Leucovorin Calcium (Calcium Folinate)

Name: Leucovorin Calcium
Brand: Pfizer
SKU: 6534
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Leucovorin Calcium Tablet

Manufacturer: Pfizer

Country: Canada

Dosage: 5 mg

Qty-Price (USD):

Generic Equivalent of Leucovorin Calcium

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Calcium Folinate Tablet (Riva Pharma)

Manufacturer: Generic

Country: Canada

Dosage: 5 mg

Qty-Price (USD):

Type:

Product: Calcium Folinate Tablet

Manufacturer: Generic

Country: New Zealand

Dosage: 15 mg

Qty-Price (USD):

Leucovorin Calcium Information

Leucovorin Calcium at CanadaPharmacyOnline.com

Brand Leucovorin Calcium (calcium folinate) is manufactured by Pfizer in many countries worldwide, including Canada. Generic calcium folinate is available in many countries worldwide, including Canada and New Zealand. It is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Calcium folinate:

Generic calcium folinate contains the same active ingredient as the brand-name Leucovorin Calcium. It must meet the same safety, effectiveness, and quality standards as the brand-name product. This means it is designed to work in the same way as Leucovorin Calcium. Studies have demonstrated bioequivalence between generic and brand-name calcium folinate, indicating comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic calcium folinate, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand Leucovorin Calcium is commonly available as 5 mg oral tablets. Generic calcium folinate is also available as 5 mg and 15 mg oral tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Leucovorin Calcium (calcium folinate) is a prescription medication primarily used to protect healthy cells from the severe toxic effects of the chemotherapy drug methotrexate. Methotrexate is a primary choice in chemotherapy and may cause harmful side effects such as liver problems, kidney problems, lung problems, and blood disorders. Leucovorin Calcium is also used to enhance the effect of 5-fluorouracil (5-FU) in the treatment of metastatic colorectal cancer. Additionally, it may be used to treat certain types of folate-deficiency anemia.

Mechanism of Action:
Leucovorin Calcium (calcium folinate) is a folate analog. It is an active form of folic acid. It protects healthy cells from drugs that block folate. It also provides folate when the body cannot efficiently use regular folic acid. Calcium folinate also enhances the anticancer activity of 5-FU by increasing its binding to cancer cells.

Take Leucovorin Calcium exactly as your doctor prescribes, following the instructions in the Product Monograph in Canada accompanying the medication. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Leucovorin Calcium, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with Leucovorin Calcium (calcium folinate). It is not an exhaustive list, and individual reactions can vary. This information is for educational purposes and should not replace professional medical advice. Before starting Leucovorin Calcium, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are common side effects of Leucovorin Calcium; others are possible. Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms.
• Diarrhea;
• Mild rash;
• Nausea;
• Sleeping difficulties;
• Vomiting

Serious or rare side effects- Seek immediate medical attention or call emergency services if you experience any of the following:
• Severe allergic reaction, including rash, trouble breathing, or swelling of the face, lips, or tongue
• Severe diarrhea or dehydration;
• Signs of bone marrow suppression, such as unusual bleeding, easy bruising, or signs of infection

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Leucovorin Calcium, it is essential to discuss all your medical conditions, past and present, as well as all medications you are currently taking, with your doctor or pharmacist.

Leucovorin Calcium should not be used if:
• You have a known allergy to calcium folinate or any of the medication's ingredients.
• You have pernicious anemia or a vitamin B12 deficiency

Tell your doctor about all of your medical conditions, past and present, before starting Leucovorin Calcium. This is crucial because certain conditions can affect whether Leucovorin Calcium is right for you. These conditions may include, but are not limited to:
• Anemia of unknown cause
• Dehydration
• Kidney problems
• Liver problems
• Seizures

Drug Interactions:

Before taking Leucovorin Calcium, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the patient medication information.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Leucovorin Calcium. Leucovorin Calcium may interact with other medicines, but is not limited to:
• Anticonvulsants – Large doses of Leucovorin Calcium may counteract the anti-epileptic effect of certain seizure medications like phenobarbital, phenytoin, primidone, or valproic acid, increasing the frequency of seizures
• Ceftriaxone – combining Leucovorin Calcium with ceftriaxone can increase the risk of serious adverse effects
• Folate antagonists - Leucovorin Calcium may reduce the effectiveness of certain antibiotics and anti-parasitic drugs, such as trimethoprim and pyrimethamine, that work by blocking folate

Pregnancy and Breastfeeding:

Leucovorin Calcium is generally considered safe during pregnancy. Your doctor will consider the benefits and risks of this medicine before prescribing it in pregnancy. Calcium folinate is considered low-risk when breastfeeding. However, your doctor may monitor your baby. If you are pregnant, breastfeeding, or planning to become pregnant, it is crucial to consult your doctor immediately.

Frequently Asked Questions about Leucovorin Calcium at Canada Pharmacy Online:

Why is Leucovorin Calcium more affordable in Canada than in the United States?

Prescription drug prices, including Leucovorin Calcium, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. Visit our How to Order page for more information or to learn about the ordering process.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Leucovorin Calcium at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Leucovorin Calcium requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It typically takes 7-18 business days for your order to be delivered from our pharmacy.

Is there a generic for Leucovorin Calcium?

Yes, the generic calcium folinate is available.

Is leucovorin the same as folic acid?

No. It is an active form of folic acid that works even if the body cannot process regular folic acid.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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