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Clomid (Clomiphene)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no brand product of Clomid.

Generic Equivalent of Clomid
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Clomiphene (Siphene - Serum Institute)
Manufacturer: Generic
Country: India
Dosage: 25 mg
Qty-Price (USD):
Type: drug type
Product: Clomiphene (Siphene - Serum Institute)
Manufacturer: Generic
Country: India
Dosage: 50 mg
Qty-Price (USD):
Type: drug type
Product: Clomiphene (Clome - Abbott)
Manufacturer: Generic
Country: India
Dosage: 100 mg
Qty-Price (USD):

Clomid Information

portrait medically reviewed by Carol Hou (BSc. Pharm) on June 12, 2025.
A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Clomiphene at CanadaPharmacyOnline.com

Currently, only generic clomiphene is available at this pharmacy.

Generic Clomiphene is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Clomiphene:

Generic clomiphene contains the same active ingredient as the brand-name Clomid. It is required to meet the same safety, effectiveness, and quality standards.

This means it is designed to work in the same way as Clomid. While bioequivalence studies are conducted to ensure generic medications have comparable absorption rates and overall effects, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using Clomiphene.

For information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Generic clomiphene is commonly available in strengths of 15 mg, 50 mg, and 100 mg oral tablets (at this pharmacy).

Your doctor will determine the appropriate dose and treatment duration based on your needs and medical condition.

Usage:

Brand Clomid is commonly used to help women struggling with infertility, particularly those who have difficulty ovulating regularly or at all. This helps to regulate menstrual cycles and increase the chances of conception.

For more information, refer to the product labelling information: https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/016131s026lbl.pdf.

Mechanism of Action:
Clomid (clomiphene) is a medication that primarily works to induce ovulation in women who have difficulty becoming pregnant due to irregular or absent ovulation. It acts as a selective estrogen receptor modulator (SERM), meaning it interacts with estrogen receptors in the brain, particularly in the hypothalamus. By binding to these receptors, Clomid essentially "tricks" the brain into perceiving lower-than-actual estrogen levels. In response, the brain releases more of the hormones crucial for ovulation: Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH). These increased hormone levels then stimulate the ovaries to develop and release mature eggs, making conception possible. This mechanism effectively kickstarts the body's natural ovulatory process when it's not functioning effectively on its own.

Use Clomid exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor and following the instructions on the official Clomid website: https://myclomid.com/. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Clomid, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Clomid, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Clomid, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abnormal Uterine Bleeding: Such as spotting or heavier-than-usual periods.
• Bloating and Abdominal Discomfort: A feeling of fullness, pressure, or mild pain in the abdomen or pelvis. This is often due to the ovaries being stimulated and slightly enlarging.
• Breast Tenderness: Similar to premenstrual breast discomfort.
• Dizziness or Light-headedness
• Headaches
• Hot Flashes: These are very common, similar to menopausal symptoms, and can involve sudden feelings of warmth, flushing, and sweating.
• Insomnia (trouble sleeping)
• Mood Swings/Irritability: Hormonal fluctuations caused by Clomid can lead to emotional changes, including moodiness, irritability, or even mild depression.
• Nausea or Vomiting
• Vaginal Dryness
• Visual Disturbances: This is a notable side effect, usually mild and temporary, but can include blurred vision, seeing spots or flashes of light, or increased sensitivity to light. If these occur, it's important to stop the medication and contact your doctor immediately.

Serious or rare side effects: Stop taking Clomid and seek immediate medical attention if you experience any of the following:
• Allergic Reactions: Signs include rash, hives, severe itching, swelling of the face, lips, tongue, or throat, or difficulty breathing.
• Liver Problems: Although rare, Clomid can potentially affect liver function. Symptoms might include yellowing of the skin or eyes (jaundice), dark urine, or unusual tiredness.
• More Severe Visual Disturbances: While mild visual changes are common, any significant or persistent changes, including blurred vision, double vision, or loss of vision, warrant immediate medical attention. In very rare cases, visual disturbances can be prolonged or permanent.
• Multiple Pregnancies: While not a side effect in the traditional sense, Clomid significantly increases the chance of having twins (about 5-10%), and rarely, triplets or more. This is an important consideration for many patients.
• Ovarian Hyperstimulation Syndrome (OHSS): This is a rare but potentially serious condition where the ovaries become excessively stimulated and enlarged. Symptoms can include severe abdominal pain and bloating, rapid weight gain, severe nausea and vomiting, diarrhea, decreased urination, and shortness of breath.
• Severe Abdominal or Pelvic Pain: Beyond typical mild bloating or discomfort, severe or persistent pain could indicate ovarian enlargement or OHSS.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Clomid.

Clomid should not be used if:
• Hypersensitivity or Allergic Reaction to Clomiphene Citrate: As with any medication, if a patient has a known allergy or severe hypersensitivity reaction to clomiphene citrate or any of its inactive ingredients, they should not use Clomid.

