Lialda (Mesalamine)

Name: Lialda
Brand: Shire
SKU: 6544
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Lialda

Manufacturer: Shire

Country: Canada

Dosage: 1200 mg

Qty-Price (USD):

Type:

Product: Lialda

Manufacturer: Shire

Country: United Kingdom

Dosage: 1200 mg

Qty-Price (USD):

Generic Equivalent of Lialda

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Mesalamine

Manufacturer: Generic

Country: India

Dosage: 1200 mg

Qty-Price (USD):

Lialda Information

medically reviewed by Carol Hou (BSc. Pharm) on April 28, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Lialda and Mesalamine at CanadaPharmacyOnline.com

Brand Lialda (mesalamine), manufactured by Shire (Mezavant), is available in many countries worldwide, including Canada and the United Kingdom.

Generic mesalamine is sourced from manufacturers that meet applicable regulatory standards for safety, efficacy, and quality. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Mesalamine:

Generic mesalamine contains the same active ingredient as brand-name Lialda and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Lialda. Studies have demonstrated bioequivalence between generic and brand-name mesalamine, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist, if you have any questions about using generic mesalamine.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand Lialda and generic mesalamine are commonly available in 1200 mg delayed-release tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Lialda (mesalamine) is a prescription medication used to reduce or eliminate the symptoms of ulcerative colitis. This medication is also used long-term to help prevent the symptoms of ulcerative colitis from recurring. (source: product labeling information)

Mechanism of Action:
Lialda (mesalamine) is an aminosalicylate medication formulated as delayed-release tablets. This delayed-release formulation is designed to allow the tablets to pass through the stomach intact, with the mesalamine being released primarily in the colon. Mesalamine acts locally within the colon to modulate inflammatory mediators, influencing pathways such as prostaglandin and leukotriene production, thereby reducing inflammation in the intestinal lining.

Take Lialda orally exactly as your doctor prescribes, following the instructions in the Full Prescribing Information | DailyMed. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Lialda, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below is not an exhaustive list of side effects; individual reactions can vary. It is crucial to discuss potential side effects and risks with your doctor or pharmacist before starting Lialda.

Common side effects - These are examples of some common side effects of Lialda, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Diarrhea (stay hydrated by drinking plenty of clear fluids)
• Flatulence (avoid gas-producing foods like beans, cabbage, and carbonated beverages. Eating smaller, more frequent meals may also help.)
• Headache (over-the-counter pain relievers such as acetaminophen may be used to treat headaches. If headaches become severe or frequent, contact your doctor)
• Nausea (take mesalamine with food to help reduce nausea. If nausea persists, speak to your doctor about anti-nausea medication)
• Stomach pain
• Upper respiratory infections

Less common but potentially severe side effects- Stop taking Lialda and seek immediate medical attention if you experience any of the following:
• Allergic reactions (including hives, itching, rash, swelling, and severe reactions like anaphylaxis)
• Heart problems (myocarditis - inflammation of the heart muscle)
• Kidney problems (mesalamine can cause kidney problems such as interstitial nephritis or kidney stones. Symptoms may include changes in urine output, flank pain, or blood in the urine. If you notice any of these symptoms, contact your doctor immediately.
• Liver problems (In rare cases, mesalamine can cause liver inflammation (hepatitis). Symptoms may include jaundice (yellowing of the skin or eyes), dark urine, abdominal pain, or unexplained fatigue. If you experience these symptoms, seek immediate medical attention.
• Mental health problems (Some patients have reported mood changes while taking mesalamine. If you notice any changes in mood or experience depression or anxiety, please contact your doctor.)
• Pancreatitis
• Severe skin reactions (Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS))

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Lialda.

Lialda should not be used if:
• Are allergic to mesalamine or other salicylates like aspirin or any of the inactive ingredients on this medication (Mesalamine is contraindicated in individuals with a known allergy to these substances. Allergic reactions can range from mild skin rashes to severe anaphylaxis. Inform your doctor of any known allergies before starting mesalamine.

Tell your doctor about all of your medical conditions, past and present, before starting Lialda. This is crucial because certain conditions can affect whether Lialda is right for you. These conditions may include, but are not limited to:
• You have severe kidney problems. (If you have a history of kidney disease, your doctor will carefully evaluate your kidney function before prescribing mesalamine. Regular monitoring of kidney function through blood tests is essential during treatment.
• You have severe liver problems (talk to your doctor if you have liver problems)
• You have a blockage in your stomach or intestines (such as pyloric stenosis)
• You have a history of severe skin reactions

Drug interactions:

Before taking Lialda, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Mesalamine Capsules: Package Insert / Prescribing Info.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Lialda may interact with other medicines, including but not limited to nephrotoxic agents such as NSAIDs, and immunosuppressants like azathioprine and 6-mercaptopurine.

Pregnancy and Breastfeeding:

You must consult with your doctor to discuss the potential risks and benefits before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Frequently Asked Questions about Lialda at Canada Pharmacy Online:

Why is Lialda more affordable in Canada than in the United States?

Prescription drug prices, including Lialda, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can the Lialda pill be split or crushed?

Swallow Lialda tablets whole; do not split or crush. Lialda tablets are formulated with a special delayed-release coating which is designed to protect the medication from being released in the stomach, ensuring that it reaches the lower intestines where it's needed to treat ulcerative colitis. Splitting, crushing, or chewing the tablets would damage this coating, causing the medication to be released prematurely.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products. How do I order from your pharmacy? Ordering Lialda from us is very simple. You can order online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Lialda at once, per your doctor's prescription.

Can I buy it over the counter from you?

No, Lialda requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for Lialda?

Yes, there is a generic alternative for this product called mesalamine.

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The generic alternative is not manufactured by the company that makes the brand product.

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This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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