budesonide, glycopyrrolate, or formoterol fumarate in human breast milk. If you are breastfeeding, your doctor will weigh the potential risks and benefits to you and your baby before recommending Breztri Aerosphere. It's crucial to discuss the risks and benefits of using Breztri Aerosphere with your healthcare provider before starting treatment, especially if you are pregnant or become pregnant while using it.

Frequently Asked Questions about Breztri Aerosphere at Canada Pharmacy Online

Why is Breztri Aerosphere more affordable in Canada than in the United States?

Prescription drug prices, including Breztri Aerosphere, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs than the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Breztri Aerosphere I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Breztri Aerosphere at a time, as per your doctor's prescription.

Can I buy Breztri Aerosphere over the counter from you?

No, Breztri Aerosphere requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

How do I use Breztri Aerosphere?

Use exactly as prescribed by your doctor. It is usually administered as two inhalations, twice daily, in the morning and the evening. Shake the inhaler well before each use. It is essential to prime the inhaler before first use and when it has not been used for more than 7 days.

Is Breztri Aerosphere a rescue inhaler?

Breztri Aerosphere is a maintenance medication that should not be used for sudden breathing problems. You should have a separate rescue inhaler available to relieve shortness of breath immediately.

How will I know when the inhaler is empty?

The inhaler features a dose indicator that displays the number of sprays remaining. Discard the inhaler when the indicator shows zero.

Blog Posts:

Ellipta for COPD or Asthma? What You Should Know
What is Respimat? New Wonder Therapy for Asthma or COPD

Latest News:

Development and validation of a risk prediction model for depression in patients with chronic obstructive pulmonary disease (research published on July 3, 2025)

Similar Drugs in the category of Asthma Medication/ Respiratory Disorders:

Flovent Inhaler Advair Symbicort Inhalation Aerosol Spiriva Caps and Device Albuterol

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers