Alphagan P (Brimonidine)

Name: Alphagan P
Brand: Allergan
SKU: 2520
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Alphagan P New Dosage (known as Alphagan Z from India)

Manufacturer: Allergan

Country: India

Dosage: 0.1 %/5 ml

Qty-Price (USD):

Type:

Product: Alphagan P Eye Drops

Manufacturer: Allergan

Country: India

Dosage: 0.15 %/5 ml

Qty-Price (USD):

Type:

Product: Alphagan P Eye Drops

Manufacturer: Abbvie

Country: Canada

Dosage: 0.15 %/10 ml

Qty-Price (USD):

Type:

Product: Alphagan P Eye Drops

Manufacturer: Abbvie

Country: Canada

Dosage: 0.15 %/5 ml

Qty-Price (USD):

Generic Equivalent of Alphagan P

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Brimonidine Eye Drops

Manufacturer: Generic

Country: Canada

Dosage: 0.15 %/10 ml

Qty-Price (USD):

Type:

Product: Brimonidine Eye Drops

Manufacturer: Generic

Country: Canada

Dosage: 0.15 %/5 ml

Qty-Price (USD):

Alphagan P Information

medically reviewed by Carol Hou (BSc. Pharm) on September 12, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Alphagan P and Brimonidine at CanadaPharmacyOnline.com

Alphagan P is manufactured and marketed by AbbVie in Canada. In other countries, such as India, the drug is produced by Allergan, a subsidiary of AbbVie.

Generic brimonidine is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Alphagan P:

Generic brimonidine contains the same active ingredient as the brand-name Alphagan P and is required to meet the same safety, effectiveness, and quality standards as the brand-name product. This means it's designed to work in the same way as brimonidine. Studies have demonstrated bioequivalence between generic and brand-name brimonidine, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic brimonidine, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage

Alphagan P is an ophthalmic solution of brimonidine, most commonly available in a 0.15% concentration. A 0.1% strength is also marketed as Alphagan P in some regions.

Your doctor will determine the appropriate dose based on your individual needs and medical history.

Usage

Alphagan P (brimonidine) is a prescription medication used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is typically used for long-term management and is not used to treat acute angle-closure glaucoma attacks.

Mechanism of Action
Brimonidine is a highly selective alpha-2 adrenergic receptor agonist that works by targeting specific receptors in the eye. The balance of aqueous humour production and drainage regulates the pressure inside the eye. By targeting these receptors, brimonidine provides a dual mechanism of action that reduces intraocular pressure:
• Increased Uveoscleral Outflow: It increases the drainage of aqueous humour through the uveoscleral pathway, an alternative route for fluid to exit the eye.
• Reduced Aqueous Humor Production: It decreases the production of aqueous humor by the ciliary body, the tissue responsible for fluid production in the eye.

This dual action provides a sustained reduction in IOP, helping to prevent damage to the optic nerve. Take Alphagan P exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Alphagan P, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Alphagan P, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common Side Effects - The following are some common side effects of Alphagan P; other side effects may also occur. Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms.
• Allergic conjunctivitis or eye irritation
• Blurred vision or visual disturbance
• Conjunctival folliculosis
• Dry mouth or oral dryness
• Eye itching or redness (hyperemia)
• Headache
• Somnolence (drowsiness)

Serious Side Effects - These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions: Severe rash, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing.
• Bradycardia (slowed heart rate) or hypotension (low blood pressure): Especially in vulnerable patients.
• Depression: New or worsening depression, or suicidal ideation.
• Ocular allergic reaction
• Severe eye pain or vision changes: Could indicate a serious eye condition.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Alphagan P, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Alphagan P should not be used if:
• You are allergic to brimonidine or any of the ingredients in the medication.
• You are taking or have recently taken a monoamine oxidase inhibitor (MAOI) within the last 14 days.
• You have a history of severe cardiovascular events like a heart attack, stroke, or transient ischemic attack (TIA).

Tell your doctor about all of your medical conditions, past and present, before starting Alphagan P. This is crucial because certain conditions affect whether Alphagan P is right for you. These conditions may include, but are not limited to:
• A history of cardiovascular disease (e.g., heart failure, coronary artery disease, or heart attack)
• A history of depression
• Hypotension (low blood pressure)
• Kidney or liver disease
• Raynaud's phenomenon (a condition causing reduced blood flow to the fingers and toes)
• Thromboangiitis obliterans (Buerger's disease)

Drug Interactions

Before taking Alphagan P, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the Alphagan P Patient Medication Information | AbbVie at https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/ALPHAGAN_P_PI_EN.pdf..

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Alphagan P may interact with other medicines, but is not limited to:
• Beta-blockers: When used with Alphagan P, beta-blockers, whether systemic (oral) or ophthalmic, can increase the risk of bradycardia and hypotension.
• CNS depressants: Medications like sedatives, opioids, barbiturates, or alcohol can have an additive depressive effect with Alphagan P, increasing the risk of somnolence.
• MAOIs: Monoamine oxidase inhibitors (MAOIs) can significantly increase the risk of hypotension with Alphagan P. The use of brimonidine is contraindicated within 14 days of stopping an MAOI.
• Tricyclic antidepressants: When used with Alphagan P, these medications can interfere with the blood pressure-lowering effects of brimonidine.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding. Alphagan P should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether brimonidine is excreted in human milk. Caution should be exercised when administering Alphagan P to a nursing woman.

Use in the Elderly

The safety and efficacy of Alphagan P in individuals aged 65 years and older have been evaluated, and no overall differences in safety were observed. However, due to a higher prevalence of underlying medical conditions in this age group, caution may be warranted.

Use in Children

Alphagan P is contraindicated for use in children under two years of age due to a high risk of somnolence (drowsiness) and apnea (cessation of breathing). The safety and efficacy in children aged two to twelve years has not been established, and a high rate of somnolence has been reported in clinical studies. Caution should be exercised when considering its use in this age group.

Frequently Asked Questions about Alphagan P at Canada Pharmacy Online:

Why is Alphagan P more affordable in Canada than in the United States?

Prescription drug prices, including Alphagan P, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Alphagan P at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Alphagan P requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to use Alphagan P?

Alphagan P is typically used three times daily, approximately 8 hours apart. Consistency is key for managing intraocular pressure, so it's essential to use it at the same time each day as prescribed by your doctor.

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Latest News:

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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