Mezavant (Mesalamine)

Name: Mezavant
Brand: Shire
SKU: 7388
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Mezavant

Manufacturer: Shire

Country: Canada

Dosage: 1200 mg

Qty-Price (USD):

Generic Equivalent of Mezavant

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no generic product of Mezavant.

Mezavant Information

medically reviewed by Carol Hou (BSc. Pharm) on April 28, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Mezavant and Mesalamine at CanadaPharmacyOnline.com

Brand Mezavant (mesalamine), manufactured by Shire, is available in many countries worldwide, including Canada. Lialda is another brand name for mesalamine but may have different formulations and availability depending on the region. A generic version of Mezavant is not available at this time

Dosage:

Brand Mezavant is available in 1200 mg tablets. Your doctor will determine the appropriate dose based on your needs and medical conditions.

Usage:

Mezavant (mesalamine) is a prescription medication, specifically a 5-aminosalicylic acid (5-ASA), used to reduce inflammation in the colon and treat mild to moderate ulcerative colitis. It is used both for the treatment of active disease and for the maintenance of remission, helping to prevent symptom recurrence. (refer to the product monograph in Canada)

Mechanism of Action Mezavant contains mesalamine, 5-aminosalicylic acid (5-ASA), an aminosalicylate with anti-inflammatory properties. Mesalamine acts locally on the colonic mucosa to reduce inflammation. The precise mechanism of action of mesalamine is not fully elucidated, but it is known to modulate inflammatory mediators, including inhibition of cyclooxygenase and lipoxygenase pathways, and scavenging of free radicals. Mezavant tablets utilize Multi Matrix System (MMX) technology, which allows for controlled and extended release of mesalamine throughout the colon.

Take Mezavant orally exactly as your doctor prescribes, following the instructions in the Mesalamine: Package Insert / Prescribing Information. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Mezavant, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below is not an exhaustive list of side effects; individual reactions can vary. It is crucial to discuss potential side effects and risks with your doctor or pharmacist before starting Mezavant.

Common side effects - These are examples of some common side effects of Mezavant, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Abdominal pain
• Diarrhea (Stay hydrated by drinking plenty of clear fluids.)
• Flatulence (Avoid gas-producing foods like beans, cabbage, and carbonated beverages. Eating smaller, more frequent meals may also help.
• Headache (Take over-the-counter pain relievers such as acetaminophen to treat headaches; consult your doctor for severe or frequent headaches)
• Nausea (Taking mesalamine with food may reduce nausea; consult your doctor forpersistent nausea or if you need anti-nausea medication)

Less common but potentially severe side effects- Stop taking Mezavant and seek immediate medical attention if you experience any of the following:
• Allergic reactions (hives, itching, rash, swelling, anaphylaxis)
• Heart problems (myocarditis (inflammation of the heart muscle), pericarditis (inflammation of the lining of the heart)
• Kidney problems (interstitial nephritis, kidney stones). Symptoms may include changes in urine output, flank pain, and hematuria (blood in urine).

Contact your doctor immediately if these occur
• Liver problems (hepatitis; symptoms may include jaundice, dark urine, abdominal pain, unexplained fatigue). Seek immediate medical attention.
• Mental health problems (mood changes, including depression, anxiety); contact your doctor if you experience any changes in mood.
• Pancreatitis (it can be severe; it's vital to recognize the symptoms of pancreatitis and seek immediate medical attention if they occur)
• Pulmonary issues (Symptoms may include difficulty breathing and persistent cough)
• Severe skin reactions (Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS))

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Mezavant.

Mezavant should not be used if:
• You are allergic to mesalamine;
• You have a known allergy to salicylates (such as aspirin). Discuss this with your doctor, as it may influence the decision to use Mezavant.
• You are allergic to any of the inactive ingredients in this medication.

Mesalamine is contraindicated in individuals with a known allergy to these substances. Allergic reactions can range from mild skin rashes to severe anaphylaxis. Inform your doctor of any known allergies before starting mesalamine.

Tell your doctor about all of your medical conditions, past and present, before starting Mezavant. This is crucial because certain conditions can affect whether Mezavant is right for you. These conditions may include, but are not limited to:
• You have severe kidney problems. (If you have a history of kidney disease, your doctor will carefully evaluate your kidney function before prescribing mesalamine. Regular monitoring of kidney function through blood tests is essential during treatment.
• You have severe liver problems (talk to your doctor if you have liver problems)
• You have a severe intestinal obstruction.
• You have a history of severe skin reactions to mesalamine or salicylates.

Drug interactions:

Before taking Mezavant, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Mezavant product monograph in Canada.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Mezavant may interact with other medicines, including but not limited to nephrotoxic agents such as NSAIDs (all NSAIDs carry a risk of kidney problems, and that risk is increased when taken with mesalamine), and immunosuppressants like azathioprine and 6-mercaptopurine (increased risk of myelosuppression), and antacids (which may alter the release of mesalamine).

Pregnancy and Breastfeeding:

Mesalamine is generally considered relatively safe during pregnancy and breastfeeding. You must consult with your doctor to discuss the potential risks and benefits before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Frequently Asked Questions about Mezavant at Canada Pharmacy Online:

Why is Mezavant more affordable in Canada than in the United States?

Prescription drug prices, including Mezavant, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can the Mezavant pill be split or crushed?

Swallow the delayed-release tablets whole; do not split, chew, or crush them. Be careful not to break the protective coating on the delayed-release tablets.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purhcase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Mezavant at once, per your doctor's prescription.

Can I buy it over the counter from you?

No, Mezavant requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What happens when I miss a dose of Mezavant?

If you forget to take your Mezavant, take it right away when you remember. Then, resume your normal routine. However, if your next scheduled dose is coming up soon, just skip the missed one and carry on as usual. Never double up on doses. If you're unsure, ask your doctor or pharmacist.

How do I store Mezavant?

Mezavant should be stored in a cool, dry place at a temperature below 25°C, away from children and pets.

Blog Post

Did My Stomach Fall Asleep on the Job?
How Do the Most Popular Crohn’s Disease Drugs Stack Up?
Inflammatory Bowel Disease: Does Diet Play A Role?

Latest News

Anti-inflammatory drugs as potential antimicrobial agents: a review (published on April 7, 2025)

Similar Drugs in the category of Disorders of the Digestive Tract (IBS,Crohns Disease,Stomach):

Motilium Domperidone Asacol Creon Entocort EC

This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

Reviews From Real Customers