Tell your doctor about all your medical conditions, past and present, before starting Clomid. This is crucial because certain conditions can affect whether Clomid is right for you. These conditions may include, but are not limited to:
• Abnormal Uterine Bleeding of Undetermined Origin: If a woman experiences abnormal vaginal bleeding for which the cause has not been diagnosed, Clomid should not be used. This is because such bleeding could be a sign of underlying conditions like endometrial cancer or other serious issues that need to be ruled out before starting a fertility treatment.
• Hormone-Dependent Tumors: Clomid is contraindicated in patients with hormone-dependent tumors, such as certain types of breast cancer, as its hormonal effects could potentially stimulate the growth of these tumors.
• Liver Disease or History of Liver Dysfunction: Clomid is metabolized by the liver. Patients with active liver disease or a history of significant liver dysfunction should not use Clomid, as it could worsen liver damage.
• Organic Intracranial Lesion (e.g., Pituitary Tumor): Because Clomid acts on the pituitary gland (a part of the brain), any existing tumors or lesions in this area could be negatively affected or interfere with Clomid's action.
• Ovarian Cysts (Not Due to Polycystic Ovary Syndrome - PCOS): Clomid should not be used in the presence of an ovarian cyst or ovarian enlargement (other than the enlarged ovaries associated with PCOS). Clomid stimulates the ovaries, and existing cysts could enlarge further, potentially leading to complications. A pelvic exam is typically performed before each treatment cycle to check for this.
• Primary Ovarian Failure or Pituitary Failure: Clomid works by stimulating the natural hormonal axis. If a woman's ovaries or pituitary gland are no longer functioning (e.g., primary ovarian failure where ovaries cannot produce eggs, or primary pituitary failure where the pituitary cannot produce FSH/LH), Clomid will not be effective and should not be used.
• Uncontrolled Thyroid or Adrenal Dysfunction: The body's hormonal systems are interconnected. If a woman has uncontrolled issues with her thyroid or adrenal glands, these must be managed before starting Clomid, as they can interfere with ovulation or the effectiveness of Clomid.

Drug Interactions:

Before taking Clomid, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Clomid product monograph in Canada.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Clomid may interact with other medicines such as:
• Drugs that Affect Liver Enzymes: While Clomid is metabolized by the liver, it's not a strong inducer or inhibitor of the major CYP450 enzymes that process most drugs. However, medications that significantly affect liver enzyme activity could theoretically alter Clomid's levels, although this is generally not a major clinical concern for Clomid itself. Some specific drugs listed in databases (like certain oncology drugs, antivirals, or antifungals) can theoretically increase or decrease Clomid levels, but the clinical significance often needs to be evaluated on a case-by-case basis by a doctor.
• Herbal or Dietary Supplements: Some herbal supplements, such as certain forms of black cohosh or chasteberry, are sometimes used for hormonal balance. Their interaction with Clomid is not well-studied, but they could theoretically interfere with its effects or increase side effects. Always inform your doctor about any herbal or dietary supplements you are taking.
• Hormonal Contraceptives: Oral contraceptives prevent ovulation. They will counteract the intended effect of Clomid. Hormonal contraceptives should be discontinued before starting Clomid treatment.
• Ospemifene: Both Clomid and ospemifene are selective estrogen receptor modulators (SERMs). Taking them together can lead to additive anti-estrogenic effects, potentially increasing side effects or unintended hormonal imbalances. Increased effects of both drugs due to pharmacodynamic synergism. Concomitant use is generally contraindicated.
• Other Hormonal Medications, Especially Other Ovulation Inducers: Using Clomid with other hormonal medications that affect ovulation (e.g., gonadotropins like FSH or LH injections) can lead to an increased risk of Ovarian Hyperstimulation Syndrome (OHSS), a potentially serious condition where the ovaries become excessively stimulated. Greatly increased risk of OHSS and a higher chance of multiple pregnancies. Clomid should generally not be used concurrently with other ovulation-inducing drugs unless specifically directed and closely monitored by a fertility specialist, often as part of a controlled protocol.

Pregnancy and Breastfeeding:

Clomid (clomiphene) is generally not recommended if you are pregnant or breastfeeding. It is a medication used to help you get pregnant by inducing ovulation, so there is no benefit to taking it once you are already pregnant, and it is contraindicated. For breastfeeding mothers, Clomid is advised against because it can pass into breast milk, and there's a concern it might affect the infant's hormones or, more commonly, reduce your milk supply. Discuss the potential risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

Despite limited studies conducted in specialized research or clinical environments, Clomid (clomiphene citrate) is not a common or standard treatment for pediatric populations for any indication, including delayed puberty. If such off-label use exists, it's typically under very strict research protocols, not general clinical practice.

Frequently Asked Questions about Clomid at CanadaPharmacyOnline.com:

Why is Clomid more affordable in Canada than in the United States?

Prescription drug prices, including Clomid, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I buy over the counter from you?

No, Clomid requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Are men allowed to order this medication if they have a valid prescription?

Yes, men may order this medication for fertility and low sperm count. A valid prescription is required.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Blog Post:

Infertility Affects the Mental Health of Women and Men

News:

Global female infertility rates surge, hitting women in their late 30s hardest (article published on May 22, 2025)

Similar Drugs in the category of Fertility Drugs:

   Utrogestan    Endometrin    Cetrotide Injection SC    Menopur    Orgalutran

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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