Iopidine (apraclonidine)

Name: Iopidine
Brand: Essential Pharma
SKU: 5603
Availability: InStock

Type

Product

Manufacturer

Country

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Qty-Price (USD)

Type:

Product: Iopidine

Manufacturer: Essential Pharma

Country: Canada

Dosage: 0.5 %/5 ml

Qty-Price (USD):

Type:

Product: Iopidine 12 x 2 Plastic Dispensers Per Pack

Manufacturer: Novartis

Country: Canada

Dosage: 1 %/0.1 ml

Qty-Price (USD):

Generic Equivalent of Iopidine

Type

Product

Manufacturer

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Qty-Price (USD)

There is no generic product of Iopidine.

Iopidine Information

Iopidine at CanadaPharmacyOnline.com

The manufacturer of brand-name Iopidine (apraclonidine) is Alcon, with the Canadian license held by Novartis Pharmaceuticals Canada Inc. A version is also supplied from Canada by Essential Pharma. The drug is available in several countries worldwide, including Canada.

The generic apraclonidine is currently unavailable (at this pharmacy).

Dosage:

Iopidine is available in the following strengths and forms:
• 0.5% Ophthalmic Solution, in 5 mL bottles.
• 1% Ophthalmic Solution, in single-use plastic dispensers.

Iopidine 0.5% is typically used one to three times daily as short-term add-on therapy. Iopidine 1% is typically used as a single drop about an hour before certain laser eye procedures and another drop immediately after the procedure, to help prevent pressure spikes. Your doctor will determine the exact dosing schedule for your situation.

Usage:

Iopidine is used to reduce elevated pressure inside the eye (intraocular pressure). The 0.5% strength is used as short-term, add-on therapy in patients with glaucoma who are already on maximum tolerated medical therapy and need additional pressure lowering. The 1% strength is used to control or prevent spikes in eye pressure that can occur during or after certain laser eye surgeries, such as argon laser trabeculoplasty or laser iridotomy.

Mechanism of Action
Apraclonidine, the active ingredient in Iopidine, is an alpha-2 adrenergic agonist. It works primarily by reducing the amount of fluid (aqueous humor) produced by the ciliary body inside the eye and, to a lesser extent, by improving the rate at which this fluid drains out. Together, these actions lower the pressure inside the eye. Because apraclonidine acts on receptors similar to those of related medications like clonidine, it can also cause drowsiness, bradycardia (slow heart rate), or a mild lowering of blood pressure in certain patients.

Use Iopidine exactly as your doctor prescribes, according to the consumer information. Tilt your head back, pull down the lower eyelid, and instill 1 drop into the affected eye. Gently close the eye and press a finger against the inner corner of the eye (near the nose) for 1 to 2 minutes (nasolacrimal occlusion). This helps keep the drop in the eye and prevents it from draining into the bloodstream.

Iopidine typically begins working within about an hour, with the greatest pressure-lowering effect seen three to five hours after a dose. Iopidine 0.5% is intended for short-term use only (usually up to 1 month). Prolonged use often leads to loss of pressure-lowering effectiveness (tachyphylaxis) and a high risk of developing an ocular allergic reaction (itching, redness, tearing, and eyelid swelling). Do not use old or leftover Iopidine, since it loses effectiveness over time and is intended for short-term use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Iopidine, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Iopidine (apraclonidine). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Iopidine; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Blurred vision or dry eyes, or feeling like something is in the eye.
• Dizziness, drowsiness, or dry mouth and nose
• Eye redness, watering, itching, or puffy eyelids

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Eye Infection or Injury: Crusting or excessive discharge from the eye, increased eye pain, or sudden visual changes.
• Cardiovascular Effects: Irregular or significantly slowed heart rate, fainting, or chest discomfort.
• Severe Allergic Reaction: Hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Iopidine, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not use Iopidine if:
• Allergies: You have a known hypersensitivity to apraclonidine, clonidine, or any of the solution's ingredients.
• MAO Inhibitors: You are currently taking or have used a monoamine oxidase (MAO) inhibitor within the past 14 days.

Tell your doctor about all of your medical conditions, past and present, before starting Iopidine. This is crucial as certain conditions affect the drug's safety.
• Depression.
• Heart Disease, Including a History of Heart Attack, Angina, Severe Coronary Insufficiency, or Stroke.
• High or Low Blood Pressure
• Kidney or Liver Disease.
• Peripheral Vascular Disease or Raynaud's syndrome.

Drug Interactions:

Before using Iopidine, discuss all potential risks and interactions with your doctor or pharmacist. For complete, up-to-date information, please refer to the product monograph at https://hpr-rps.hres.ca/details.php?drugproductid=803&query=.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Iopidine. Iopidine may interact with other medicines, including but not limited to:
• Blood Pressure or Heart Rhythm Medications (such as beta-blockers, digitalis, or calcium channel blockers): These may interact with Iopidine's effects on blood pressure and heart rate.
• Central Nervous System (CNS) Depressants and Sedating Medications: Sleeping pills, narcotic pain medicines, muscle relaxants, alcohol, and certain antidepressants or antianxiety medications may add to Iopidine's drowsiness.
• Tricyclic Antidepressants: May affect the cardiovascular response to apraclonidine.

Pregnancy and Breastfeeding:

Iopidine is not recommended during pregnancy unless the potential benefit justifies the potential risk to the fetus. It is unknown whether apraclonidine passes into human milk, but because of the risk of serious adverse reactions in nursing infants, breastfeeding is generally not recommended while using this medication. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

The safety and effectiveness of Iopidine have not been established in children and adolescents under 18 years of age. Iopidine is contraindicated in pediatric patients due to the risk of severe systemic side effects. Systemic absorption of alpha-2 agonists in children can cause severe central nervous system depression, extreme lethargy, slow heart rate (bradycardia), low blood pressure, and breathing difficulty (apnea).

Frequently Asked Questions about Iopidine at Canada Pharmacy Online

Why is Iopidine more affordable in Canada than in the United States?

Prescription drug prices, including Iopidine, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Iopidine I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Iopidine per prescription from your doctor.

Can I buy Iopidine from you over the counter?

No, Iopidine requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Iopidine?

No, the generic apraclonidine is currently unavailable (at this pharmacy).

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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